| Protein: | hsd-1 |
| Organism: | Caenorhabditis elegans |
| Length: | 462 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hsd-1.
| Description | E-value | Query Range |
Subject Range |
|
|
300.0 | [0..45] | [431..3] |
|
Region A: Residues: [1-462] |
1 11 21 31 41 51
| | | | | |
1 MSIKRLSMRL KKGIHRSWNR MTSLEAGLEE EKEIKIVEEP EPRPWKVLIT GGAGHLAENL 60
61 VAKLEEMTRD SIRPKIREML EKEMPAVIST KVDKEVEKRL PMYIQIVLVD VLEPRGRVLK 120
121 HHVAFVKCSF DDECTMKTAL EQVDTVYHLA AVGMTGQYAR DRKACMDINA VGTMNLLIWA 180
181 RNSGVQRFIY TSSVGVVFSG EPMYNATEEV GYPDDFYNYY CESKAHAERI VQKASGHRMR 240
241 TTVLRFNGIY GPGEKRVTER VVKFMLTGMW IATCKPNGVE AQTQLSSVAN CIQGLVKAEL 300
301 ALRWSDTPHG QIYNIMDKTP VGTFSFWTPL NIALGFSSSM ITVPATPIRL FAYLSQIIAD 360
361 RMRIDPIVSV LEVDLLLVNN TFNIEKAERD LGYEPSVSAI PEIIEHYLHR LPPDVVRPKG 420
421 RSDFYVKVAV LVLGTILIFV AVFSFTFWMY LIFQRLSRWN PF
|
| Detection Method: |  |
| Confidence: | 62.39794 |
| Match: | 1z45A |
| Description: | Crystal structure of the gal10 fusion protein galactose mutarotase/UDP-galactose 4-epimerase from Saccharomyces cerevisiae complexed with NAD, UDP-glucose, and galactose |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| steroid dehydrogenase activity | 3.70115036051018 | bayes_pls_golite062009 |
| steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 3.56748749904419 | bayes_pls_golite062009 |
| retinol dehydrogenase activity | 3.08644105481774 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on CH-OH group of donors | 2.27417613545298 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 1.97774592602866 | bayes_pls_golite062009 |
| 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity | 1.80383455383329 | bayes_pls_golite062009 |
| catalytic activity | 1.79741889688267 | bayes_pls_golite062009 |
| ethanol binding | 1.43137718523288 | bayes_pls_golite062009 |
| retinol binding | 1.36627553306209 | bayes_pls_golite062009 |
| C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity | 1.03845584151228 | bayes_pls_golite062009 |
| DNA binding | 0.925435782369235 | bayes_pls_golite062009 |
| receptor activity | 0.870552554168634 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.848495583450678 | bayes_pls_golite062009 |
| transcription regulator activity | 0.830735196151903 | bayes_pls_golite062009 |
| nucleic acid binding | 0.805690663404413 | bayes_pls_golite062009 |
| benzaldehyde dehydrogenase activity | 0.74738022559788 | bayes_pls_golite062009 |
| retinoid binding | 0.67821643688355 | bayes_pls_golite062009 |
| alcohol dehydrogenase (NAD) activity | 0.65743456407889 | bayes_pls_golite062009 |
| signal transducer activity | 0.620476349006324 | bayes_pls_golite062009 |
| molecular transducer activity | 0.620476349006324 | bayes_pls_golite062009 |
| 11-beta-hydroxysteroid dehydrogenase activity | 0.617411823427239 | bayes_pls_golite062009 |
| isoprenoid binding | 0.56322670082984 | bayes_pls_golite062009 |
| binding | 0.553666136934364 | bayes_pls_golite062009 |
| testosterone 17-beta-dehydrogenase activity | 0.532187027260366 | bayes_pls_golite062009 |
| coenzyme binding | 0.46570602169425 | bayes_pls_golite062009 |
| NAD or NADH binding | 0.44922383360529 | bayes_pls_golite062009 |
| oxidoreductase activity | 0.39101464838432 | bayes_pls_golite062009 |
| transcription factor activity | 0.288669328257774 | bayes_pls_golite062009 |
| all-trans retinal binding | 0.218888750914841 | bayes_pls_golite062009 |
| NADPH:quinone reductase activity | 0.0435917990586205 | bayes_pls_golite062009 |
