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Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. Catalysis of the reaction: 3-beta-hydroxy-4-beta-methyl-5-alpha-cholesta-8,24-dien-4-alpha-carboxylate + NAD(P)+ = 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-one + CO2 + NAD(P)H. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
Acc: GO:0000252
Aspect: Molecular Function
Desc: Catalysis of the reaction: 3-beta-hydroxy-4-beta-methyl-5-alpha-cholesta-8,24-dien-4-alpha-carboxylate + NAD(P)+ = 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-one + CO2 + NAD(P)H.
Synonyms:
  • sterol 4alpha-carboxylic decarboxylase activity
  • 3beta-hydroxy-4beta-methylcholestenoate dehydrogenase activity
  • 3beta-hydroxy-4beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)
  • 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate:NAD(P)+ 3-oxidoreductase (decarboxylating)
  • C-3 sterol dehydrogenase (C-4 decarboxylase) activity
  • C-3 sterol dehydrogenase activity
  • sterol-4-carboxylate 3-dehydrogenase (decarboxylating) activity
  • sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
  • 3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)
Proteins in PDR annotated with:
   This term: 4 [Search]
   Term or descendants: 4 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0000252 - C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity (interactive image map)

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