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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 9 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
FUN12
  • mitochondrion
  • translational initiation
  • translation initiation factor activity
  • GTPase activity
  • KEM1
  • cytoplasm
  • cytoplasmic mRNA processing body
  • nuclear outer membrane
  • filamentous growth
  • response to exogenous dsRNA
  • telomere maintenance
  • traversing start control point of mitotic cell cycle
  • karyogamy involved in conjugation with cellular fusion
  • mRNA catabolic process
  • 5'-3' exoribonuclease activity
  • deoxyribonuclease activity
  • recombinase activity
  • PRP43
  • mitochondrion
  • spliceosomal complex
  • nuclear outer membrane
  • maturation of SSU-rRNA
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • rRNA processing
  • processing of 27S pre-rRNA
  • ATP-dependent RNA helicase activity
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS4B, RPS4A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • STM1
  • cytoplasm
  • nuclear telomere cap complex
  • anti-apoptosis
  • telomere maintenance
  • DNA binding
  • telomeric DNA binding
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • YGR054W
  • ribosome
  • translational initiation
  • translation initiation factor activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribonucleoprotein complex 7.2713E-7 9 514 7 6292
    macromolecular complex 1.4222E-4 9 1635 8 6292
    nuclear outer membrane 1.9518E-4 9 86 3 6292
    90S preribosome 2.4464E-4 9 17 2 6292
    nuclear membrane 2.7897E-4 9 97 3 6292
    cytosolic ribosome 3.1441E-4 9 101 3 6292
    ribosome 4.634E-4 9 290 4 6292
    cytosolic part 5.4863E-4 9 122 3 6292
    non-membrane-bounded organelle 6.8534E-4 9 959 6 6292
    intracellular non-membrane-bounded organelle 6.8534E-4 9 959 6 6292
    preribosome 9.9648E-4 9 34 2 6292
    cytosolic small ribosomal subunit 1.245E-3 9 38 2 6292
    outer membrane 1.6491E-3 9 178 3 6292
    organelle outer membrane 1.6491E-3 9 178 3 6292
    ribosomal subunit 1.7864E-3 9 183 3 6292
    nuclear envelope 2.2736E-3 9 199 3 6292
    nuclear membrane-endoplasmic reticulum network 3.5247E-3 9 232 3 6292
    small ribosomal subunit 4.5346E-3 9 73 2 6292
    cytosol 6.2396E-3 9 284 3 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    maturation of SSU-rRNA 6.3216E-5 9 59 3 6292
    translation 7.6567E-5 9 376 5 6292
    cellular macromolecule metabolic process 1.0877E-4 9 2285 9 6292
    macromolecule metabolic process 1.3953E-4 9 2349 9 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.4073E-4 9 13 2 6292
    gene expression 3.5247E-4 9 1283 7 6292
    rRNA processing 6.3162E-4 9 128 3 6292
    rRNA metabolic process 7.7062E-4 9 137 3 6292
    primary metabolic process 9.2081E-4 9 2896 9 6292
    cellular metabolic process 1.3966E-3 9 3033 9 6292
    negative regulation of programmed cell death 1.4304E-3 9 1 1 6292
    negative regulation of cell death 1.4304E-3 9 1 1 6292
    anti-apoptosis 1.4304E-3 9 1 1 6292
    negative regulation of apoptosis 1.4304E-3 9 1 1 6292
    translational initiation 1.5203E-3 9 42 2 6292
    metabolic process 2.004E-3 9 3157 9 6292
    regulation of translation 2.7869E-3 9 57 2 6292
    ncRNA processing 2.8373E-3 9 215 3 6292
    posttranscriptional regulation of gene expression 3.186E-3 9 61 2 6292
    regulation of cellular protein metabolic process 3.9454E-3 9 68 2 6292
    regulation of protein metabolic process 4.6571E-3 9 74 2 6292
    ncRNA metabolic process 4.7107E-3 9 257 3 6292
    regulation of programmed cell death 5.7106E-3 9 4 1 6292
    regulation of cell death 5.7106E-3 9 4 1 6292
    regulation of apoptosis 5.7106E-3 9 4 1 6292
    traversing start control point of mitotic cell cycle 8.5551E-3 9 6 1 6292
    cellular protein metabolic process 9.8781E-3 9 1074 5 6292
    response to exogenous dsRNA 9.9746E-3 9 7 1 6292
    response to dsRNA 9.9746E-3 9 7 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nucleic acid binding 8.7297E-5 9 666 6 6292
    translation initiation factor activity 6.2672E-4 9 27 2 6292
    translation factor activity, nucleic acid binding 1.6679E-3 9 44 2 6292
    structural constituent of ribosome 2.7255E-3 9 212 3 6292
    5'-3' exoribonuclease activity 2.859E-3 9 2 1 6292
    binding 3.5377E-3 9 1294 6 6292
    recombinase activity 5.7106E-3 9 4 1 6292
    5'-3' exonuclease activity 8.5551E-3 9 6 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle