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Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative. Catalysis of the reaction: NAD+ + testosterone = NADH + H+ + androst-4-ene-3,17-dione. Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity
Acc: GO:0047035
Aspect: Molecular Function
Desc: Catalysis of the reaction: NAD+ + testosterone = NADH + H+ + androst-4-ene-3,17-dione.
Synonyms:
  • 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
  • 3alpha,17beta-hydroxy steroid dehydrogenase activity
  • 3alpha(or 17beta)-hydroxysteroid:NAD+ oxidoreductase activity
  • 3alpha(17beta)-HSD
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 3 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0047035 - 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity (interactive image map)
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