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View Protein Complex Details

Complex Overview

From Publication: Gavin A.C. et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature. 2006 Mar 30;440(7084):631-6. Epub 2006 Jan 22.
Notes: From the published set of protein complexes (core proteins only)
Complex Size: 10 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

U1 snRNP 7.309E-28 10 17 10 6292
small nuclear ribonucleoprotein complex 4.8032E-21 10 63 10 6292
U2-type spliceosomal complex 2.4212E-12 10 12 5 6292
commitment complex 2.4212E-12 10 12 5 6292
ribonucleoprotein complex 1.2207E-11 10 514 10 6292
spliceosomal complex 3.654E-9 10 45 5 6292
nuclear part 2.6498E-8 10 1103 10 6292
macromolecular complex 1.3754E-6 10 1635 10 6292
nucleus 1.2708E-5 10 2041 10 6292
organelle part 3.8887E-5 10 2282 10 6292
intracellular organelle part 3.8887E-5 10 2282 10 6292
membrane-bounded organelle 5.9511E-3 10 3771 10 6292
intracellular membrane-bounded organelle 5.9511E-3 10 3771 10 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

nuclear mRNA splicing, via spliceosome 5.8551E-19 10 99 10 6292
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 6.5056E-19 10 100 10 6292
RNA splicing, via transesterification reactions 1.3205E-18 10 107 10 6292
RNA splicing 1.1728E-17 10 132 10 6292
mRNA processing 6.5852E-17 10 156 10 6292
mRNA metabolic process 1.6065E-15 10 213 10 6292
RNA processing 5.7702E-13 10 380 10 6292
RNA metabolic process 6.1681E-9 10 954 10 6292
mRNA splice site selection 5.7692E-8 10 6 3 6292
gene expression 1.2084E-7 10 1283 10 6292
nucleic acid metabolic process 3.2281E-7 10 1415 10 6292
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 8.9255E-7 10 1566 10 6292
spliceosome assembly 2.3303E-6 10 18 3 6292
cellular nitrogen compound metabolic process 3.0471E-6 10 1770 10 6292
nitrogen compound metabolic process 3.4296E-6 10 1791 10 6292
cellular macromolecule metabolic process 3.9402E-5 10 2285 10 6292
macromolecule metabolic process 5.1966E-5 10 2349 10 6292
ribonucleoprotein complex assembly 3.3706E-4 10 92 3 6292
primary metabolic process 4.2311E-4 10 2896 10 6292
cellular metabolic process 6.7219E-4 10 3033 10 6292
metabolic process 1.0041E-3 10 3157 10 6292
nuclear mRNA 5'-splice site recognition 1.5893E-3 10 1 1 6292
cellular macromolecular complex assembly 2.4587E-3 10 182 3 6292
nuclear mRNA cis splicing, via spliceosome 4.7611E-3 10 3 1 6292
cellular macromolecular complex subunit organization 6.671E-3 10 259 3 6292
macromolecular complex assembly 8.3691E-3 10 281 3 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

RNA binding 4.0566E-13 10 367 10 6292
mRNA binding 3.9024E-12 10 35 6 6292
nucleic acid binding 1.6614E-10 10 666 10 6292
binding 1.3165E-7 10 1294 10 6292
pre-mRNA 5'-splice site binding 1.5893E-3 10 1 1 6292
U1 snRNA binding 1.5893E-3 10 1 1 6292
snRNA binding 7.9239E-3 10 5 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle