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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 17 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
DIP2
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • EMG1
  • nucleus
  • cytoplasm
  • nuclear microtubule
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • IMP3
  • small-subunit processome
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • MPP10
  • nucleus
  • small-subunit processome
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • NAN1
  • RENT complex
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • NOC4
  • nucleus
  • Noc4p-Nop14p complex
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • NOP1
  • nuclear outer membrane
  • nucleolus
  • ribosome
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • RNA methylation
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • snoRNA 3'-end processing
  • methyltransferase activity
  • PNO1
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • protein complex assembly
  • ribosome biogenesis
  • rRNA processing
  • unfolded protein binding
  • PWP2
  • cytoplasm
  • nuclear outer membrane
  • 90S preribosome
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • cytokinesis
  • ribosome biogenesis
  • snoRNA binding
  • UTP10
  • mitochondrion
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP20
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • rRNA processing
  • snoRNA binding
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • UTP30
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • UTP4
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP6
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP7
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • UTP8
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    small nucleolar ribonucleoprotein complex 2.1418E-28 17 72 15 6292
    nuclear outer membrane 1.8651E-17 17 86 11 6292
    nuclear membrane 7.5098E-17 17 97 11 6292
    ribonucleoprotein complex 4.6406E-15 17 514 15 6292
    outer membrane 7.2966E-14 17 178 11 6292
    organelle outer membrane 7.2966E-14 17 178 11 6292
    nuclear envelope 2.5258E-13 17 199 11 6292
    nuclear membrane-endoplasmic reticulum network 1.3807E-12 17 232 11 6292
    endomembrane system 4.9714E-10 17 398 11 6292
    nucleolus 8.7226E-10 17 211 9 6292
    envelope 6.3606E-9 17 505 11 6292
    organelle envelope 6.3606E-9 17 505 11 6292
    membrane part 1.1044E-7 17 662 11 6292
    macromolecular complex 1.2396E-7 17 1635 15 6292
    organelle membrane 1.7533E-7 17 692 11 6292
    nuclear lumen 6.9419E-7 17 453 9 6292
    preribosome 1.6097E-6 17 34 4 6292
    nuclear part 2.0738E-6 17 1103 12 6292
    organelle lumen 1.6305E-5 17 660 9 6292
    intracellular organelle lumen 1.6305E-5 17 660 9 6292
    membrane-enclosed lumen 2.6414E-5 17 700 9 6292
    membrane 4.5594E-5 17 1198 11 6292
    small-subunit processome 1.0242E-4 17 6 2 6292
    non-membrane-bounded organelle 3.2651E-4 17 959 9 6292
    intracellular non-membrane-bounded organelle 3.2651E-4 17 959 9 6292
    90S preribosome 9.1252E-4 17 17 2 6292
    nucleus 1.4135E-3 17 2041 12 6292
    intracellular organelle part 4.1965E-3 17 2282 12 6292
    organelle part 4.1965E-3 17 2282 12 6292
    Noc4p-Nop14p complex 5.3968E-3 17 2 1 6292
    nucleolar part 6.3538E-3 17 45 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribosome biogenesis 2.6351E-22 17 346 17 6292
    rRNA processing 6.5193E-22 17 128 14 6292
    maturation of SSU-rRNA 8.4129E-22 17 59 12 6292
    ribonucleoprotein complex biogenesis 1.0198E-21 17 374 17 6292
    rRNA metabolic process 1.7675E-21 17 137 14 6292
    ncRNA processing 1.2094E-18 17 215 14 6292
    ncRNA metabolic process 1.55E-17 17 257 14 6292
    cellular component biogenesis 4.4392E-17 17 694 17 6292
    RNA processing 3.9317E-15 17 380 14 6292
    RNA metabolic process 1.3546E-9 17 954 14 6292
    gene expression 7.3773E-8 17 1283 14 6292
    nucleic acid metabolic process 2.7189E-7 17 1415 14 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.0381E-6 17 1566 14 6292
    cellular nitrogen compound metabolic process 5.1462E-6 17 1770 14 6292
    nitrogen compound metabolic process 5.9975E-6 17 1791 14 6292
    cellular macromolecule metabolic process 1.3415E-4 17 2285 14 6292
    macromolecule metabolic process 1.8936E-4 17 2349 14 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 5.2669E-4 17 13 2 6292
    rRNA modification 1.0249E-3 17 18 2 6292
    ribosomal small subunit biogenesis 2.1497E-3 17 26 2 6292
    primary metabolic process 2.4078E-3 17 2896 14 6292
    cellular process 2.5051E-3 17 4426 17 6292
    cellular metabolic process 4.1361E-3 17 3033 14 6292
    metabolic process 6.562E-3 17 3157 14 6292
    ncRNA 5'-end processing 8.0849E-3 17 3 1 6292
    endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.0849E-3 17 3 1 6292
    endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.0849E-3 17 3 1 6292
    rRNA 5'-end processing 8.0849E-3 17 3 1 6292
    RNA 5'-end processing 8.0849E-3 17 3 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    snoRNA binding 6.7761E-23 17 31 11 6292
    RNA binding 2.0719E-10 17 367 11 6292
    nucleic acid binding 1.1762E-7 17 666 11 6292
    binding 1.201E-5 17 1294 12 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle