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Protein Overview: klp-20

General Information:
Name(s) found: klp-20 / CE26143 [WormBase]
Description(s) found:
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  • WBGene00002230 locus:klp-20 status:Confirmed UniProt:Q965T6 protein_id:CCD73793.1 [WormBase]
  • gi|17556094|ref|NP_497178.1| Kinesin-Like Protein family member (klp-20) [Caenorhabditis elegans] [NCBI NR]
  • gi|14574386|gb|AAK68513.1|AC024801_6 Kinesin-like protein protein 20 [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE26143 WBGene00002230 locus:klp-20 status:Confirmed TR:Q965T6 protein_id:AAK68513.1 [wormpep150.fasta]
  • 26143 WBGene00002230 locus:klp-20 status:Partially_confirmed TR:Q965T6 protein_id:AAK68513.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • kinesin-like protein (73.5 kD) (klp-20) [Caenorhabditis elegans]gi|14574386|gb|AAK68513.1| Kinesin-like protein protein 20 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE26143 WBGene00002230 locus:klp-20 status:Partially_confirmed TR:Q965T6 protein_id:AAK68513.1 [wormpep132.fasta]
  • 26143 WBGene00002230 locus:klp-20 status:Confirmed TR:Q965T6 protein_id:AAK68513.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • locus:klp-20 status:Partially_confirmed TR:Q965T6 protein_id:AAK68513.1 [wormpep115.fasta.reversed]
  • CE26143 status:Partially_confirmed TR:Q965T6 protein_id:AAK68513.1 [wormpep80.hongbin]
  • CE26143 WBGene00002230 locus:klp-20 status:Confirmed UniProt:Q965T6_CAEEL protein_id:AAK68513.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE26143 WBGene00002230 locus:klp-20 status:Confirmed UniProt:Q965T6_CAEEL protein_id:AAK68513.1| [wormORF-contam.fasta]
  • Kinesin-like protein protein 20 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Kinesin-Like Protein family member (klp-20) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE26143 WBGene00002230 locus:klp-20 status:Confirmed UniProt:Q965T6 protein_id:AAK68513.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • CE26143 WBGene00002230 locus:klp-20 status:Confirmed UniProt:Q965T6 protein_id:CCD73793.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE26143 WBGene00002230 locus:klp-20 status:Confirmed UniProt:Q965T6 protein_id:CCD73793.1 Kinesin-like protein [c_elegans-PRJNA13758-WS250-ecoli-contam.fasta]
  • Kinesin-like protein OS=Caenorhabditis elegans GN=klp-20 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 646 amino acids

    Gene Ontology:
    Cellular Component: microtubule associated complex [IEALink to PubMed article]
    Biological Process: microtubule-based movement [IEALink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    microtubule motor activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEGAEKVKVV VRCRPISTTE KLQGHKIAVT CNDEEKAVNI KSLSQEDPPR TFYFDAVFSP  60
   61 NTDQMTVYNV AARPIVENVL KGYNGTIFAY GQTGTGKTFT MAGDLEPVEM RGIIPNSFAH 120
  121 IFDHIAKCQH DTTFLVRVSY LEIYNEEIRD LLSKDHNGNL EIKERPDVGV YVRNLSNPTV 180
  181 ENASKMQALM EFGSKNRKVG ATAMNLESSR SHAMFTVTIE SCRNGLVTQG KLQLVDLAGS 240
  241 ERQSKTGAQG ERLKEAAKIN LSLSTLGNVI SSLVDGKSTH IPYRNSKLTR LLQDSLGGNS 300
  301 KTVMIANVGP ATYNYDETLS TLRYANRAKN IQNVAKINED PKDAQLRKFQ LEIEALRKIL 360
  361 DEENPGDDEN QEEAWEAKMQ EREVEMEKKR KILEERVNSA VNDEETHRLV KEMMENEAEL 420
  421 KKARSEHEKL RSKLEKIEKK LIVGGENLLE KVEEQAKLLE VNNKELEQSK FQEAHLRTQL 480
  481 EERTAVKVEI EERYSSLQEE AFVKSKKIKK VSNELKDARA ELKDLEEDHQ RQVEAMLDDI 540
  541 RQLRKELLLN IAIIDEYIPV EHVELIEKYV SWSEEHGDWQ LKAIAYTGNN MRASAPPAKK 600
  601 EFSNNNQTVP MYYSYRADLG ASTAEHRPRT SSKKHRASIR LQQLLT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..276] PSI-BLAST 90.0 Kinesin
    2 View Details [277..368] PSI-BLAST 10.69897 KINESIN (DIMERIC) FROM RATTUS NORVEGICUS
    3 View Details [369..646] PSI-BLAST 4.30103 Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain; Interferon-induced guanylate-binding protein 1 (GBP1), N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • microtubule motor activity
    		•  7.68336791348661 bayes_pls_golite062009
  • plus-end-directed microtubule motor activity
    		•  4.97507344344589 bayes_pls_golite062009
  • microfilament motor activity
    		•  4.176620576177 bayes_pls_golite062009
  • motor activity
    		•  4.04927796049806 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.95079405147356 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.87427509025394 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.85499564954033 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.85178667290149 bayes_pls_golite062009
  • actin-dependent ATPase activity
    		•  2.77140616759165 bayes_pls_golite062009
  • microtubule plus-end binding
    		•  2.71138928021716 bayes_pls_golite062009
  • tubulin binding
    		•  2.67743463093593 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • microtubule binding
    		•  2.59155206524122 bayes_pls_golite062009
  • transporter activity
    		•  2.58140740499725 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.4101693596493 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.39695871109024 bayes_pls_golite062009
  • ATPase activity
    		•  2.39535714892224 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.18396165590908 bayes_pls_golite062009
  • actin binding
    		•  1.75397031486306 bayes_pls_golite062009
  • hydrolase activity
    		•  1.57549510726226 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  1.4691865989136 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.40384549325664 bayes_pls_golite062009
  • helicase activity
    		•  1.33212695797068 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.29730375126024 bayes_pls_golite062009
  • protein binding
    		•  1.22129154759482 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.929901285538132 bayes_pls_golite062009
  • nucleotide binding
    		•  0.922442819194247 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.920987930180051 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.920926158369519 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.906554174337376 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.777787753097919 bayes_pls_golite062009
  • actin filament binding
    		•  0.728264616959762 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.620212706423176 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.55593847647213 bayes_pls_golite062009
  • kinetochore binding
    		•  0.505370954958131 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.49000746592281 bayes_pls_golite062009
  • DNA binding
    		•  0.479412476059825 bayes_pls_golite062009
  • GTPase activity
    		•  0.437665353870877 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.434775387083003 bayes_pls_golite062009
  • ATP binding
    		•  0.41092997612902 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.385813421701492 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.377870145186619 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.355466224802969 bayes_pls_golite062009
  • RNA helicase activity
    		•  0.34746349346164 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  0.328186246219424 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  0.328186246219424 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.312171320541728 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  0.30832907234141 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  0.29532978396745 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.294474570607914 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.282352478532746 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.25143870859482 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.25143870859482 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.220608508617331 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.219533217661421 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.219157471322311 bayes_pls_golite062009
  • protein transporter activity
    		•  0.178442534411253 bayes_pls_golite062009
  • signal transducer activity
    		•  0.0766574932313888 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.0766574932313888 bayes_pls_golite062009
  • minus-end-directed microtubule motor activity
    		•  0.068779631341469 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0254369227200564 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.0111338193708552 bayes_pls_golite062009
    2
    Term Confidence Notes
  • microtubule motor activity
    		•  7.68336791348661 bayes_pls_golite062009
  • plus-end-directed microtubule motor activity
    		•  4.97507344344589 bayes_pls_golite062009
  • microfilament motor activity
    		•  4.176620576177 bayes_pls_golite062009
  • motor activity
    		•  4.04927796049806 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.95079405147356 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.87427509025394 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.85499564954033 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.85178667290149 bayes_pls_golite062009
  • actin-dependent ATPase activity
    		•  2.77140616759165 bayes_pls_golite062009
  • microtubule plus-end binding
    		•  2.71138928021716 bayes_pls_golite062009
  • tubulin binding
    		•  2.67743463093593 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • microtubule binding
    		•  2.59155206524122 bayes_pls_golite062009
  • transporter activity
    		•  2.58140740499725 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.4101693596493 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.39695871109024 bayes_pls_golite062009
  • ATPase activity
    		•  2.39535714892224 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.18396165590908 bayes_pls_golite062009
  • actin binding
    		•  1.75397031486306 bayes_pls_golite062009
  • hydrolase activity
    		•  1.57549510726226 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  1.4691865989136 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.40384549325664 bayes_pls_golite062009
  • helicase activity
    		•  1.33212695797068 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.29730375126024 bayes_pls_golite062009
  • protein binding
    		•  1.22129154759482 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.929901285538132 bayes_pls_golite062009
  • nucleotide binding
    		•  0.922442819194247 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.920987930180051 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.920926158369519 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.906554174337376 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.777787753097919 bayes_pls_golite062009
  • actin filament binding
    		•  0.728264616959762 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.620212706423176 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.55593847647213 bayes_pls_golite062009
  • kinetochore binding
    		•  0.505370954958131 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.49000746592281 bayes_pls_golite062009
  • DNA binding
    		•  0.479412476059825 bayes_pls_golite062009
  • GTPase activity
    		•  0.437665353870877 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.434775387083003 bayes_pls_golite062009
  • ATP binding
    		•  0.41092997612902 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.385813421701492 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.377870145186619 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.355466224802969 bayes_pls_golite062009
  • RNA helicase activity
    		•  0.34746349346164 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  0.328186246219424 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  0.328186246219424 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.312171320541728 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  0.30832907234141 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  0.29532978396745 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.294474570607914 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.282352478532746 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.25143870859482 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.25143870859482 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.220608508617331 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.219533217661421 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.219157471322311 bayes_pls_golite062009
  • protein transporter activity
    		•  0.178442534411253 bayes_pls_golite062009
  • signal transducer activity
    		•  0.0766574932313888 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.0766574932313888 bayes_pls_golite062009
  • minus-end-directed microtubule motor activity
    		•  0.068779631341469 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0254369227200564 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.0111338193708552 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle