YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: klp-20
Organism: Caenorhabditis elegans
Length: 646 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for klp-20.

Description E-value Query
Range		 Subject
Range
gi|9800187 - gi|9800187|gb|AAF99087.1|AF149288_1 KRP85 [Caenorhabditis elegans]
 376.0 [0..4] [646..2]

Back

Predicted Domain #1
Region A:
Residues: [1-276] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEGAEKVKVV VRCRPISTTE KLQGHKIAVT CNDEEKAVNI KSLSQEDPPR TFYFDAVFSP  60
   61 NTDQMTVYNV AARPIVENVL KGYNGTIFAY GQTGTGKTFT MAGDLEPVEM RGIIPNSFAH 120
  121 IFDHIAKCQH DTTFLVRVSY LEIYNEEIRD LLSKDHNGNL EIKERPDVGV YVRNLSNPTV 180
  181 ENASKMQALM EFGSKNRKVG ATAMNLESSR SHAMFTVTIE SCRNGLVTQG KLQLVDLAGS 240
  241 ERQSKTGAQG ERLKEAAKIN LSLSTLGNVI SSLVDG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 90.0
Match: 1gojA
Description: Kinesin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
microtubule motor activity 7.68336791348661 bayes_pls_golite062009
plus-end-directed microtubule motor activity 4.97507344344589 bayes_pls_golite062009
microfilament motor activity 4.176620576177 bayes_pls_golite062009
motor activity 4.04927796049806 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.95079405147356 bayes_pls_golite062009
pyrophosphatase activity 2.87427509025394 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.85499564954033 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.85178667290149 bayes_pls_golite062009
actin-dependent ATPase activity 2.77140616759165 bayes_pls_golite062009
microtubule plus-end binding 2.71138928021716 bayes_pls_golite062009
tubulin binding 2.67743463093593 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
microtubule binding 2.59155206524122 bayes_pls_golite062009
transporter activity 2.58140740499725 bayes_pls_golite062009
cytoskeletal protein binding 2.4101693596493 bayes_pls_golite062009
transmembrane transporter activity 2.39695871109024 bayes_pls_golite062009
ATPase activity 2.39535714892224 bayes_pls_golite062009
ATPase activity, coupled 2.18396165590908 bayes_pls_golite062009
actin binding 1.75397031486306 bayes_pls_golite062009
hydrolase activity 1.57549510726226 bayes_pls_golite062009
ATP-dependent DNA helicase activity 1.4691865989136 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.40384549325664 bayes_pls_golite062009
helicase activity 1.33212695797068 bayes_pls_golite062009
substrate-specific transporter activity 1.29730375126024 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
purine nucleotide binding 0.929901285538132 bayes_pls_golite062009
nucleotide binding 0.922442819194247 bayes_pls_golite062009
purine ribonucleotide binding 0.920987930180051 bayes_pls_golite062009
ribonucleotide binding 0.920926158369519 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.906554174337376 bayes_pls_golite062009
nucleic acid binding 0.777787753097919 bayes_pls_golite062009
actin filament binding 0.728264616959762 bayes_pls_golite062009
structure-specific DNA binding 0.620212706423176 bayes_pls_golite062009
DNA-dependent ATPase activity 0.55593847647213 bayes_pls_golite062009
kinetochore binding 0.505370954958131 bayes_pls_golite062009
double-stranded DNA binding 0.49000746592281 bayes_pls_golite062009
DNA binding 0.479412476059825 bayes_pls_golite062009
GTPase activity 0.437665353870877 bayes_pls_golite062009
active transmembrane transporter activity 0.434775387083003 bayes_pls_golite062009
ATP binding 0.41092997612902 bayes_pls_golite062009
adenyl ribonucleotide binding 0.385813421701492 bayes_pls_golite062009
adenyl nucleotide binding 0.377870145186619 bayes_pls_golite062009
ion transmembrane transporter activity 0.355466224802969 bayes_pls_golite062009
RNA helicase activity 0.34746349346164 bayes_pls_golite062009
histone acetyltransferase activity 0.328186246219424 bayes_pls_golite062009
lysine N-acetyltransferase activity 0.328186246219424 bayes_pls_golite062009
transcription regulator activity 0.312171320541728 bayes_pls_golite062009
ATP-dependent RNA helicase activity 0.30832907234141 bayes_pls_golite062009
RNA-dependent ATPase activity 0.29532978396745 bayes_pls_golite062009
primary active transmembrane transporter activity 0.294474570607914 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.282352478532746 bayes_pls_golite062009
ATP-dependent helicase activity 0.25143870859482 bayes_pls_golite062009
purine NTP-dependent helicase activity 0.25143870859482 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.220608508617331 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.219533217661421 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.219157471322311 bayes_pls_golite062009
protein transporter activity 0.178442534411253 bayes_pls_golite062009
signal transducer activity 0.0766574932313888 bayes_pls_golite062009
molecular transducer activity 0.0766574932313888 bayes_pls_golite062009
minus-end-directed microtubule motor activity 0.068779631341469 bayes_pls_golite062009
cation transmembrane transporter activity 0.0254369227200564 bayes_pls_golite062009
structural constituent of cytoskeleton 0.0111338193708552 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [277-368] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSTHIPYRNS KLTRLLQDSL GGNSKTVMIA NVGPATYNYD ETLSTLRYAN RAKNIQNVAK  60
   61 INEDPKDAQL RKFQLEIEAL RKILDEENPG DD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.69897
Match: 3kinB
Description: KINESIN (DIMERIC) FROM RATTUS NORVEGICUS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
microtubule motor activity 7.68336791348661 bayes_pls_golite062009
plus-end-directed microtubule motor activity 4.97507344344589 bayes_pls_golite062009
microfilament motor activity 4.176620576177 bayes_pls_golite062009
motor activity 4.04927796049806 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.95079405147356 bayes_pls_golite062009
pyrophosphatase activity 2.87427509025394 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.85499564954033 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.85178667290149 bayes_pls_golite062009
actin-dependent ATPase activity 2.77140616759165 bayes_pls_golite062009
microtubule plus-end binding 2.71138928021716 bayes_pls_golite062009
tubulin binding 2.67743463093593 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
microtubule binding 2.59155206524122 bayes_pls_golite062009
transporter activity 2.58140740499725 bayes_pls_golite062009
cytoskeletal protein binding 2.4101693596493 bayes_pls_golite062009
transmembrane transporter activity 2.39695871109024 bayes_pls_golite062009
ATPase activity 2.39535714892224 bayes_pls_golite062009
ATPase activity, coupled 2.18396165590908 bayes_pls_golite062009
actin binding 1.75397031486306 bayes_pls_golite062009
hydrolase activity 1.57549510726226 bayes_pls_golite062009
ATP-dependent DNA helicase activity 1.4691865989136 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.40384549325664 bayes_pls_golite062009
helicase activity 1.33212695797068 bayes_pls_golite062009
substrate-specific transporter activity 1.29730375126024 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
purine nucleotide binding 0.929901285538132 bayes_pls_golite062009
nucleotide binding 0.922442819194247 bayes_pls_golite062009
purine ribonucleotide binding 0.920987930180051 bayes_pls_golite062009
ribonucleotide binding 0.920926158369519 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.906554174337376 bayes_pls_golite062009
nucleic acid binding 0.777787753097919 bayes_pls_golite062009
actin filament binding 0.728264616959762 bayes_pls_golite062009
structure-specific DNA binding 0.620212706423176 bayes_pls_golite062009
DNA-dependent ATPase activity 0.55593847647213 bayes_pls_golite062009
kinetochore binding 0.505370954958131 bayes_pls_golite062009
double-stranded DNA binding 0.49000746592281 bayes_pls_golite062009
DNA binding 0.479412476059825 bayes_pls_golite062009
GTPase activity 0.437665353870877 bayes_pls_golite062009
active transmembrane transporter activity 0.434775387083003 bayes_pls_golite062009
ATP binding 0.41092997612902 bayes_pls_golite062009
adenyl ribonucleotide binding 0.385813421701492 bayes_pls_golite062009
adenyl nucleotide binding 0.377870145186619 bayes_pls_golite062009
ion transmembrane transporter activity 0.355466224802969 bayes_pls_golite062009
RNA helicase activity 0.34746349346164 bayes_pls_golite062009
histone acetyltransferase activity 0.328186246219424 bayes_pls_golite062009
lysine N-acetyltransferase activity 0.328186246219424 bayes_pls_golite062009
transcription regulator activity 0.312171320541728 bayes_pls_golite062009
ATP-dependent RNA helicase activity 0.30832907234141 bayes_pls_golite062009
RNA-dependent ATPase activity 0.29532978396745 bayes_pls_golite062009
primary active transmembrane transporter activity 0.294474570607914 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.282352478532746 bayes_pls_golite062009
ATP-dependent helicase activity 0.25143870859482 bayes_pls_golite062009
purine NTP-dependent helicase activity 0.25143870859482 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.220608508617331 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.219533217661421 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.219157471322311 bayes_pls_golite062009
protein transporter activity 0.178442534411253 bayes_pls_golite062009
signal transducer activity 0.0766574932313888 bayes_pls_golite062009
molecular transducer activity 0.0766574932313888 bayes_pls_golite062009
minus-end-directed microtubule motor activity 0.068779631341469 bayes_pls_golite062009
cation transmembrane transporter activity 0.0254369227200564 bayes_pls_golite062009
structural constituent of cytoskeleton 0.0111338193708552 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [369-646] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENQEEAWEAK MQEREVEMEK KRKILEERVN SAVNDEETHR LVKEMMENEA ELKKARSEHE  60
   61 KLRSKLEKIE KKLIVGGENL LEKVEEQAKL LEVNNKELEQ SKFQEAHLRT QLEERTAVKV 120
  121 EIEERYSSLQ EEAFVKSKKI KKVSNELKDA RAELKDLEED HQRQVEAMLD DIRQLRKELL 180
  181 LNIAIIDEYI PVEHVELIEK YVSWSEEHGD WQLKAIAYTG NNMRASAPPA KKEFSNNNQT 240
  241 VPMYYSYRAD LGASTAEHRP RTSSKKHRAS IRLQQLLT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.30103
Match: 1dg3A
Description: Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain; Interferon-induced guanylate-binding protein 1 (GBP1), N-terminal domain
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle