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Catalysis of the reaction: an 11-beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+. Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative. Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD(P)+ = an 11-oxosteroid + NAD(P)H + H+. Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 11-beta-hydroxysteroid dehydrogenase activity
Acc: GO:0003845
Aspect: Molecular Function
Desc: Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD(P)+ = an 11-oxosteroid + NAD(P)H + H+.
Synonyms:
  • beta-hydroxysteroid dehydrogenase
  • 11beta-hydroxy steroid dehydrogenase
  • 11beta-hydroxysteroid dehydrogenase
  • corticosteroid 11-reductase
  • dehydrogenase, 11beta-hydroxy steroid
  • corticosteroid 11beta-dehydrogenase
Proteins in PDR annotated with:
   This term: 7 [Search]
   Term or descendants: 7 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0003845 - 11-beta-hydroxysteroid dehydrogenase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle