YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: hsd-1

General Information:
Name(s) found: hsd-1 / CE20185 [WormBase]
Description(s) found:
Found 19 descriptions.
SHOW ALL
  • WBGene00012394 locus:hsd-1 status:Predicted UniProt:Q9XWF0 protein_id:CAA21722.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 462 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEALink to PubMed article]
    Biological Process: carbohydrate metabolic process [IEALink to PubMed article]
    steroid biosynthetic process [IEALink to PubMed article]
    galactose metabolic process [IEALink to PubMed article]
    cellular metabolic process [IEALink to PubMed article]
    Molecular Function: 3-beta-hydroxy-delta5-steroid dehydrogenase activity [IEALink to PubMed article]
    NADP or NADPH binding [IEALink to PubMed article]
    coenzyme binding [IEALink to PubMed article]
    catalytic activity [IEALink to PubMed article]
    UDP-glucose 4-epimerase activity [IEALink to PubMed article]
    steroid delta-isomerase activity [IEALink to PubMed article]
    ADP-glyceromanno-heptose 6-epimerase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIKRLSMRL KKGIHRSWNR MTSLEAGLEE EKEIKIVEEP EPRPWKVLIT GGAGHLAENL  60
   61 VAKLEEMTRD SIRPKIREML EKEMPAVIST KVDKEVEKRL PMYIQIVLVD VLEPRGRVLK 120
  121 HHVAFVKCSF DDECTMKTAL EQVDTVYHLA AVGMTGQYAR DRKACMDINA VGTMNLLIWA 180
  181 RNSGVQRFIY TSSVGVVFSG EPMYNATEEV GYPDDFYNYY CESKAHAERI VQKASGHRMR 240
  241 TTVLRFNGIY GPGEKRVTER VVKFMLTGMW IATCKPNGVE AQTQLSSVAN CIQGLVKAEL 300
  301 ALRWSDTPHG QIYNIMDKTP VGTFSFWTPL NIALGFSSSM ITVPATPIRL FAYLSQIIAD 360
  361 RMRIDPIVSV LEVDLLLVNN TFNIEKAERD LGYEPSVSAI PEIIEHYLHR LPPDVVRPKG 420
  421 RSDFYVKVAV LVLGTILIFV AVFSFTFWMY LIFQRLSRWN PF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..462] PSI-BLAST 62.39794 Crystal structure of the gal10 fusion protein galactose mutarotase/UDP-galactose 4-epimerase from Saccharomyces cerevisiae complexed with NAD, UDP-glucose, and galactose

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • steroid dehydrogenase activity
    		•  3.70115036051018 bayes_pls_golite062009
  • steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  3.56748749904419 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  3.08644105481774 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  2.27417613545298 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.97774592602866 bayes_pls_golite062009
  • 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity
    		•  1.80383455383329 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • ethanol binding
    		•  1.43137718523288 bayes_pls_golite062009
  • retinol binding
    		•  1.36627553306209 bayes_pls_golite062009
  • C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
    		•  1.03845584151228 bayes_pls_golite062009
  • DNA binding
    		•  0.925435782369235 bayes_pls_golite062009
  • receptor activity
    		•  0.870552554168634 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.848495583450678 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.830735196151903 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.805690663404413 bayes_pls_golite062009
  • benzaldehyde dehydrogenase activity
    		•  0.74738022559788 bayes_pls_golite062009
  • retinoid binding
    		•  0.67821643688355 bayes_pls_golite062009
  • alcohol dehydrogenase (NAD) activity
    		•  0.65743456407889 bayes_pls_golite062009
  • signal transducer activity
    		•  0.620476349006324 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.620476349006324 bayes_pls_golite062009
  • 11-beta-hydroxysteroid dehydrogenase activity
    		•  0.617411823427239 bayes_pls_golite062009
  • isoprenoid binding
    		•  0.56322670082984 bayes_pls_golite062009
  • binding
    		•  0.553666136934364 bayes_pls_golite062009
  • testosterone 17-beta-dehydrogenase activity
    		•  0.532187027260366 bayes_pls_golite062009
  • coenzyme binding
    		•  0.46570602169425 bayes_pls_golite062009
  • NAD or NADH binding
    		•  0.44922383360529 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.39101464838432 bayes_pls_golite062009
  • transcription factor activity
    		•  0.288669328257774 bayes_pls_golite062009
  • all-trans retinal binding
    		•  0.218888750914841 bayes_pls_golite062009
  • NADPH:quinone reductase activity
    		•  0.0435917990586205 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle