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Protein Overview: gi|15232736, gi|...

General Information:
Name(s) found: gi|6682244 [NCBI NR]
gi|15232736 [NCBI NR]
Description(s) found:
Found 10 descriptions.
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  • gi|6682244|gb|AAF23296.1|AC016661_21 putative minichromosome maintenance (MCM) protein [Arabidopsis thaliana] [NCBI NR]
  • gi|15232736|ref|NP_187577.1| MCM8; ATP binding / DNA binding / DNA-dependent ATPase/ nucleoside-triphosphatase/ nucleotide binding [Arabidopsis thaliana] [NCBI NR]
    • Organism: Arabidopsis thaliana
    Length: 777 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: DNA replication initiation [ISS]
    DNA replication [IEA]
    Molecular Function: nucleotide binding [IEA]
    DNA binding [IEA][ISS]
    ATP binding [IEA][ISS]
    DNA-dependent ATPase activity [ISS]
    nucleoside-triphosphatase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGFYGGGSMA SGRPESTGID SLGIGKILAV YIKDNENLAI DEDKLQLTAE LIRVFSASPG  60
   61 RDIVSQVNED GGGSFSLSLD LQQFKKISDI ENFFINLEDN PKGVIPCMNA AVHKVLFDQW 120
  121 ETNEFENVMK INVRLHNYPE SSISLKNLRA AYIGKLVTVH GTVVKVSTVK PLVTQMAFDC 180
  181 GKCKTGITRE FTDGKFSPPL KCDSHGCKSK TFTPIRSSAQ TIDFQKIRVQ ELQKPEDHEE 240
  241 GRVPRTVECE LMEDLVDICI PGDVVTVTGI IGVINNYMDI GGGKSKTKNQ GFYYLFIEAV 300
  301 SVKNTKRQSA FENSEDSSSS AQTADVGDLY SFSQRDLEFI VKFKEEYGSD TFRRILHSVC 360
  361 PSIYGHEIVK AGITLSLFGG VRKHSMDRNK VPVRGDIHVI IVGDPGLGKS QLLQAAAAIS 420
  421 PRGIYVCGNA TTRAGLTVAV VKDSMTNDYA FEAGAMVLAD GGLCCIDEFD KMTTEHQALL 480
  481 EAMEQQCVSV AKAGLVASLS ARTSVIAAAN PVGGHYNRAK TVNENLKMSA ALLSRFDLVF 540
  541 ILLDKPDELL DKQVSEHIMS HHRMLGMQTC MQKGILYFQD CGWTLRKMTT FLRFLANCLG 600
  601 NIFPMHGILM SKDAGEIIQK FYLKLRDHNT SADSTPITAR QLESLVRLAQ ARARVDLREE 660
  661 ITVQDAMDVV EIMKESLYDK LIDEHGVVDF GRSGGMSQQK EAKRFLSALD KQSELQQKDC 720
  721 FSVSEMYSLA DRIGLRVPDI DTFLENLNIA GYLLKKGPKT YQVLSSSYSR SQSSRSR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..252] PSI-BLAST 39.69897 DNA replication initiator (cdc21/cdc54) N-terminal domain
    2 View Details [253..347] PSI-BLAST 37.39794 Crystal structure of sigm54 activator (AAA+ ATPase) in the inactive state
    3 View Details [348..777] PSI-BLAST 27.69897 EDTA treated

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nucleic acid binding
    		•  3.99127970564994 bayes_pls_golite062009
  • DNA binding
    		•  3.53568546959418 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  3.06066809614422 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  3.0183551365402 bayes_pls_golite062009
  • binding
    		•  2.83465364476231 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.13063800565247 bayes_pls_golite062009
  • structural molecule activity
    		•  1.9177190829469 bayes_pls_golite062009
  • DNA replication origin binding
    		•  1.84819558112187 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.84350127337404 bayes_pls_golite062009
  • telomerase inhibitor activity
    		•  1.79151665830435 bayes_pls_golite062009
  • telomeric DNA binding
    		•  1.7847835613194 bayes_pls_golite062009
  • single-stranded telomeric DNA binding
    		•  1.48033977789232 bayes_pls_golite062009
  • DNA helicase activity
    		•  1.12203697857261 bayes_pls_golite062009
  • transcription factor activity
    		•  0.952569279670437 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.85691075793641 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  0.79554655100991 bayes_pls_golite062009
  • RNA polymerase activity
    		•  0.79554655100991 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.638831894247026 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.62994126331969 bayes_pls_golite062009
  • nuclease activity
    		•  0.57381531077345 bayes_pls_golite062009
  • translation regulator activity
    		•  0.515576958825022 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.468402630523277 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.325774164899685 bayes_pls_golite062009
  • exonuclease activity
    		•  0.28313884527829 bayes_pls_golite062009
  • translation initiation factor activity
    		•  0.2080607201312 bayes_pls_golite062009
  • protein binding
    		•  0.152645195799531 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.0954216620147701 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.0179535526984695 bayes_pls_golite062009
  • helicase activity
    		•  0.0121541775159524 bayes_pls_golite062009
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  6.53594658514943 bayes_pls_golite062009
  • DNA binding
    		•  4.23378162793777 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.98185277824074 bayes_pls_golite062009
  • transcription factor activity
    		•  3.46635567406922 bayes_pls_golite062009
  • signal transducer activity
    		•  3.29384659525629 bayes_pls_golite062009
  • molecular transducer activity
    		•  3.29384659525629 bayes_pls_golite062009
  • two-component response regulator activity
    		•  2.59441224418158 bayes_pls_golite062009
  • binding
    		•  2.56389923453102 bayes_pls_golite062009
    3
    Term Confidence Notes
  • DNA clamp loader activity
    		•  4.91429252297969 bayes_pls_golite062009
  • protein-DNA loading ATPase activity
    		•  4.80695929076807 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  2.72462789867829 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • DNA helicase activity
    		•  2.2817164193758 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.21184938313192 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.13284212711072 bayes_pls_golite062009
  • DNA binding
    		•  1.94055378599526 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  1.88455339138556 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.83584389083042 bayes_pls_golite062009
  • helicase activity
    		•  1.70242731830224 bayes_pls_golite062009
  • DNA replication origin binding
    		•  1.62491387774159 bayes_pls_golite062009
  • motor activity
    		•  1.34882329548339 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  0.971476020912368 bayes_pls_golite062009
  • DNA polymerase activity
    		•  0.928091843881235 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.782430219754236 bayes_pls_golite062009
  • transcription factor activity
    		•  0.697256579145077 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.6071273686445 bayes_pls_golite062009
  • microfilament motor activity
    		•  0.2184107989371 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.147579541298736 bayes_pls_golite062009
  • nucleotide binding
    		•  0.114848452385726 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.113504049290503 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.111293884322157 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.10713474095071 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.0916519414118148 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.0915913646217636 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.089234257580272 bayes_pls_golite062009
  • 3'-5' DNA helicase activity
    		•  0.0769112340058804 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle