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Protein Overview: cyp-33C11

General Information:
Name(s) found: cyp-33C11 / CE22218 [WormBase]
Description(s) found:
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  • WBGene00021710 locus:cyp-33C11 status:Partially_confirmed UniProt:Q965T7 protein_id:CCD72464.1 [WormBase]
  • gi|17565874|ref|NP_503303.1| CYtochrome P450 family member (cyp-33C11) [Caenorhabditis elegans] [NCBI NR]
  • gi|14702126|gb|AAK72319.1|AC024799_8 Cytochrome p450 family protein 33C11 [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE22218 WBGene00021710 locus:cyp-33C11 status:Partially_confirmed TR:Q965T7 protein_id:AAK72319.1 [wormpep150.fasta]
  • 22218 WBGene00021710 status:Partially_confirmed TR:Q965T7 protein_id:AAK72319.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • cytochrome P450 2c3 precursor family member (5B190) [Caenorhabditis elegans]gi|14702126|gb|AAK72319.1| Hypothetical protein Y49C4A.9 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE22218 WBGene00021710 status:Partially_confirmed TR:Q965T7 protein_id:AAK72319.1 [wormpep132.fasta]
  • 22218 WBGene00021710 locus:cyp-33C11 status:Partially_confirmed TR:Q965T7 protein_id:AAK72319.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • status:Partially_confirmed TR:Q965T7 protein_id:AAK72319.1 [wormpep115.fasta.reversed]
  • CE22218 status:Predicted TR:Q965T7 protein_id:AAK72319.1 [wormpep80.hongbin]
  • CE22218 WBGene00021710 locus:cyp-33C11 status:Partially_confirmed UniProt:Q965T7_CAEEL protein_id:AAK72319.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE22218 WBGene00021710 locus:cyp-33C11 status:Partially_confirmed UniProt:Q965T7_CAEEL protein_id:AAK72319.1| [wormORF-contam.fasta]
  • Cytochrome p450 family protein 33C11 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CYtochrome P450 family member (cyp-33C11) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE22218 WBGene00021710 locus:cyp-33C11 status:Partially_confirmed UniProt:Q965T7 protein_id:AAK72319.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • CE22218 WBGene00021710 locus:cyp-33C11 status:Partially_confirmed UniProt:Q965T7 protein_id:CCD72464.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE22218 WBGene00021710 locus:cyp-33C11 status:Partially_confirmed UniProt:Q965T7 protein_id:CCD72464.1 Cytochrome P450 family [wormpep246-ecoli-contam.fasta]
  • CYtochrome P450 family OS=Caenorhabditis elegans GN=cyp-33c11 PE=3 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 495 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEALink to PubMed article]
    Biological Process: electron transport [IEALink to PubMed article]
    Molecular Function: iron ion binding [IEALink to PubMed article]
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [IEALink to PubMed article]
    monooxygenase activity [IEALink to PubMed article]
    heme binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIAFSIFIAI FFWLAHCFYF KRRNLPPGPT PLPFLGNSLS MIWENPGYEC FRRWTRIYGD  60
   61 VFTFWLGDTP YVVISSLEKM KETFIKDGET YQDKIQFSFT EKFRGGRFGV IETTGHMWST 120
  121 HRRFAISTFR DLGLGKNLMQ EKILAEVEAV FQILDANLGA EQDVPEVIYN AVANVINQMI 180
  181 FGYRFDESNQ NEFEKLKDLI DIQEKSFASF KLCVQAFVPI MNKLLPGKSL EDLIAEKRHD 240
  241 YYNFFYAQIQ DHRAKINYQA EEYLDYAEAY LKEQKNQEQG GLGSDLFSDQ QLANMCFDLW 300
  301 FAGLTTTNTT INWTISYVLN HPEVQDKMQE ELDKVVGSDR LVTISDKSSL PYMNAVINES 360
  361 QRCVNLLPCN LFHATTRDTV INGNIIPKGT GVIAQISTVM LDEKIFPDPY KFQPERFIDE 420
  421 NGALKKIEQL IPFSVGKRQC LGEGLARMEL FLIVANLFNR YFITPSSAGP PSLERTEMVG 480
  481 VFPRKFQAIL TRRYE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..495] PSI-BLAST 108.0 Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • arachidonic acid monooxygenase activity
    		•  6.76823710927794 bayes_pls_golite062009
  • fatty acid (omega-1)-hydroxylase activity
    		•  6.3313834755701 bayes_pls_golite062009
  • monooxygenase activity
    		•  5.57229509004705 bayes_pls_golite062009
  • steroid hydroxylase activity
    		•  5.04794778387361 bayes_pls_golite062009
  • arachidonic acid epoxygenase activity
    		•  4.80764258881036 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
    		•  4.64322346579269 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
    		•  3.68151610133025 bayes_pls_golite062009
  • demethylase activity
    		•  3.40807632433846 bayes_pls_golite062009
  • oxygen binding
    		•  3.29945075872446 bayes_pls_golite062009
  • sterol 14-demethylase activity
    		•  2.94610675710811 bayes_pls_golite062009
  • retinoic acid 4-hydroxylase activity
    		•  2.60901411823382 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
    		•  2.56821164444595 bayes_pls_golite062009
  • oxysterol 7-alpha-hydroxylase activity
    		•  2.36480328243514 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.35847923992364 bayes_pls_golite062009
  • steroid 7-alpha-hydroxylase activity
    		•  2.21042366294727 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
    		•  2.15105968497418 bayes_pls_golite062009
  • steroid 17-alpha-monooxygenase activity
    		•  2.036553099796 bayes_pls_golite062009
  • ecdysteroid 25-hydroxylase activity
    		•  2.0071742914584 bayes_pls_golite062009
  • retinoid binding
    		•  1.91237853759594 bayes_pls_golite062009
  • vitamin D 24-hydroxylase activity
    		•  1.81919676974797 bayes_pls_golite062009
  • isoprenoid binding
    		•  1.78853880472253 bayes_pls_golite062009
  • flavonoid 3'-monooxygenase activity
    		•  1.71233606135238 bayes_pls_golite062009
  • vitamin D3 25-hydroxylase activity
    		•  1.65825585934141 bayes_pls_golite062009
  • vitamin D 25-hydroxylase activity
    		•  1.65825585934141 bayes_pls_golite062009
  • retinoic acid binding
    		•  1.55035199545719 bayes_pls_golite062009
  • electron carrier activity
    		•  1.48516712188486 bayes_pls_golite062009
  • arachidonic acid 11,12-epoxygenase activity
    		•  1.48500938886158 bayes_pls_golite062009
  • testosterone 6-beta-hydroxylase activity
    		•  1.4661447981611 bayes_pls_golite062009
  • corticosterone 18-monooxygenase activity
    		•  1.4105861338158 bayes_pls_golite062009
  • steroid 11-beta-monooxygenase activity
    		•  1.4105861338158 bayes_pls_golite062009
  • binding
    		•  1.0881336564542 bayes_pls_golite062009
  • 25-hydroxycholecalciferol-24-hydroxylase activity
    		•  1.06487564122685 bayes_pls_golite062009
  • ecdysteroid 22-hydroxylase activity
    		•  0.7601272997427 bayes_pls_golite062009
  • catalytic activity
    		•  0.608111453189583 bayes_pls_golite062009
  • cholesterol monooxygenase (side-chain-cleaving) activity
    		•  0.276594551871869 bayes_pls_golite062009
  • 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity
    		•  0.203772707673481 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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