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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 4 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
SPT15
  • nucleus
  • RNA polymerase I transcription factor complex
  • transcription factor TFIID complex
  • transcription factor TFIIIB complex
  • transcription from RNA polymerase III promoter
  • transcription initiation from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
  • transcription initiation from RNA polymerase II promoter
  • DNA binding
  • RNA polymerase I transcription factor activity
  • protein homodimerization activity
  • general RNA polymerase II transcription factor activity
  • DNA bending activity
  • RNA polymerase III transcription factor activity
  • TAF1
  • transcription factor TFIID complex
  • protein amino acid phosphorylation
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • histone acetyltransferase activity
  • general RNA polymerase II transcription factor activity
  • protein serine/threonine kinase activity
  • TAF5
  • transcription factor TFIID complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • protein amino acid acetylation
  • histone acetylation
  • chromatin organization
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • VPS1
  • membrane fraction
  • peroxisome
  • cytoplasm
  • mitochondrial outer membrane
  • protein retention in Golgi apparatus
  • peroxisome organization
  • vacuolar transport
  • protein targeting to vacuole
  • actin cytoskeleton organization
  • GTPase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    transcription factor TFIID complex 4.3797E-8 4 15 3 6292
    DNA-directed RNA polymerase II, holoenzyme 2.6552E-6 4 56 3 6292
    transcription factor complex 5.4647E-6 4 71 3 6292
    nucleoplasm part 2.2664E-4 4 245 3 6292
    nucleoplasm 2.8316E-4 4 264 3 6292
    nuclear lumen 1.404E-3 4 453 3 6292
    transcription factor TFIIIB complex 1.9063E-3 4 3 1 6292
    organelle lumen 4.2376E-3 4 660 3 6292
    intracellular organelle lumen 4.2376E-3 4 660 3 6292
    membrane-enclosed lumen 5.0309E-3 4 700 3 6292
    RNA polymerase I transcription factor complex 5.7106E-3 4 9 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    transcription initiation from RNA polymerase II promoter 1.5548E-6 4 47 3 6292
    transcription initiation 2.9548E-6 4 58 3 6292
    regulation of transcription involved in G1 phase of mitotic cell cycle 2.7517E-5 4 14 2 6292
    protein complex biogenesis 5.761E-5 4 155 3 6292
    protein complex assembly 5.761E-5 4 155 3 6292
    G1 phase 1.0585E-4 4 27 2 6292
    G1 phase of mitotic cell cycle 1.0585E-4 4 27 2 6292
    macromolecular complex assembly 3.4098E-4 4 281 3 6292
    transcription from RNA polymerase II promoter 5.749E-4 4 335 3 6292
    macromolecular complex subunit organization 6.9425E-4 4 357 3 6292
    cellular component assembly 8.6824E-4 4 385 3 6292
    interphase of mitotic cell cycle 1.3833E-3 4 97 2 6292
    interphase 1.3833E-3 4 97 2 6292
    transcription, DNA-dependent 1.9112E-3 4 503 3 6292
    RNA biosynthetic process 1.9676E-3 4 508 3 6292
    transcription 2.5116E-3 4 552 3 6292
    cellular component organization 3.9851E-3 4 1582 4 6292
    cellular component biogenesis 4.9063E-3 4 694 3 6292
    transcription initiation from RNA polymerase III promoter 6.9763E-3 4 11 1 6292
    regulation of transcription from RNA polymerase II promoter 7.4744E-3 4 228 2 6292
    protein localization in Golgi apparatus 8.2408E-3 4 13 1 6292
    protein retention in Golgi apparatus 8.2408E-3 4 13 1 6292
    mitotic cell cycle 9.2992E-3 4 255 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    general RNA polymerase II transcription factor activity 3.987E-6 4 64 3 6292
    RNA polymerase II transcription factor activity 3.3964E-5 4 130 3 6292
    transcription regulator activity 5.9551E-4 4 339 3 6292
    protein homodimerization activity 1.2712E-3 4 2 1 6292
    identical protein binding 1.9063E-3 4 3 1 6292
    protein dimerization activity 3.8098E-3 4 6 1 6292
    RNA polymerase I transcription factor activity 6.3436E-3 4 10 1 6292
    RNA polymerase III transcription factor activity 6.3436E-3 4 10 1 6292
    DNA bending activity 8.2408E-3 4 13 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle