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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 13 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
BNI4
  • incipient cellular bud site
  • cellular bud neck
  • septin ring
  • barrier septum formation
  • chitin biosynthetic process
  • asymmetric protein localization
  • protein binding
  • BUD14
  • incipient cellular bud site
  • cellular bud tip
  • cellular bud neck
  • cytoskeleton organization
  • cell morphogenesis during vegetative growth
  • regulation of transcription, DNA-dependent
  • protein phosphatase type 1 regulator activity
  • GIP3
  • cytoplasm
  • mitochondrion
  • endoplasmic reticulum
  • ribosome
  • chromosome segregation
  • regulation of phosphoprotein phosphatase activity
  • protein phosphatase type 1 regulator activity
  • protein phosphatase 1 binding
  • GLC7
  • protein phosphatase type 1 complex
  • mRNA cleavage and polyadenylation specificity factor complex
  • cellular bud neck
  • spindle pole body
  • nuclear outer membrane
  • nucleolus
  • mating projection base
  • mitotic cell cycle spindle assembly checkpoint
  • cell morphogenesis during vegetative growth
  • protein amino acid dephosphorylation
  • chromosome segregation
  • cell budding
  • cellular ion homeostasis
  • meiosis
  • regulation of carbohydrate metabolic process
  • ascospore formation
  • response to heat
  • termination of RNA polymerase II transcription, poly(A)-coupled
  • glycogen metabolic process
  • termination of RNA polymerase II transcription, poly(A)-independent
  • histone dephosphorylation
  • protein serine/threonine phosphatase activity
  • phosphoprotein phosphatase activity
  • RNA binding
  • metal ion binding
  • hydrolase activity
  • GLC8
  • nucleus
  • cytoplasm
  • glycogen biosynthetic process
  • chromosome segregation
  • enzyme activator activity
  • HER1
  • cytoplasm
  • mitochondrion
  • ribosome
  • biological_process
  • molecular_function
  • PPZ1
  • nucleus
  • cytoplasm
  • extrinsic to plasma membrane
  • cellular sodium ion homeostasis
  • protein serine/threonine phosphatase activity
  • PUF3
  • cytoplasm
  • external side of mitochondrial outer membrane
  • mRNA catabolic process
  • aerobic respiration
  • mitochondrion localization
  • mitochondrion organization
  • nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
  • mRNA binding
  • SDS22
  • nucleus
  • cytoplasm
  • protein targeting
  • chromosome segregation
  • protein phosphatase type 1 regulator activity
  • enzyme regulator activity
  • SOL1
  • nucleus
  • cytoplasm
  • tRNA processing
  • tRNA export from nucleus
  • 6-phosphogluconolactonase activity
  • molecular_function
  • SOL2
  • cytoplasm
  • cytosol
  • tRNA processing
  • tRNA export from nucleus
  • telomere maintenance
  • 6-phosphogluconolactonase activity
  • molecular_function
  • YLR257W
  • cytoplasm
  • biological_process
  • molecular_function
  • YPI1
  • nucleus
  • glycogen metabolic process
  • protein amino acid dephosphorylation
  • phosphoprotein phosphatase inhibitor activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    external side of mitochondrial outer membrane 2.0661E-3 13 1 1 6292
    cellular bud neck 2.0717E-3 13 129 3 6292
    incipient cellular bud site 3.7109E-3 13 45 2 6292
    cellular bud 4.2448E-3 13 166 3 6292
    site of polarized growth 4.3905E-3 13 168 3 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    polysaccharide metabolic process 5.0112E-6 13 60 4 6292
    glycogen metabolic process 3.3022E-5 13 32 3 6292
    energy reserve metabolic process 3.3022E-5 13 32 3 6292
    dephosphorylation 6.5151E-5 13 40 3 6292
    cellular glucan metabolic process 8.1089E-5 13 43 3 6292
    glucan metabolic process 8.1089E-5 13 43 3 6292
    chromosome segregation 1.0135E-4 13 128 4 6292
    cell morphogenesis during vegetative growth 1.4073E-4 13 9 2 6292
    cellular polysaccharide metabolic process 1.6993E-4 13 55 3 6292
    energy derivation by oxidation of organic compounds 1.8285E-4 13 149 4 6292
    generation of precursor metabolites and energy 5.1341E-4 13 195 4 6292
    glucose metabolic process 1.2746E-3 13 109 3 6292
    tRNA export from nucleus 1.4452E-3 13 28 2 6292
    tRNA transport 1.4452E-3 13 28 2 6292
    protein amino acid dephosphorylation 1.4452E-3 13 28 2 6292
    hexose metabolic process 1.8493E-3 13 124 3 6292
    carbohydrate metabolic process 2.0214E-3 13 281 4 6292
    asymmetric protein localization 2.0661E-3 13 1 1 6292
    polysaccharide biosynthetic process 2.2564E-3 13 35 2 6292
    monosaccharide metabolic process 2.3599E-3 13 135 3 6292
    histone dephosphorylation 4.1283E-3 13 2 1 6292
    cellular sodium ion homeostasis 6.1865E-3 13 3 1 6292
    regulation of phosphoprotein phosphatase activity 6.1865E-3 13 3 1 6292
    regulation of dephosphorylation 6.1865E-3 13 3 1 6292
    sodium ion homeostasis 6.1865E-3 13 3 1 6292
    regulation of phosphatase activity 6.1865E-3 13 3 1 6292
    barrier septum formation 6.1865E-3 13 3 1 6292
    macromolecule localization 7.0697E-3 13 397 4 6292
    alcohol metabolic process 9.301E-3 13 220 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein phosphatase regulator activity 9.4952E-8 13 23 4 6292
    phosphatase regulator activity 9.4952E-8 13 23 4 6292
    protein phosphatase type 1 regulator activity 1.5001E-6 13 12 3 6292
    enzyme regulator activity 3.8104E-5 13 207 5 6292
    6-phosphogluconolactonase activity 3.9273E-5 13 5 2 6292
    carboxylesterase activity 8.894E-4 13 22 2 6292
    protein serine/threonine phosphatase activity 1.2455E-3 13 26 2 6292
    phosphoprotein phosphatase activity 3.3927E-3 13 43 2 6292
    hydrolase activity, acting on ester bonds 4.1009E-3 13 341 4 6292
    phosphatase binding 6.1865E-3 13 3 1 6292
    protein phosphatase binding 6.1865E-3 13 3 1 6292
    protein phosphatase 1 binding 6.1865E-3 13 3 1 6292
    phosphoprotein phosphatase inhibitor activity 6.1865E-3 13 3 1 6292
    phosphatase inhibitor activity 6.1865E-3 13 3 1 6292

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    Created and Maintained by: Michael Riffle