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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 12 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
EMG1
  • nucleus
  • cytoplasm
  • nuclear microtubule
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • ENP1
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • preribosome, small subunit precursor
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • IMP3
  • small-subunit processome
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • MPP10
  • nucleus
  • small-subunit processome
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • NOP1
  • nuclear outer membrane
  • nucleolus
  • ribosome
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • RNA methylation
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • snoRNA 3'-end processing
  • methyltransferase activity
  • PNO1
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • protein complex assembly
  • ribosome biogenesis
  • rRNA processing
  • unfolded protein binding
  • RPS13
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • UTP10
  • mitochondrion
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP20
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • rRNA processing
  • snoRNA binding
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • UTP4
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP6
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    small nucleolar ribonucleoprotein complex 4.3029E-16 12 72 9 6292
    nuclear outer membrane 4.1423E-13 12 86 8 6292
    nuclear membrane 1.1212E-12 12 97 8 6292
    ribonucleoprotein complex 1.0889E-11 12 514 11 6292
    outer membrane 1.5777E-10 12 178 8 6292
    organelle outer membrane 1.5777E-10 12 178 8 6292
    nuclear envelope 3.869E-10 12 199 8 6292
    nuclear membrane-endoplasmic reticulum network 1.322E-9 12 232 8 6292
    nucleolus 2.9678E-8 12 211 7 6292
    endomembrane system 9.4636E-8 12 398 8 6292
    preribosome 3.4126E-7 12 34 4 6292
    envelope 6.0518E-7 12 505 8 6292
    organelle envelope 6.0518E-7 12 505 8 6292
    macromolecular complex 3.2574E-6 12 1635 11 6292
    membrane part 4.8565E-6 12 662 8 6292
    nuclear lumen 5.523E-6 12 453 7 6292
    organelle membrane 6.8078E-6 12 692 8 6292
    small-subunit processome 4.981E-5 12 6 2 6292
    organelle lumen 6.6876E-5 12 660 7 6292
    intracellular organelle lumen 6.6876E-5 12 660 7 6292
    non-membrane-bounded organelle 7.9037E-5 12 959 8 6292
    intracellular non-membrane-bounded organelle 7.9037E-5 12 959 8 6292
    membrane-enclosed lumen 9.8106E-5 12 700 7 6292
    nuclear part 2.2105E-4 12 1103 8 6292
    membrane 4.0254E-4 12 1198 8 6292
    intracellular organelle part 7.3047E-3 12 2282 9 6292
    organelle part 7.3047E-3 12 2282 9 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    rRNA processing 5.4362E-16 12 128 10 6292
    rRNA metabolic process 1.0959E-15 12 137 10 6292
    maturation of SSU-rRNA 1.758E-14 12 59 8 6292
    ncRNA processing 1.0983E-13 12 215 10 6292
    ribosome biogenesis 1.3634E-13 12 346 11 6292
    ribonucleoprotein complex biogenesis 3.2343E-13 12 374 11 6292
    ncRNA metabolic process 6.6909E-13 12 257 10 6292
    RNA processing 3.4115E-11 12 380 10 6292
    cellular component biogenesis 2.9584E-10 12 694 11 6292
    gene expression 2.393E-7 12 1283 11 6292
    RNA metabolic process 3.0352E-7 12 954 10 6292
    nucleic acid metabolic process 1.3529E-5 12 1415 10 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.5389E-5 12 1566 10 6292
    cellular nitrogen compound metabolic process 1.1182E-4 12 1770 10 6292
    cellular macromolecule metabolic process 1.144E-4 12 2285 11 6292
    nitrogen compound metabolic process 1.2483E-4 12 1791 10 6292
    macromolecule metabolic process 1.5296E-4 12 2349 11 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.571E-4 12 13 2 6292
    rRNA modification 5.0164E-4 12 18 2 6292
    primary metabolic process 1.3504E-3 12 2896 11 6292
    cellular metabolic process 2.1697E-3 12 3033 11 6292
    metabolic process 3.2647E-3 12 3157 11 6292
    ncRNA 5'-end processing 5.7116E-3 12 3 1 6292
    endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 5.7116E-3 12 3 1 6292
    endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 5.7116E-3 12 3 1 6292
    rRNA 5'-end processing 5.7116E-3 12 3 1 6292
    RNA 5'-end processing 5.7116E-3 12 3 1 6292
    RNA modification 7.4934E-3 12 70 2 6292
    maturation of 5.8S rRNA 7.6087E-3 12 4 1 6292
    cleavage involved in rRNA processing 7.6087E-3 12 4 1 6292
    maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 7.6087E-3 12 4 1 6292
    endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 7.6087E-3 12 4 1 6292
    endonucleolytic cleavage involved in rRNA processing 7.6087E-3 12 4 1 6292
    endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 7.6087E-3 12 4 1 6292
    snoRNA 3'-end processing 9.5026E-3 12 5 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    snoRNA binding 2.6528E-14 12 31 7 6292
    RNA binding 1.333E-6 12 367 7 6292
    nucleic acid binding 7.0946E-5 12 666 7 6292
    binding 6.9994E-4 12 1294 8 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle