YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: pef-1

General Information:
Name(s) found: pef-1 / CE27999 [WormBase]
Description(s) found:
Found 22 descriptions.
SHOW ALL
  • WBGene00003969 locus:pef-1 Serine\/threonine-protein phosphatase status:Confirmed UniProt:G5EBX9 protein_id:CCD69949.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 707 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    cytoplasm [IEALink to PubMed article]
    neuronal cell body [IDALink to PubMed article]
    Biological Process: detection of stimulus involved in sensory perception [IEALink to PubMed article]
    protein amino acid dephosphorylation [IEALink to PubMed article]
    Molecular Function: phosphoprotein phosphatase activity [IEALink to PubMed article]
    bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity [IEALink to PubMed article]
    iron ion binding [IEALink to PubMed article]
    calcium ion binding [IEALink to PubMed article]
    manganese ion binding [IEALink to PubMed article]
    hydrolase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGCGPSSGRQ NPSTELKKST RATTTTTSSS QRNNYNDNNQ NTSSSSGNKK ESSSSSKQHS  60
   61 SKKSKKSNSK KNRSPSPQPQ LTIKSAILIQ KWYRRCEARL EARRRATWQI FTALEYAGEQ 120
  121 DQLKLYDFFA DVIRAMAEEN GKGGVENGRN SPLMSALSHY AKPSLMDSEG ETVKKMLEDT 180
  181 SPTNVDIDRN YKGPTLSLPL DKPQVAKMIE AFKVNKVLHP KYVLMILHEA RKIFKAMPSV 240
  241 SRISTSISNQ VTICGDLHGK FDDLCIILYK NGYPSVDNPY IFNGDFVDRG GQSIEVLCVL 300
  301 FALVIVDPMS IYLNRGNHED HIMNLRYGFI KELSTKYKDL STPITRLLED VFSWLPIATI 360
  361 IDRDIFVVHG GISDQTEVSK LDKIPRHRFQ SVLRPPVNKG MESEKENSAV NVDEWKQMLD 420
  421 IMWSDPKQNK GCWPNVFRGG GSYFGADITA SFLEKHGFRL LVRSHECKFE GYEFSHNNTC 480
  481 LTVFSASNYY ETGSNRGAYV KFIGKSKQPH FVQYMASKTH RKSTLRERLG VVEESAVKEL 540
  541 KEKLSSFHTD LQKEFEIMDI EKSGKLPILK WSDCVERITG LNLPWIALAP KVATLSEDGK 600
  601 YVMYKEDRRI AQVGGTHAQE KDIVESLYRH KSTLETLFRF MDKDNSGQVS MKEFIDACEV 660
  661 LGKYTKRPLQ TDYISQIAES IDFNKDGFID LNELLEAFRL VDRPLLR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..532] PSI-BLAST 104.0 PP5 structure
    2 View Details [533..707] PSI-BLAST 30.0 Structure of calmodulin bound to a calcineurin peptide: a new way of making an old binding mode

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphoprotein phosphatase activity
    		•  11.6417995308386 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  10.6440947462013 bayes_pls_golite062009
  • phosphatase activity
    		•  10.5525832502704 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  10.3702645338723 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  9.02791306892273 bayes_pls_golite062009
  • calcium-dependent protein serine/threonine phosphatase activity
    		•  6.04386346716682 bayes_pls_golite062009
  • myosin phosphatase activity
    		•  5.31703100176823 bayes_pls_golite062009
  • hydrolase activity
    		•  3.13006743434485 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.36571535004008 bayes_pls_golite062009
  • DNA binding
    		•  1.95874073664777 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.72745783719415 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.68552051869632 bayes_pls_golite062009
  • kinase activity
    		•  1.67788383575784 bayes_pls_golite062009
  • structural molecule activity
    		•  1.5850868178597 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.57807175808088 bayes_pls_golite062009
  • protein kinase activity
    		•  1.4514460578232 bayes_pls_golite062009
  • binding
    		•  1.44538582463569 bayes_pls_golite062009
  • peptide binding
    		•  1.40475908899844 bayes_pls_golite062009
  • catalytic activity
    		•  1.39852585255405 bayes_pls_golite062009
  • transferase activity
    		•  1.3407391509244 bayes_pls_golite062009
  • protein binding
    		•  1.33435965029646 bayes_pls_golite062009
  • transporter activity
    		•  1.24767072239634 bayes_pls_golite062009
  • transcription factor activity
    		•  1.21805666483342 bayes_pls_golite062009
  • receptor activity
    		•  1.19949789380979 bayes_pls_golite062009
  • signal transducer activity
    		•  1.08090214431427 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.08090214431427 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.967526235944614 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.841959344808827 bayes_pls_golite062009
  • ligase activity
    		•  0.825764637499128 bayes_pls_golite062009
  • calmodulin binding
    		•  0.77173071932406 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.66803085638835 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  0.606264963283666 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.532407342912695 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.528189469950839 bayes_pls_golite062009
  • transcription factor binding
    		•  0.518146612491969 bayes_pls_golite062009
  • RNA binding
    		•  0.497066934302855 bayes_pls_golite062009
  • signal sequence binding
    		•  0.49295886046194 bayes_pls_golite062009
  • procollagen-proline dioxygenase activity
    		•  0.482467028485988 bayes_pls_golite062009
  • procollagen-proline 4-dioxygenase activity
    		•  0.482467028485988 bayes_pls_golite062009
  • peptidyl-proline 4-dioxygenase activity
    		•  0.482467028485988 bayes_pls_golite062009
  • peptidyl-proline dioxygenase activity
    		•  0.482467028485988 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  0.370858685623455 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.30464889749774 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.192538429095884 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.116119418380222 bayes_pls_golite062009
  • transcription activator activity
    		•  0.0593768116971065 bayes_pls_golite062009
  • small GTPase binding
    		•  0.0394561704024805 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.0274922636265745 bayes_pls_golite062009
  • acetyltransferase activity
    		•  0.0233291331884218 bayes_pls_golite062009
  • GTPase binding
    		•  0.0230090675760397 bayes_pls_golite062009
  • GTPase regulator activity
    		•  0.0182110291463968 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle