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Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative. Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative. Catalysis of the reaction: 3-beta-hydroxy-delta(5)-steroid + NAD+ = 3-oxo-delta(5)-steroid + NADH + H+. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 3-beta-hydroxy-delta5-steroid dehydrogenase activity
Acc: GO:0003854
Aspect: Molecular Function
Desc: Catalysis of the reaction: 3-beta-hydroxy-delta(5)-steroid + NAD+ = 3-oxo-delta(5)-steroid + NADH + H+.
Synonyms:
  • 5-ene-3-beta-hydroxysteroid dehydrogenase activity
  • steroid-delta5-3beta-ol dehydrogenase activity
  • 3beta-hydroxy-delta5-C27-steroid dehydrogenase/isomerase activity
  • 3beta-HSDH
  • 3beta-hydroxy steroid dehydrogenase/isomerase activity
  • progesterone reductase activity
  • 3beta-hydroxy-5-ene steroid dehydrogenase activity
  • 3beta-hydroxy-delta5-C27-steroid oxidoreductase
  • 3beta-hydroxy-5-ene-steroid oxidoreductase activity
  • 3-beta-hydroxy-5-ene steroid dehydrogenase activity
  • 3beta-hydroxy-5-ene-steroid dehydrogenase activity
  • 3-beta-hydroxy-D5-steroid dehydrogenase activity
  • 3beta-hydroxy-delta5-steroid dehydrogenase activity
  • delta5-3beta-hydroxysteroid dehydrogenase activity
  • 3beta-hydroxy-delta5-steroid:NAD+ 3-oxidoreductase activity
Proteins in PDR annotated with:
   This term: 41 [Search]
   Term or descendants: 41 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0003854 - 3-beta-hydroxy-delta5-steroid dehydrogenase activity (interactive image map)
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