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Protein Overview: RSC30

General Information:
Name(s) found: RSC30 / YHR056C [SGD]
Description(s) found:
Found 22 descriptions.
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  • Component of the RSC chromatin remodeling complex; non-essential gene required for regulation of ribosomal protein genes and the cell wall/stress response; highly similar to Rsc3p; null mutants are osmosensitive [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 883 amino acids

    Gene Ontology:
    Cellular Component: RSC complex [IDALink to PubMed article][IPILink to PubMed article]
    Biological Process: ATP-dependent chromatin remodeling [IDALink to PubMed article]
    regulation of transcription, DNA-dependent [IMPLink to PubMed article]
    double-strand break repair via nonhomologous end joining [IDALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: DNA binding [ISSLink to PubMed article]
    DNA-dependent ATPase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMDMQVRKVR KPPACTQCRK RKIGCDRAKP ICGNCVKYNK PDCFYPDGPG KMVAVPSASG  60
   61 MSTHGNGQGS NHFSQGNGVN QKNVMIQTQY PIMQTSIEAF NFSFNPSVDT AMQWTKAASY 120
  121 QNNNTNNNTA PRQNSSTVSS NVHGNTIVRS DSPDVPSMDQ IREYNTRLQL VNAQSFDYTD 180
  181 NPYSFNVGIN QDSAVFDLMT SPFTQEEVLI KEIDFLKNKL LDLQSLQLKS LKEKSNLNAD 240
  241 NTTANKINKT GENSKKGKVD GKRAGFDHQT SRTSQSSQKY FTALTITDVQ SLVQVKPLKD 300
  301 TPNYLFTKNF IIFRDHYLFK FYNILHDICH INQFKVSPPN NKNHQQYMEV CKVNFPPKAI 360
  361 IIETLNSESL NNLNIEEFLP IFDKTLLLEF VHNSFPNGDT CPSFSTVDLP LSQLTKLGEL 420
  421 TVLLLLLNDS MTLFNKQAIN NHVSALMNNL RLIRSQITLI NLEYYDQETI KFIAITKFYE 480
  481 SLYMHDDHKS SLDEDLSCLL SFQIKDFKLF HFLKKMYYSR HSLLGQSSFM VPAAENLSPI 540
  541 PASIDTNDIP LIANDLKLLE TQAKLINILQ GVPFYLPVNL TKIESLLETL TMGVSNTVDL 600
  601 YFHDNEVRKE WKDTLNFINT IVYTNFFLFV QNESSLSMAV QHSSNNNKTS NSERCAKDLM 660
  661 KIISNMHIFY SITFNFIFPI KSIKSFSSGN NRFHSNGKEF LFANHFIEIL QNFIAITFAI 720
  721 FQRCEVILYD EFYKNLSNEE INVQLLLIHD KILEILKKIE IIVSFLRDEM NSNGSFKSIK 780
  781 GFNKVLNLIK YMLRFSKKKQ NFARNSDNNN VTDYSQSAKN KNVLLKFPVS ELNRIYLKFK 840
  841 EISDFLMERE VVQRSIIIDK DLESDNLGIT TANFNDFYDA FYN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ARP7 ARP9 NPL6 RSC1 RSC2 RSC3 RSC30 RSC4 RSC58 RSC6 RSC8 RSC9 SFH1 STH1
    View Details Qiu et al. (2008) RSC1 RSC30 SFH1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen SPP382 RSC30 2 Hazbun TR, et al. (2003)

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..92] PSI-BLAST 6.09691 PPR1
    2 View Details [93..342] deduced N/A No confident structure predictions are available.
    3 View Details [343..539] deduced N/A No confident structure predictions are available.
    4 View Details [540..600] deduced N/A No confident structure predictions are available.
    5 View Details [601..883] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  4.56444258780502 bayes_pls_golite062009
  • DNA binding
    		•  4.26146437716972 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.17369933547911 bayes_pls_golite062009
  • transcription factor activity
    		•  3.049435548132 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.93914501897006 bayes_pls_golite062009
  • binding
    		•  2.91929847152301 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  2.44382866473054 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.87955444697212 bayes_pls_golite062009
  • transcription activator activity
    		•  0.915626626047549 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle