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View Protein Complex Details

Complex Overview

From Publication: Mewes, H. W. et al. MIPS: Analysis and annotation of proteins from whole genomes. Nucleic Acids Res. 32, D41-D44
Notes: MIPS hand-curated complex set. MIPS complex ID: 310
Complex Size: 13 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
GLE2
  • nuclear pore
  • mRNA export from nucleus
  • rRNA export from nucleus
  • nuclear envelope organization
  • nuclear pore organization
  • snRNP protein import into nucleus
  • mRNA-binding (hnRNP) protein import into nucleus
  • snRNA export from nucleus
  • protein import into nucleus
  • tRNA export from nucleus
  • NLS-bearing substrate import into nucleus
  • protein export from nucleus
  • ribosomal protein import into nucleus
  • structural molecule activity
  • NOP14
  • mitochondrion
  • Noc4p-Nop14p complex
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • snoRNA binding
  • NUP1
  • nuclear pore
  • protein export from nucleus
  • ribosomal protein import into nucleus
  • mRNA export from nucleus
  • rRNA export from nucleus
  • nuclear envelope organization
  • RNA export from nucleus
  • nuclear pore organization
  • snRNP protein import into nucleus
  • mRNA-binding (hnRNP) protein import into nucleus
  • snRNA export from nucleus
  • protein import into nucleus
  • tRNA export from nucleus
  • NLS-bearing substrate import into nucleus
  • protein binding
  • structural molecule activity
  • NUP100
  • nuclear pore
  • mRNA export from nucleus
  • rRNA export from nucleus
  • nuclear pore organization
  • snRNP protein import into nucleus
  • mRNA-binding (hnRNP) protein import into nucleus
  • snRNA export from nucleus
  • tRNA export from nucleus
  • NLS-bearing substrate import into nucleus
  • protein export from nucleus
  • ribosomal protein import into nucleus
  • structural molecule activity
  • NUP116
  • nuclear pore
  • mRNA export from nucleus
  • rRNA export from nucleus
  • nuclear pore organization
  • snRNP protein import into nucleus
  • mRNA-binding (hnRNP) protein import into nucleus
  • snRNA export from nucleus
  • protein import into nucleus
  • tRNA export from nucleus
  • NLS-bearing substrate import into nucleus
  • tRNA splicing, via endonucleolytic cleavage and ligation
  • protein export from nucleus
  • ribosomal protein import into nucleus
  • structural molecule activity
  • NUP133
  • nuclear pore
  • mRNA export from nucleus
  • rRNA export from nucleus
  • nuclear pore organization
  • snRNP protein import into nucleus
  • mRNA-binding (hnRNP) protein import into nucleus
  • snRNA export from nucleus
  • chromosome localization
  • tRNA export from nucleus
  • NLS-bearing substrate import into nucleus
  • DNA metabolic process
  • protein export from nucleus
  • ribosomal protein import into nucleus
  • structural molecule activity
  • NUP157
  • nuclear pore
  • mRNA export from nucleus
  • rRNA export from nucleus
  • nuclear pore organization
  • snRNP protein import into nucleus
  • mRNA-binding (hnRNP) protein import into nucleus
  • snRNA export from nucleus
  • tRNA export from nucleus
  • NLS-bearing substrate import into nucleus
  • protein export from nucleus
  • ribosomal protein import into nucleus
  • structural molecule activity
  • NUP159
  • nuclear pore
  • mRNA export from nucleus
  • rRNA export from nucleus
  • ribosomal subunit export from nucleus
  • nuclear pore organization
  • structural molecule activity
  • NUP170
  • nuclear pore
  • mRNA export from nucleus
  • rRNA export from nucleus
  • nuclear pore organization
  • snRNP protein import into nucleus
  • mRNA-binding (hnRNP) protein import into nucleus
  • snRNA export from nucleus
  • tRNA export from nucleus
  • NLS-bearing substrate import into nucleus
  • chromosome segregation
  • protein export from nucleus
  • protein import into nucleus, docking
  • ribosomal protein import into nucleus
  • structural molecule activity
  • NUP188
  • nuclear pore
  • mRNA export from nucleus
  • rRNA export from nucleus
  • nuclear pore organization
  • snRNP protein import into nucleus
  • mRNA-binding (hnRNP) protein import into nucleus
  • snRNA export from nucleus
  • tRNA export from nucleus
  • NLS-bearing substrate import into nucleus
  • protein export from nucleus
  • ribosomal protein import into nucleus
  • structural molecule activity
  • NUP2
  • nuclear chromatin
  • mitochondrion
  • nuclear pore
  • mRNA export from nucleus
  • rRNA export from nucleus
  • nuclear pore organization
  • snRNP protein import into nucleus
  • mRNA-binding (hnRNP) protein import into nucleus
  • snRNA export from nucleus
  • tRNA export from nucleus
  • NLS-bearing substrate import into nucleus
  • chromatin silencing
  • protein export from nucleus
  • chromatin silencing at telomere
  • ribosomal protein import into nucleus
  • structural molecule activity
  • NUP42
  • nuclear pore
  • mRNA export from nucleus
  • rRNA export from nucleus
  • nuclear pore organization
  • snRNP protein import into nucleus
  • mRNA-binding (hnRNP) protein import into nucleus
  • snRNA export from nucleus
  • tRNA export from nucleus
  • NLS-bearing substrate import into nucleus
  • protein export from nucleus
  • ribosomal protein import into nucleus
  • structural molecule activity
  • POM152
  • mitochondrion
  • nuclear pore
  • mRNA export from nucleus
  • rRNA export from nucleus
  • nuclear pore organization
  • snRNP protein import into nucleus
  • mRNA-binding (hnRNP) protein import into nucleus
  • snRNA export from nucleus
  • tRNA export from nucleus
  • NLS-bearing substrate import into nucleus
  • protein export from nucleus
  • ribosomal protein import into nucleus
  • structural molecule activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    pore complex 3.3534E-25 13 52 12 6292
    nuclear pore 3.3534E-25 13 52 12 6292
    nuclear envelope 2.1494E-20 13 199 13 6292
    integral to membrane 1.9124E-16 13 255 12 6292
    endomembrane system 2.1557E-16 13 398 13 6292
    intrinsic to membrane 2.6629E-16 13 262 12 6292
    envelope 4.9692E-15 13 505 13 6292
    organelle envelope 4.9692E-15 13 505 13 6292
    membrane part 1.741E-13 13 662 13 6292
    nuclear part 1.3925E-10 13 1103 13 6292
    protein complex 2.0707E-10 13 1137 13 6292
    membrane 4.0992E-10 13 1198 13 6292
    macromolecular complex 2.3774E-8 13 1635 13 6292
    nucleus 4.29E-7 13 2041 13 6292
    intracellular organelle part 1.8381E-6 13 2282 13 6292
    organelle part 1.8381E-6 13 2282 13 6292
    membrane-bounded organelle 1.2767E-3 13 3771 13 6292
    intracellular membrane-bounded organelle 1.2767E-3 13 3771 13 6292
    intracellular organelle 3.4477E-3 13 4070 13 6292
    organelle 3.4587E-3 13 4071 13 6292
    Noc4p-Nop14p complex 4.1283E-3 13 2 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    rRNA transport 2.8351E-29 13 27 12 6292
    rRNA export from nucleus 2.8351E-29 13 27 12 6292
    nuclear pore organization 4.9606E-29 13 28 12 6292
    ribosomal protein import into nucleus 6.916E-27 13 23 11 6292
    snRNP protein import into nucleus 6.916E-27 13 23 11 6292
    NLS-bearing substrate import into nucleus 6.916E-27 13 23 11 6292
    snRNA transport 6.916E-27 13 23 11 6292
    snRNA export from nucleus 6.916E-27 13 23 11 6292
    mRNA-binding (hnRNP) protein import into nucleus 2.2787E-26 13 25 11 6292
    tRNA transport 1.0968E-25 13 28 11 6292
    tRNA export from nucleus 1.0968E-25 13 28 11 6292
    protein export from nucleus 6.5823E-25 13 32 11 6292
    nucleus organization 9.0675E-25 13 56 12 6292
    mRNA transport 1.1804E-23 13 68 12 6292
    mRNA export from nucleus 1.1804E-23 13 68 12 6292
    RNA export from nucleus 9.7486E-23 13 80 12 6292
    RNA transport 1.1442E-22 13 81 12 6292
    nucleic acid transport 1.1442E-22 13 81 12 6292
    establishment of RNA localization 1.1442E-22 13 81 12 6292
    protein localization in nucleus 1.1473E-22 13 48 11 6292
    protein import into nucleus 1.1473E-22 13 48 11 6292
    nuclear import 1.1473E-22 13 48 11 6292
    RNA localization 5.8605E-22 13 92 12 6292
    nucleobase, nucleoside, nucleotide and nucleic acid transport 1.0084E-21 13 96 12 6292
    nuclear export 2.4659E-21 13 103 12 6292
    nuclear transport 4.6288E-20 13 130 12 6292
    nucleocytoplasmic transport 4.6288E-20 13 130 12 6292
    protein import 1.721E-18 13 108 11 6292
    ribosome biogenesis 3.3886E-17 13 346 13 6292
    protein localization in organelle 6.798E-17 13 149 11 6292
    ribonucleoprotein complex biogenesis 9.4812E-17 13 374 13 6292
    cellular macromolecular complex subunit organization 2.3133E-16 13 259 12 6292
    protein targeting 1.1453E-14 13 235 11 6292
    macromolecular complex subunit organization 1.1516E-14 13 357 12 6292
    intracellular protein transport 2.8489E-14 13 255 11 6292
    macromolecule localization 4.1717E-14 13 397 12 6292
    protein transport 5.1663E-14 13 269 11 6292
    establishment of protein localization 5.6102E-14 13 271 11 6292
    cellular protein localization 6.3412E-14 13 274 11 6292
    cellular macromolecule localization 9.4459E-14 13 284 11 6292
    protein localization 1.9387E-13 13 303 11 6292
    cellular component biogenesis 3.2337E-13 13 694 13 6292
    intracellular transport 2.278E-12 13 553 12 6292
    establishment of localization in cell 5.954E-12 13 599 12 6292
    cellular localization 1.3946E-11 13 643 12 6292
    transport 2.6339E-9 13 997 12 6292
    establishment of localization 3.0011E-9 13 1008 12 6292
    localization 5.4565E-9 13 1060 12 6292
    organelle organization 1.1295E-8 13 1127 12 6292
    cellular component organization 6.186E-7 13 1582 12 6292
    nuclear envelope organization 8.2282E-5 13 7 2 6292
    protein import into nucleus, docking 8.2408E-3 13 4 1 6292
    chromosome localization 8.2408E-3 13 4 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural molecule activity 6.1449E-15 13 339 12 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle