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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 5 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

Mre11 complex 2.4099E-10 5 3 3 6292
nuclear part 4.0435E-3 5 1103 4 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

double-strand break repair via break-induced replication 2.0214E-8 5 9 3 6292
meiotic DNA double-strand break formation 3.9687E-8 5 11 3 6292
meiosis I 1.1405E-7 5 79 4 6292
double-strand break repair via homologous recombination 3.6944E-7 5 22 3 6292
DNA recombination 5.0423E-7 5 114 4 6292
double-strand break repair via nonhomologous end joining 5.5136E-7 5 25 3 6292
recombinational repair 6.2313E-7 5 26 3 6292
non-recombinational repair 1.4314E-6 5 34 3 6292
meiotic DNA double-strand break processing 1.5153E-6 5 3 2 6292
M phase of meiotic cell cycle 1.9751E-6 5 160 4 6292
meiosis 1.9751E-6 5 160 4 6292
meiotic cell cycle 2.1811E-6 5 164 4 6292
nucleic acid phosphodiester bond hydrolysis 3.6208E-6 5 46 3 6292
DNA catabolic process, exonucleolytic 5.0479E-6 5 5 2 6292
DNA double-strand break processing 5.0479E-6 5 5 2 6292
double-strand break repair 6.9607E-6 5 57 3 6292
M phase 2.2511E-5 5 294 4 6292
DNA catabolic process 5.2834E-5 5 15 2 6292
cell cycle phase 5.9837E-5 5 376 4 6292
cell cycle process 1.7059E-4 5 490 4 6292
cell cycle 2.2393E-4 5 525 4 6292
DNA repair 2.6739E-4 5 192 3 6292
DNA metabolic process 3.428E-4 5 585 4 6292
response to DNA damage stimulus 4.927E-4 5 236 3 6292
anatomical structure homeostasis 8.6813E-4 5 286 3 6292
telomere organization 8.6813E-4 5 286 3 6292
telomere maintenance 8.6813E-4 5 286 3 6292
cellular response to stress 9.043E-4 5 290 3 6292
meiotic joint molecule formation 1.5888E-3 5 2 1 6292
cellular response to stimulus 1.9794E-3 5 379 3 6292
homeostatic process 2.453E-3 5 408 3 6292
response to stress 4.3416E-3 5 497 3 6292
regulation of biological quality 5.8393E-3 5 551 3 6292
chromosome organization 5.9616E-3 5 555 3 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

telomeric DNA binding 5.2903E-8 5 12 3 6292
adenylate kinase activity 3.0297E-6 5 4 2 6292
sequence-specific DNA binding 4.6705E-6 5 50 3 6292
nucleotide kinase activity 7.5694E-6 5 6 2 6292
DNA binding 1.2966E-5 5 256 4 6292
phosphotransferase activity, phosphate group as acceptor 2.771E-5 5 11 2 6292
nucleobase, nucleoside, nucleotide kinase activity 3.3242E-5 5 12 2 6292
double-stranded DNA binding 1.2698E-4 5 23 2 6292
structure-specific DNA binding 4.7163E-4 5 44 2 6292
nucleic acid binding 5.7016E-4 5 666 4 6292
binding 7.4489E-3 5 1294 4 6292
protein binding 7.8822E-3 5 612 3 6292

YRC Informatics Platform - Version 3.0
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