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View Protein Complex Details

Complex Overview

From Publication: Mewes, H. W. et al. MIPS: Analysis and annotation of proteins from whole genomes. Nucleic Acids Res. 32, D41-D44
Notes: MIPS hand-curated complex set. MIPS complex ID: 133.40
Complex Size: 4 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
SRB8
  • transcription factor complex
    		•
  • negative regulation of transcription from RNA polymerase II promoter
  • telomere maintenance
    		•
  • RNA polymerase II transcription mediator activity
    		•
    SSN2
  • transcription factor complex
    		•
  • negative regulation of transcription from RNA polymerase II promoter
  • telomere maintenance
    		•
  • general RNA polymerase II transcription factor activity
    		•
    SSN3
  • transcription factor complex
    		•
  • negative regulation of transcription from RNA polymerase II promoter
  • telomere maintenance
  • protein amino acid phosphorylation
  • regulation of transcription
  • meiosis
    		•
  • general RNA polymerase II transcription factor activity
  • cyclin-dependent protein kinase activity
    		•
    SSN8
  • transcription factor complex
    		•
  • negative regulation of transcription from RNA polymerase II promoter
  • telomere maintenance
  • meiosis
    		•
  • cyclin-dependent protein kinase regulator activity
  • general RNA polymerase II transcription factor activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    transcription factor complex 1.4893E-8 4 71 4 6292
    nucleoplasm part 2.2451E-6 4 245 4 6292
    nucleoplasm 3.0322E-6 4 264 4 6292
    nuclear lumen 2.6539E-5 4 453 4 6292
    organelle lumen 1.2008E-4 4 660 4 6292
    intracellular organelle lumen 1.2008E-4 4 660 4 6292
    membrane-enclosed lumen 1.5203E-4 4 700 4 6292
    nuclear part 9.4015E-4 4 1103 4 6292
    protein complex 1.0617E-3 4 1137 4 6292
    macromolecular complex 4.5471E-3 4 1635 4 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    negative regulation of transcription from RNA polymerase II promoter 7.4742E-9 4 60 4 6292
    negative regulation of transcription, DNA-dependent 3.7337E-7 4 157 4 6292
    negative regulation of RNA metabolic process 3.8306E-7 4 158 4 6292
    negative regulation of gene expression 4.4528E-7 4 164 4 6292
    negative regulation of transcription 4.4528E-7 4 164 4 6292
    negative regulation of macromolecule biosynthetic process 5.7866E-7 4 175 4 6292
    negative regulation of nitrogen compound metabolic process 6.483E-7 4 180 4 6292
    negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 6.483E-7 4 180 4 6292
    negative regulation of biosynthetic process 7.8928E-7 4 189 4 6292
    negative regulation of cellular biosynthetic process 7.8928E-7 4 189 4 6292
    negative regulation of macromolecule metabolic process 8.4103E-7 4 192 4 6292
    negative regulation of cellular metabolic process 1.1839E-6 4 209 4 6292
    negative regulation of metabolic process 1.2069E-6 4 210 4 6292
    regulation of transcription from RNA polymerase II promoter 1.6808E-6 4 228 4 6292
    negative regulation of cellular process 2.4353E-6 4 250 4 6292
    negative regulation of biological process 2.555E-6 4 253 4 6292
    anatomical structure homeostasis 4.1838E-6 4 286 4 6292
    telomere organization 4.1838E-6 4 286 4 6292
    telomere maintenance 4.1838E-6 4 286 4 6292
    transcription from RNA polymerase II promoter 7.9001E-6 4 335 4 6292
    regulation of transcription, DNA-dependent 1.0315E-5 4 358 4 6292
    regulation of RNA metabolic process 1.0906E-5 4 363 4 6292
    regulation of transcription 1.367E-5 4 384 4 6292
    homeostatic process 1.7438E-5 4 408 4 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.867E-5 4 415 4 6292
    regulation of nitrogen compound metabolic process 1.8852E-5 4 416 4 6292
    regulation of gene expression 2.4707E-5 4 445 4 6292
    regulation of macromolecule biosynthetic process 2.7251E-5 4 456 4 6292
    regulation of cellular biosynthetic process 3.1296E-5 4 472 4 6292
    regulation of biosynthetic process 3.1563E-5 4 473 4 6292
    regulation of macromolecule metabolic process 3.5776E-5 4 488 4 6292
    transcription, DNA-dependent 4.0396E-5 4 503 4 6292
    RNA biosynthetic process 4.2031E-5 4 508 4 6292
    regulation of primary metabolic process 4.4059E-5 4 514 4 6292
    regulation of cellular metabolic process 5.2125E-5 4 536 4 6292
    regulation of metabolic process 5.655E-5 4 547 4 6292
    regulation of biological quality 5.8227E-5 4 551 4 6292
    transcription 5.8652E-5 4 552 4 6292
    chromosome organization 5.9941E-5 4 555 4 6292
    DNA metabolic process 7.4032E-5 4 585 4 6292
    regulation of cellular process 2.5447E-4 4 796 4 6292
    regulation of biological process 2.9228E-4 4 824 4 6292
    RNA metabolic process 5.2568E-4 4 954 4 6292
    organelle organization 1.0248E-3 4 1127 4 6292
    cellular macromolecule biosynthetic process 1.2614E-3 4 1187 4 6292
    macromolecule biosynthetic process 1.27E-3 4 1189 4 6292
    biological regulation 1.3758E-3 4 1213 4 6292
    gene expression 1.7224E-3 4 1283 4 6292
    nucleic acid metabolic process 2.5494E-3 4 1415 4 6292
    M phase of meiotic cell cycle 3.7283E-3 4 160 2 6292
    meiosis 3.7283E-3 4 160 2 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.8261E-3 4 1566 4 6292
    cellular biosynthetic process 3.8359E-3 4 1567 4 6292
    meiotic cell cycle 3.9142E-3 4 164 2 6292
    cellular component organization 3.9851E-3 4 1582 4 6292
    biosynthetic process 4.1907E-3 4 1602 4 6292
    cellular nitrogen compound metabolic process 6.2471E-3 4 1770 4 6292
    nitrogen compound metabolic process 6.5492E-3 4 1791 4 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    general RNA polymerase II transcription factor activity 9.7387E-9 4 64 4 6292
    RNA polymerase II transcription factor activity 1.741E-7 4 130 4 6292
    transcription regulator activity 8.286E-6 4 339 4 6292
    cyclin-dependent protein kinase activity 5.0773E-3 4 8 1 6292
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