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Protein Overview: SPBC1685.08

General Information:
Name(s) found: SPBC1685.08 [Sanger Pombe]
Description(s) found:
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  • pir||T39524 hypothetical protein SPBC1685.08 - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|3367791|emb|CAA20056.1| histone deacetylase complex subunit Cti6 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112004|ref|NP_595212.1| histone deacetylase complex subunit Cti6 [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • gi|121773118|sp|Q1MTR4.1|CTI6_SCHPO RecName: Full=Putative histone deacetylase complex subunit cti6 [NCBI NR]
  • histone deacetylase complex subunit Cti6 [Sanger Pombe]
  • Putative histone deacetylase complex subunit cti6 OS=Schizosaccharomyces pombe GN=cti6 PE=1 SV=1 [Swiss-Prot]
  • ZINC FINGER PROTEIN; ZF-PHD FINGER (2); SIMILAR TO S. CEREVISIAE YPL181W; GFP FUSION LOCALIZES TO NUCLEUS AND CYTOPLASM: O74328;Q9USG2; [pompepVF.fasta]
  • HYPOTHETICAL PROTEIN; SIMILAR TO S. CEREVISIAE YPL181W; CONTAINS PHD-FINGER DOMAIN; GFP FUSION LOCALISES TO NUCLEUS AND CYTOPLASM: O74328;Q9USG2; [pompepV13]
  • Hypothetical 47.0 kDa protein C1685.08 in chromosome II [pompep4896]
  • |||putative transcriptional regulator [pompepnew.fasta]
  • |||zinc finger protein|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • hypothetical protein [Schizosaccharomyces pombe]gi|3367791|emb|CAA20056.1| zinc finger protein; zf-PHD finger; non-essential (PMID 12618370); similar to S. cerevisiae YPL181W; localization nucleus (GFP); localization cytoplasm (GFP); interacts with SPBC2 [nrdb_11152004_Chlamydomonas]
  • (O74328) Hypothetical 47.0 kDa protein C1685.08 in chromosome II [pompep4896_normal_reversed]
  • |cti6||histone deacetylase complex subunit Cti6|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPBC1685.08 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPBC1685.08 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Putative histone deacetylase complex subunit cti6 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=cti6 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 424 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    Rpd3L-Expanded complex [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Rpd3S complex [IDALink to PubMed article]
    Biological Process: chromatin remodeling [NAS]
    regulation of transcription, DNA-dependent [ISSLink to PubMed article]
    histone deacetylation [ISSLink to PubMed article]
    gene-specific transcription from RNA polymerase II promoter [NAS]
    Molecular Function: zinc ion binding [IEA]
    transcription factor binding [ISSLink to PubMed article]
    small conjugating protein ligase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSNSTPANE EKEEESEKIQ KSPVDTPHTP NGSVSDNEEN ETSSTGEVTR CVCGIVESDD  60
   61 EASDGGLYIQ CDQCSVWQHG NCVGFADESE VPEVYYCEIC HPEFHKVYQR GRGAKQSKYL 120
  121 GNGKPIEASQ TEESSSTPPS PATKKSSKQR LTMNSRDAAL DYEEYLAIAK EKSLIPRRSR 180
  181 GRTSSKSLSP PAPQDESQGT EINLKQKIEE ENDEILEDSK ESKDENEENK ETSTTNVAET 240
  241 DAPEEETVDT VEEIADEEKH SVKEESGEAS PQSSQQSTIT SISTTTRSTR KAKREAAAED 300
  301 KADLPAAVAP KPSKTRKVGG RRGKSSSNDN HRIPQLHPDG TFVETITKPK GLHSRITMTE 360
  361 MRRRVASMLE YIGHIQVEMA AQSAGNQSST KSSKEGPEEE KETLRMVDNL TRDLLHWEQR 420
  421 FSRT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..107] PSI-BLAST 8.69897 Solution structure of PHD domain in death inducer-obliterator 1(DIO-1)
    2 View Details [108..209] deduced N/A No confident structure predictions are available.
    3 View Details [210..424] MSA 1.172996 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein deacetylase activity
    		•  7.50578521120904 bayes_pls_golite062009
  • histone deacetylase activity
    		•  7.35162059871663 bayes_pls_golite062009
  • deacetylase activity
    		•  6.55925777139018 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
    		•  5.24378850198774 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  4.39452339322141 bayes_pls_golite062009
  • methylated histone residue binding
    		•  4.19057851212315 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  3.20023500652896 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  3.20023500652896 bayes_pls_golite062009
  • histone binding
    		•  3.01402804224903 bayes_pls_golite062009
  • binding
    		•  2.93415748500038 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.89424169822343 bayes_pls_golite062009
  • DNA binding
    		•  2.67786232715949 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.6327300364647 bayes_pls_golite062009
  • nucleosome binding
    		•  1.69494047037058 bayes_pls_golite062009
  • transcription factor activity
    		•  1.62385700361588 bayes_pls_golite062009
  • protein binding
    		•  1.42349040268084 bayes_pls_golite062009
    		• 1.38236406424542 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  1.19037129579681 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  0.873079221910902 bayes_pls_golite062009
  • transcription activator activity
    		•  0.739132967687069 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.507152521861549 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  0.476506467104495 bayes_pls_golite062009
  • protein kinase activity
    		•  0.405766438875014 bayes_pls_golite062009
  • acetyltransferase activity
    		•  0.39905022319963 bayes_pls_golite062009
  • chromatin binding
    		•  0.39425178848458 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.327424740985033 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.199823005659601 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.14235705491362 bayes_pls_golite062009
  • kinase activity
    		•  0.12732151557306 bayes_pls_golite062009
    		• 0.0927457062201698 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.0725773086825168 bayes_pls_golite062009
  • transcription factor binding
    		•  0.0538806851320555 bayes_pls_golite062009
  • histone methyltransferase activity (H3-K4 specific)
    		•  0.0490968711985191 bayes_pls_golite062009
  • histone acetyl-lysine binding
    		•  0.0410393640547611 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle