YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 17 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
BRX1
  • nucleolus
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • 5S rRNA binding
  • rRNA primary transcript binding
  • CIC1
  • proteasome complex
  • nucleolus
  • protein catabolic process
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • protein binding, bridging
  • DBP10
  • nuclear outer membrane
  • nucleolus
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • ATP-dependent RNA helicase activity
  • ERB1
  • nucleus
  • nucleolus
  • rRNA processing
  • molecular_function
  • FPR4
  • nucleus
  • chromatin
  • chromatin silencing at rDNA
  • negative regulation of histone H3-K36 methylation
  • ribosome biogenesis
  • histone peptidyl-prolyl isomerization
  • positive regulation of transcription from RNA polymerase II promoter
  • nucleosome assembly
  • peptidyl-prolyl cis-trans isomerase activity
  • histone binding
  • HAS1
  • nuclear envelope
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • RNA binding
  • RNA-dependent ATPase activity
  • ATP-dependent RNA helicase activity
  • MAK21
  • Noc1p-Noc2p complex
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • molecular_function
  • NIP7
  • nucleolus
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • rRNA processing
  • ribosomal large subunit assembly
  • molecular_function
  • NOC2
  • nucleus
  • Noc2p-Noc3p complex
  • mitochondrion
  • Noc1p-Noc2p complex
  • ribosomal subunit export from nucleus
  • ribosome biogenesis
  • ribosome assembly
  • molecular_function
  • NOC3
  • nucleus
  • Noc2p-Noc3p complex
  • nucleolus
  • DNA replication initiation
  • ribosome biogenesis
  • rRNA processing
  • protein binding
  • chromatin binding
  • NOG1
  • nuclear outer membrane
  • nucleolus
  • preribosome, large subunit precursor
  • ribosomal subunit export from nucleus
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • GTP binding
  • NOP2
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • RNA methyltransferase activity
  • S-adenosylmethionine-dependent methyltransferase activity
  • NUG1
  • nucleus
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • GTPase activity
  • PUF6
  • nucleus
  • nucleolus
  • regulation of transcription, mating-type specific
  • ribosome biogenesis
  • mRNA binding
  • specific transcriptional repressor activity
  • RLP7
  • nucleolus
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • processing of 27S pre-rRNA
  • rRNA binding
  • RPF1
  • nucleolus
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • processing of 27S pre-rRNA
  • rRNA primary transcript binding
  • SPB4
  • nuclear outer membrane
  • nucleolus
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • ATP-dependent RNA helicase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nucleolus 2.4015E-23 17 211 16 6292
    nuclear lumen 6.4547E-18 17 453 16 6292
    organelle lumen 2.7998E-15 17 660 16 6292
    intracellular organelle lumen 2.7998E-15 17 660 16 6292
    membrane-enclosed lumen 7.2058E-15 17 700 16 6292
    non-membrane-bounded organelle 1.1454E-14 17 959 17 6292
    intracellular non-membrane-bounded organelle 1.1454E-14 17 959 17 6292
    nuclear part 1.0341E-11 17 1103 16 6292
    preribosome, large subunit precursor 4.5585E-9 17 9 4 6292
    nucleus 4.6591E-9 17 2041 17 6292
    intracellular organelle part 3.129E-8 17 2282 17 6292
    organelle part 3.129E-8 17 2282 17 6292
    Noc complex 1.6332E-7 17 5 3 6292
    preribosome 1.6097E-6 17 34 4 6292
    Noc2p-Noc3p complex 6.8716E-6 17 2 2 6292
    Noc1p-Noc2p complex 6.8716E-6 17 2 2 6292
    membrane-bounded organelle 1.6371E-4 17 3771 17 6292
    intracellular membrane-bounded organelle 1.6371E-4 17 3771 17 6292
    nucleolar part 2.1677E-4 17 45 3 6292
    intracellular organelle 6.0057E-4 17 4070 17 6292
    organelle 6.0308E-4 17 4071 17 6292
    90S preribosome 9.1252E-4 17 17 2 6292
    nuclear outer membrane 1.4598E-3 17 86 3 6292
    nuclear envelope 1.6713E-3 17 199 4 6292
    nuclear membrane 2.0647E-3 17 97 3 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribosome biogenesis 2.6351E-22 17 346 17 6292
    ribonucleoprotein complex biogenesis 1.0198E-21 17 374 17 6292
    cellular component biogenesis 4.4392E-17 17 694 17 6292
    ribosomal large subunit biogenesis 1.7205E-14 17 65 9 6292
    ribosome assembly 1.445E-10 17 64 7 6292
    organelle assembly 2.4921E-10 17 69 7 6292
    ribosomal large subunit assembly 6.1408E-10 17 41 6 6292
    ribonucleoprotein complex assembly 1.9592E-9 17 92 7 6292
    ribosomal subunit assembly 3.8764E-9 17 55 6 6292
    cellular macromolecular complex assembly 8.1826E-9 17 182 8 6292
    cellular macromolecular complex subunit organization 1.304E-7 17 259 8 6292
    macromolecular complex assembly 2.453E-7 17 281 8 6292
    rRNA processing 6.4931E-7 17 128 6 6292
    rRNA metabolic process 9.7053E-7 17 137 6 6292
    macromolecular complex subunit organization 1.5381E-6 17 357 8 6292
    cellular component assembly 2.7265E-6 17 385 8 6292
    ncRNA processing 1.3402E-5 17 215 6 6292
    ncRNA metabolic process 3.7077E-5 17 257 6 6292
    RNA processing 3.2629E-4 17 380 6 6292
    processing of 27S pre-rRNA 8.0644E-4 17 16 2 6292
    RNA metabolic process 1.837E-3 17 954 8 6292
    establishment of ribosome localization 2.1497E-3 17 26 2 6292
    ribosome localization 2.1497E-3 17 26 2 6292
    ribosomal subunit export from nucleus 2.1497E-3 17 26 2 6292
    cellular process 2.5051E-3 17 4426 17 6292
    regulation of histone methylation 2.7018E-3 17 1 1 6292
    negative regulation of histone methylation 2.7018E-3 17 1 1 6292
    negative regulation of histone modification 2.7018E-3 17 1 1 6292
    regulation of histone modification 2.7018E-3 17 1 1 6292
    negative regulation of histone H3-K36 methylation 2.7018E-3 17 1 1 6292
    regulation of histone H3-K36 methylation 2.7018E-3 17 1 1 6292
    protein peptidyl-prolyl isomerization 2.7018E-3 17 1 1 6292
    histone peptidyl-prolyl isomerization 2.7018E-3 17 1 1 6292
    histone H3-K36 methylation 2.7018E-3 17 1 1 6292
    histone lysine methylation 5.3968E-3 17 2 1 6292
    regulation of chromosome organization 5.3968E-3 17 2 1 6292
    organelle organization 5.4383E-3 17 1127 8 6292
    establishment of organelle localization 9.3809E-3 17 55 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    rRNA binding 8.9795E-6 17 16 3 6292
    ATP-dependent RNA helicase activity 5.1487E-5 17 28 3 6292
    RNA-dependent ATPase activity 5.7332E-5 17 29 3 6292
    rRNA primary transcript binding 6.8389E-5 17 5 2 6292
    RNA helicase activity 1.7625E-4 17 42 3 6292
    ATP-dependent helicase activity 2.6289E-4 17 48 3 6292
    purine NTP-dependent helicase activity 2.6289E-4 17 48 3 6292
    helicase activity 1.3172E-3 17 83 3 6292
    RNA binding 2.267E-3 17 367 5 6292
    binding 3.1188E-3 17 1294 9 6292
    5S rRNA binding 5.3968E-3 17 2 1 6292
    ATPase activity, coupled 6.9354E-3 17 149 3 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle