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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Swi5. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 9 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ARP4
  • nucleus
  • nuclear chromatin
  • NuA4 histone acetyltransferase complex
  • Swr1 complex
  • Ino80 complex
  • DNA repair
  • chromatin remodeling
  • regulation of transcription, DNA-dependent
  • histone acetylation
  • chromatin organization
  • regulation of transcription from RNA polymerase II promoter
  • histone acetyltransferase activity
  • ATP-dependent 5'-3' DNA helicase activity
  • chromatin binding
  • FAA2
  • peroxisome
  • mitochondrion
  • lipid metabolic process
  • N-terminal protein myristoylation
  • long-chain fatty acid-CoA ligase activity
  • HFI1
  • SLIK (SAGA-like) complex
  • Ada2/Gcn5/Ada3 transcription activator complex
  • SAGA complex
  • chromatin modification
  • telomere maintenance
  • transcription from RNA polymerase II promoter
  • histone acetylation
  • transcription cofactor activity
  • transcription coactivator activity
  • RPO31
  • DNA-directed RNA polymerase III complex
  • transcription from RNA polymerase III promoter
  • DNA-directed RNA polymerase activity
  • SPT7
  • SLIK (SAGA-like) complex
  • mitochondrion
  • SAGA complex
  • chromatin modification
  • protein complex assembly
  • conjugation with cellular fusion
  • histone acetylation
  • structural molecule activity
  • STB4
  • nucleus
  • biological_process
  • DNA binding
  • SWC4
  • nucleus
  • NuA4 histone acetyltransferase complex
  • Swr1 complex
  • histone acetyltransferase complex
  • chromatin modification
  • DNA repair
  • chromatin remodeling
  • histone exchange
  • histone acetylation
  • DNA binding
  • SWI5
  • nucleus
  • cytoplasm
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription activator activity
  • TRA1
  • NuA4 histone acetyltransferase complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • histone acetyltransferase complex
  • DNA repair
  • histone acetylation
  • regulation of transcription from RNA polymerase II promoter
  • histone acetyltransferase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    histone acetyltransferase complex 1.6335E-9 9 44 5 6292
    nucleoplasm part 2.4983E-7 9 245 6 6292
    nucleoplasm 3.897E-7 9 264 6 6292
    H4/H2A histone acetyltransferase complex 7.3106E-7 9 14 3 6292
    NuA4 histone acetyltransferase complex 7.3106E-7 9 14 3 6292
    SLIK (SAGA-like) complex 1.1231E-6 9 16 3 6292
    SAGA complex 3.0753E-6 9 22 3 6292
    SAGA-type complex 3.534E-6 9 23 3 6292
    nuclear lumen 9.3951E-6 9 453 6 6292
    organelle lumen 8.2888E-5 9 660 6 6292
    intracellular organelle lumen 8.2888E-5 9 660 6 6292
    membrane-enclosed lumen 1.1604E-4 9 700 6 6292
    Swr1 complex 1.8916E-4 9 15 2 6292
    nucleus 7.7873E-4 9 2041 8 6292
    nuclear part 1.4854E-3 9 1103 6 6292
    protein complex 1.7541E-3 9 1137 6 6292
    nuclear chromatin 4.5346E-3 9 73 2 6292
    chromatin 5.0339E-3 9 77 2 6292
    Ada2/Gcn5/Ada3 transcription activator complex 7.1338E-3 9 5 1 6292
    chromatin remodeling complex 8.2102E-3 9 99 2 6292
    membrane-bounded organelle 9.9391E-3 9 3771 9 6292
    intracellular membrane-bounded organelle 9.9391E-3 9 3771 9 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein amino acid acylation 4.3076E-11 9 59 6 6292
    histone acetylation 5.6948E-10 9 36 5 6292
    protein amino acid acetylation 2.0596E-9 9 46 5 6292
    covalent chromatin modification 5.7558E-8 9 88 5 6292
    histone modification 5.7558E-8 9 88 5 6292
    chromatin modification 1.478E-6 9 168 5 6292
    chromatin organization 3.7747E-6 9 203 5 6292
    protein modification process 1.6502E-5 9 499 6 6292
    macromolecule modification 3.5308E-5 9 569 6 6292
    post-translational protein modification 5.9621E-5 9 357 5 6292
    transcription, DNA-dependent 3.0762E-4 9 503 5 6292
    RNA biosynthetic process 3.2237E-4 9 508 5 6292
    transcription 4.7709E-4 9 552 5 6292
    chromosome organization 4.8941E-4 9 555 5 6292
    transcription from RNA polymerase II promoter 8.0335E-4 9 335 4 6292
    cellular protein metabolic process 1.283E-3 9 1074 6 6292
    protein metabolic process 1.7457E-3 9 1136 6 6292
    cellular macromolecule metabolic process 1.8315E-3 9 2285 8 6292
    DNA repair 2.0512E-3 9 192 3 6292
    cellular macromolecule biosynthetic process 2.2182E-3 9 1187 6 6292
    macromolecule biosynthetic process 2.2386E-3 9 1189 6 6292
    macromolecule metabolic process 2.2547E-3 9 2349 8 6292
    regulation of transcription from RNA polymerase II promoter 3.3545E-3 9 228 3 6292
    response to DNA damage stimulus 3.7002E-3 9 236 3 6292
    chromatin remodeling 3.9454E-3 9 68 2 6292
    nucleic acid metabolic process 5.7023E-3 9 1415 6 6292
    RNA metabolic process 5.8652E-3 9 954 5 6292
    DNA metabolic process 6.3704E-3 9 585 4 6292
    cellular response to stress 6.6158E-3 9 290 3 6292
    protein myristoylation 7.1338E-3 9 5 1 6292
    N-terminal protein lipidation 7.1338E-3 9 5 1 6292
    N-terminal protein myristoylation 7.1338E-3 9 5 1 6292
    protein amino acid myristoylation 7.1338E-3 9 5 1 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 9.7168E-3 9 1566 6 6292
    cellular biosynthetic process 9.7492E-3 9 1567 6 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    histone acetyltransferase activity 2.4464E-4 9 17 2 6292
    lysine N-acetyltransferase activity 2.4464E-4 9 17 2 6292
    N-acetyltransferase activity 9.3856E-4 9 33 2 6292
    N-acyltransferase activity 1.245E-3 9 38 2 6292
    acetyltransferase activity 2.1502E-3 9 50 2 6292
    transcription activator activity 3.186E-3 9 61 2 6292
    transferase activity, transferring acyl groups other than amino-acyl groups 7.1217E-3 9 92 2 6292
    acyltransferase activity 7.1217E-3 9 92 2 6292
    long-chain fatty acid-CoA ligase activity 8.5551E-3 9 6 1 6292
    fatty acid ligase activity 8.5551E-3 9 6 1 6292
    transferase activity, transferring acyl groups 9.541E-3 9 107 2 6292
    ATP-dependent 5'-3' DNA helicase activity 9.9746E-3 9 7 1 6292

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