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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 24 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
BMS1
  • nucleus
  • cytoplasm
  • mitochondrion
  • nuclear outer membrane
  • nucleolus
  • ribosome assembly
  • rRNA processing
  • GTP binding
  • DIP2
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • ECM16
  • mitochondrion
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • RNA helicase activity
  • EMG1
  • nucleus
  • cytoplasm
  • nuclear microtubule
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • IMP3
  • small-subunit processome
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • KRE33
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • MPP10
  • nucleus
  • small-subunit processome
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • NAN1
  • RENT complex
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • NOC4
  • nucleus
  • Noc4p-Nop14p complex
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • NOP1
  • nuclear outer membrane
  • nucleolus
  • ribosome
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • RNA methylation
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • snoRNA 3'-end processing
  • methyltransferase activity
  • NOP56
  • box C/D snoRNP complex
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • PWP2
  • cytoplasm
  • nuclear outer membrane
  • 90S preribosome
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • cytokinesis
  • ribosome biogenesis
  • snoRNA binding
  • SOF1
  • nuclear outer membrane
  • nucleolus
  • small nuclear ribonucleoprotein complex
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • snoRNA binding
  • UTP10
  • mitochondrion
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP13
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • snoRNA binding
  • UTP15
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP20
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • rRNA processing
  • snoRNA binding
  • UTP21
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosome biogenesis
  • snoRNA binding
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • UTP30
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • UTP4
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP6
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP7
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • UTP8
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    small nucleolar ribonucleoprotein complex 1.3563E-39 24 72 21 6292
    nuclear outer membrane 4.6379E-21 24 86 14 6292
    ribonucleoprotein complex 1.5664E-20 24 514 21 6292
    nuclear membrane 2.8111E-20 24 97 14 6292
    outer membrane 1.9345E-16 24 178 14 6292
    organelle outer membrane 1.9345E-16 24 178 14 6292
    nuclear envelope 9.4481E-16 24 199 14 6292
    nucleolus 2.1637E-15 24 211 14 6292
    nuclear membrane-endoplasmic reticulum network 8.2371E-15 24 232 14 6292
    endomembrane system 1.4407E-11 24 398 14 6292
    nuclear lumen 8.3205E-11 24 453 14 6292
    envelope 3.5813E-10 24 505 14 6292
    organelle envelope 3.5813E-10 24 505 14 6292
    macromolecular complex 4.045E-10 24 1635 21 6292
    organelle lumen 1.234E-8 24 660 14 6292
    intracellular organelle lumen 1.234E-8 24 660 14 6292
    nuclear part 1.2515E-8 24 1103 17 6292
    membrane part 1.2837E-8 24 662 14 6292
    organelle membrane 2.2865E-8 24 692 14 6292
    membrane-enclosed lumen 2.6546E-8 24 700 14 6292
    non-membrane-bounded organelle 1.4599E-6 24 959 14 6292
    intracellular non-membrane-bounded organelle 1.4599E-6 24 959 14 6292
    preribosome 6.9972E-6 24 34 4 6292
    membrane 2.2072E-5 24 1198 14 6292
    nucleus 1.283E-4 24 2041 17 6292
    small-subunit processome 2.0724E-4 24 6 2 6292
    intracellular organelle part 5.9532E-4 24 2282 17 6292
    organelle part 5.9532E-4 24 2282 17 6292
    nucleolar part 6.23E-4 24 45 3 6292
    90S preribosome 1.8314E-3 24 17 2 6292
    intracellular part 2.9448E-3 24 4938 24 6292
    intracellular 3.5241E-3 24 4975 24 6292
    box C/D snoRNP complex 7.6148E-3 24 2 1 6292
    Noc4p-Nop14p complex 7.6148E-3 24 2 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribosome biogenesis 2.7003E-31 24 346 24 6292
    maturation of SSU-rRNA 8.7954E-31 24 59 17 6292
    ribonucleoprotein complex biogenesis 1.8605E-30 24 374 24 6292
    rRNA processing 7.1407E-29 24 128 19 6292
    rRNA metabolic process 2.8413E-28 24 137 19 6292
    ncRNA processing 2.2823E-24 24 215 19 6292
    cellular component biogenesis 7.3464E-24 24 694 24 6292
    ncRNA metabolic process 7.5181E-23 24 257 19 6292
    RNA processing 1.4401E-19 24 380 19 6292
    RNA metabolic process 4.6235E-12 24 954 19 6292
    gene expression 1.0011E-9 24 1283 19 6292
    nucleic acid metabolic process 5.7516E-9 24 1415 19 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.4505E-8 24 1566 19 6292
    cellular nitrogen compound metabolic process 2.916E-7 24 1770 19 6292
    nitrogen compound metabolic process 3.5747E-7 24 1791 19 6292
    rRNA modification 4.8092E-7 24 18 4 6292
    cellular macromolecule metabolic process 2.1855E-5 24 2285 19 6292
    macromolecule metabolic process 3.4384E-5 24 2349 19 6292
    RNA modification 1.262E-4 24 70 4 6292
    cellular process 2.1149E-4 24 4426 24 6292
    primary metabolic process 9.4559E-4 24 2896 19 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.0602E-3 24 13 2 6292
    cellular metabolic process 1.8975E-3 24 3033 19 6292
    metabolic process 3.426E-3 24 3157 19 6292
    ribosomal small subunit biogenesis 4.2858E-3 24 26 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    snoRNA binding 5.3323E-31 24 31 15 6292
    RNA binding 1.8832E-13 24 367 15 6292
    nucleic acid binding 1.0609E-9 24 666 15 6292
    binding 1.2811E-6 24 1294 16 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle