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Protein Overview: cyp-33C12

General Information:
Name(s) found: cyp-33C12 / CE21315 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00021168 locus:cyp-33C12 status:Confirmed UniProt:Q9N4Q4 protein_id:CCD67437.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 426 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: electron transport [IEALink to PubMed article]
    Molecular Function: iron ion binding [IEALink to PubMed article]
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [IEALink to PubMed article]
    monooxygenase activity [IEALink to PubMed article]
    heme binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLLLFLSVL FLALFYEFHW KRRNYPAGPL PLPVIGNMWS MMRNNSGVEC FRQWTKDFGD  60
   61 VYTFWFGTKP YIVVSSYKRL KEAFILDGDT FADKIRQPFQ DQFRGGNYGV VDTNGHVWST 120
  121 HRRFALSSFR DFGLGKNLLQ EKMLIEVQDM FAKFDANLGK EQNLPVVLYN AAANVINQLI 180
  181 FGYRFDKERE GELKKLKALM EFQETAFTTF KVYVQFFAPA IGKHLPGKSV EDLLAEFTVD 240
  241 FYKFFNHQIE EHRSKIDFDS EESLDYAEAY LKEQRKQEAQ GEFELFSTKQ LSNTCFDLWF 300
  301 AGLSTTHITL TWIVGHVLNY PDVQRKLHKE LDEVIGSDRL ITNDDKNNLP YLNAVINESQ 360
  361 RCANIVPINQ IHSTSRDTVI NGITVKKGTG VIPQISAIML DDKVFPDPYA FNPERFLDAN 420
  421 GKLRKI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..426] PSI-BLAST 89.39794 Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • monooxygenase activity
    		•  5.57229509004705 bayes_pls_golite062009
  • steroid hydroxylase activity
    		•  5.04794778387361 bayes_pls_golite062009
  • steroid 17-alpha-monooxygenase activity
    		•  3.99744233006162 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
    		•  3.24344797738248 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
    		•  2.41884363121524 bayes_pls_golite062009
  • oxysterol 7-alpha-hydroxylase activity
    		•  2.36480328243514 bayes_pls_golite062009
  • arachidonic acid monooxygenase activity
    		•  2.35162461983176 bayes_pls_golite062009
  • sterol 14-demethylase activity
    		•  2.33937429425924 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.31118630300684 bayes_pls_golite062009
  • retinoic acid 4-hydroxylase activity
    		•  2.27465774301343 bayes_pls_golite062009
  • oxygen binding
    		•  1.94999422900255 bayes_pls_golite062009
  • demethylase activity
    		•  1.89119521471262 bayes_pls_golite062009
  • steroid 7-alpha-hydroxylase activity
    		•  1.85401713490512 bayes_pls_golite062009
  • corticosterone 18-monooxygenase activity
    		•  1.64204907906991 bayes_pls_golite062009
  • steroid 11-beta-monooxygenase activity
    		•  1.64204907906991 bayes_pls_golite062009
  • retinoid binding
    		•  1.55427837836259 bayes_pls_golite062009
  • electron carrier activity
    		•  1.48516712188486 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
    		•  1.46109575978397 bayes_pls_golite062009
  • isoprenoid binding
    		•  1.43053384013166 bayes_pls_golite062009
  • retinoic acid binding
    		•  1.21667685596765 bayes_pls_golite062009
  • binding
    		•  1.0881336564542 bayes_pls_golite062009
  • fatty acid (omega-1)-hydroxylase activity
    		•  0.979631262400031 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
    		•  0.912493861244809 bayes_pls_golite062009
  • arachidonic acid epoxygenase activity
    		•  0.75181432044872 bayes_pls_golite062009
  • catalytic activity
    		•  0.608111453189583 bayes_pls_golite062009
  • cholesterol monooxygenase (side-chain-cleaving) activity
    		•  0.276594551871869 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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