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Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 10 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ARP4
  • nucleus
  • nuclear chromatin
  • NuA4 histone acetyltransferase complex
  • Swr1 complex
  • Ino80 complex
  • DNA repair
  • chromatin remodeling
  • regulation of transcription, DNA-dependent
  • histone acetylation
  • chromatin organization
  • regulation of transcription from RNA polymerase II promoter
  • histone acetyltransferase activity
  • ATP-dependent 5'-3' DNA helicase activity
  • chromatin binding
  • ARP6
  • cytoplasm
  • Swr1 complex
  • chromatin remodeling
  • histone exchange
  • protein targeting to vacuole
  • nucleosome binding
  • BDF1
  • nucleus
  • nuclear chromatin
  • ascospore formation
  • DNA repair
  • chromatin remodeling
  • meiosis
  • transcription regulator activity
  • RVB1
  • nucleus
  • Swr1 complex
  • Ino80 complex
  • chromatin remodeling complex
  • chromatin remodeling
  • regulation of transcription from RNA polymerase II promoter
  • ATPase activity
  • ATP-dependent 5'-3' DNA helicase activity
  • RVB2
  • nucleus
  • Swr1 complex
  • Ino80 complex
  • nuclear outer membrane
  • chromatin remodeling complex
  • chromatin remodeling
  • snoRNA metabolic process
  • regulation of transcription from RNA polymerase II promoter
  • ATPase activity
  • ATP-dependent 5'-3' DNA helicase activity
  • SWC4
  • nucleus
  • NuA4 histone acetyltransferase complex
  • Swr1 complex
  • histone acetyltransferase complex
  • chromatin modification
  • DNA repair
  • chromatin remodeling
  • histone exchange
  • histone acetylation
  • DNA binding
  • SWC5
  • nucleus
  • Swr1 complex
  • chromatin remodeling
  • histone exchange
  • molecular_function
  • SWC7
  • nucleus
  • Swr1 complex
  • chromatin remodeling
  • molecular_function
  • SWR1
  • nucleus
  • Swr1 complex
  • chromatin remodeling
  • histone exchange
  • structural molecule activity
  • YAF9
  • nucleus
  • NuA4 histone acetyltransferase complex
  • cytoplasm
  • Swr1 complex
  • DNA repair
  • chromatin remodeling
  • histone exchange
  • chromatin silencing at telomere
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    Swr1 complex 1.1808E-24 10 15 9 6292
    nuclear chromatin 2.3351E-20 10 73 10 6292
    chromatin 4.1228E-20 10 77 10 6292
    chromatin remodeling complex 4.0348E-16 10 99 9 6292
    nuclear chromosome part 4.9904E-16 10 190 10 6292
    nuclear chromosome 3.2184E-15 10 228 10 6292
    chromosomal part 4.7766E-15 10 237 10 6292
    chromosome 2.092E-14 10 274 10 6292
    non-membrane-bounded organelle 6.5007E-9 10 959 10 6292
    intracellular non-membrane-bounded organelle 6.5007E-9 10 959 10 6292
    nuclear part 2.6498E-8 10 1103 10 6292
    DNA helicase complex 4.7397E-7 10 11 3 6292
    Ino80 complex 4.7397E-7 10 11 3 6292
    H4/H2A histone acetyltransferase complex 1.043E-6 10 14 3 6292
    NuA4 histone acetyltransferase complex 1.043E-6 10 14 3 6292
    protein complex 1.6785E-6 10 1137 9 6292
    nucleus 1.2708E-5 10 2041 10 6292
    histone acetyltransferase complex 3.7008E-5 10 44 3 6292
    intracellular organelle part 3.8887E-5 10 2282 10 6292
    organelle part 3.8887E-5 10 2282 10 6292
    macromolecular complex 4.0767E-5 10 1635 9 6292
    nucleoplasm part 5.7104E-3 10 245 3 6292
    membrane-bounded organelle 5.9511E-3 10 3771 10 6292
    intracellular membrane-bounded organelle 5.9511E-3 10 3771 10 6292
    nucleoplasm 7.0364E-3 10 264 3 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    chromatin remodeling 1.0927E-20 10 68 10 6292
    chromatin modification 1.4117E-16 10 168 10 6292
    chromatin organization 9.8259E-16 10 203 10 6292
    histone exchange 7.7142E-13 10 10 5 6292
    chromosome organization 2.6469E-11 10 555 10 6292
    ATP-dependent chromatin remodeling 1.9924E-10 10 26 5 6292
    nucleosome organization 3.5897E-10 10 29 5 6292
    organelle organization 3.289E-8 10 1127 10 6292
    cellular component organization 9.8834E-7 10 1582 10 6292
    cellular macromolecular complex subunit organization 2.4185E-5 10 259 5 6292
    macromolecular complex subunit organization 1.1371E-4 10 357 5 6292
    DNA repair 1.5279E-4 10 192 4 6292
    response to DNA damage stimulus 3.3899E-4 10 236 4 6292
    cellular response to stress 7.4443E-4 10 290 4 6292
    histone acetylation 1.3917E-3 10 36 2 6292
    regulation of transcription, DNA-dependent 1.6451E-3 10 358 4 6292
    regulation of RNA metabolic process 1.7325E-3 10 363 4 6292
    cellular response to stimulus 2.0342E-3 10 379 4 6292
    regulation of transcription 2.1357E-3 10 384 4 6292
    protein amino acid acetylation 2.267E-3 10 46 2 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.8459E-3 10 415 4 6292
    regulation of nitrogen compound metabolic process 2.8712E-3 10 416 4 6292
    regulation of gene expression 3.6771E-3 10 445 4 6292
    protein amino acid acylation 3.7066E-3 10 59 2 6292
    regulation of macromolecule biosynthetic process 4.0203E-3 10 456 4 6292
    regulation of cellular biosynthetic process 4.5583E-3 10 472 4 6292
    regulation of biosynthetic process 4.5935E-3 10 473 4 6292
    regulation of transcription from RNA polymerase II promoter 4.6649E-3 10 228 3 6292
    regulation of macromolecule metabolic process 5.1444E-3 10 488 4 6292
    response to stress 5.4959E-3 10 497 4 6292
    transcription, DNA-dependent 5.7393E-3 10 503 4 6292
    RNA biosynthetic process 5.9477E-3 10 508 4 6292
    regulation of primary metabolic process 6.2046E-3 10 514 4 6292
    regulation of cellular metabolic process 7.2118E-3 10 536 4 6292
    regulation of metabolic process 7.755E-3 10 547 4 6292
    transcription 8.0109E-3 10 552 4 6292
    covalent chromatin modification 8.0911E-3 10 88 2 6292
    histone modification 8.0911E-3 10 88 2 6292
    DNA metabolic process 9.8454E-3 10 585 4 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ATP-dependent 5'-3' DNA helicase activity 1.0088E-7 10 7 3 6292
    5'-3' DNA helicase activity 1.6127E-7 10 8 3 6292
    ATP-dependent DNA helicase activity 2.3303E-6 10 18 3 6292
    DNA helicase activity 1.6862E-5 10 34 3 6292
    ATP-dependent helicase activity 4.817E-5 10 48 3 6292
    purine NTP-dependent helicase activity 4.817E-5 10 48 3 6292
    DNA-dependent ATPase activity 7.2637E-5 10 55 3 6292
    helicase activity 2.4849E-4 10 83 3 6292
    chromatin binding 1.1694E-3 10 33 2 6292
    ATPase activity, coupled 1.3822E-3 10 149 3 6292
    nucleosome binding 3.1764E-3 10 2 1 6292
    ATPase activity 3.747E-3 10 211 3 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle