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Protein Overview: pst3

General Information:
Name(s) found: pst3 / SPBC1734.16c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • SIN3 family co-repressor [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1154 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    nuclear chromatin [ICLink to PubMed article]
    Rpd3L-Expanded complex [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Rpd3S complex [IDALink to PubMed article]
    Biological Process: chromatin remodeling [NAS]
    regulation of transcription, DNA-dependent [ICLink to PubMed article]
    chromatin silencing [ISSLink to PubMed article]
    histone deacetylation [ICLink to PubMed article]
    double-strand break repair via nonhomologous end joining [ISS]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDVMNVPVDS ERDNPGDKVE TQSDKNHLPK ASPSQSQSPV NTSLHNGDGK DNGVATEPVE  60
   61 NKQILSERSV TRDDYEKGKT IVSSLALSSI SGKDGSISSQ NAEGLSSSSN RPLDVNDALS 120
  121 YLELVKYYFS ERREIYNRFL EIMRDFKSQA LDTLGVINRV SELFNGYPQL IEGFNTFLPS 180
  181 GYKIEVQLDS SNTSVVRVGT PMHPLPQQGV QSTLPVAPSN EDQRTMESTS PTDSQPQPSA 240
  241 PNLVSSTENE KPRVDFNYAI AYMNKVKARY PPNSDTYMEF LGVLRTYQKA QKSIFEVRAR 300
  301 VAEIFKDSPD LLEEFKLFLP DNVDSTEPST PNVQKSPNRL PPVGNFSLPP SAPVREKRNR 360
  361 PAHSAQISRS ISKTSRMYRQ TAEEPLNSYS LHVYPQKITA PTSPYAATQE ELLAFTTIRQ 420
  421 HLPDTLAFHK FLELLHLYRE KLLDKTELLN SFSKLVRNDN LTLWFSEFIR WSDNPILVKN 480
  481 EPVDERVYLP ETFECISLTY RKLPDSWKQD KCSGRDDLDN SVLNDDYISV APKPSHVKNI 540
  541 MHHENQYLQA LQLVEDERYD YDRVLNTTES AIKILANFCE PTIHEHLETA LQELERSKRI 600
  601 IKNALIIVYG KEHANLALDT LFKKLPTAAP VLLKRIKTKD QEWRRSKREW SKIWRQIEKK 660
  661 NAQAAFDDRY CRIEGRDRRG LSYSRILRDI DDIYQRQKHR IDGAKLGFQF TQVLCDSLIF 720
  721 LNILRLSDAQ LTNSSFYSYA DKGRISAVLK ALLSQFFGIP LPREALETNL ASENIESVKK 780
  781 HRDGLSKIFI RPESADNSNN TNVSFQTDET QTEDETMSDI HPDDVENHSK SKFLGEESKN 840
  841 IIGYNFFGNA TMYVLFRLIC VCYSRLEHIK LFVESSTIYA SSTGGYENIL NICEKYLKGS 900
  901 CSRLEFRKYL QKFNNETCYM ICSIERLLKV IFYRIHEILL DPKLGQLLLL FESDGANSVT 960
  961 TPREQMVYRN HVESILAPES KIFNMRWYPL EKRLCIQQLL PADLTMHDFE NPAKAFMYYV1020
 1021 DSYAISHITE GVDLMQVKMP FLRRSLQRIS QQGYLAGRGS GRLHSLFNEH FCKSNLQLFF1080
 1081 STDTYVIFFE PNTENVYINS YNLWVDQSSQ SKKQNRTTNW RRWLESDEGW RKSKANTDIK1140
 1141 FFSETTLDQC IEAM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..102] MSA 106.155997 View MSA. No confident structure predictions are available.
    2 View Details [103..209] PSI-BLAST 30.0 Solution structure of the NRSF/REST-mSin3B PAH1 complex
    3 View Details [210..377] PSI-BLAST 22.221849 No description for 2f05A was found.
    4 View Details [378..529] FFAS03 2.5 No description for 2f05A was found.
    5 View Details [530..760] MSA 1.076967 View MSA. No confident structure predictions are available.
    6 View Details [761..829] deduced N/A No confident structure predictions are available.
    7 View Details [830..1003] MSA 1.051981 View MSA. No confident structure predictions are available.
    8 View Details [1004..1154] MSA 1.044979 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • protein deacetylase activity
    		•  9.15317765173842 bayes_pls_golite062009
  • histone deacetylase activity
    		•  9.00540919224423 bayes_pls_golite062009
  • deacetylase activity
    		•  7.91874136549804 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
    		•  6.08470985892139 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  4.91057345050982 bayes_pls_golite062009
  • transcription repressor activity
    		•  4.58162229232685 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.97924147512738 bayes_pls_golite062009
  • transcription corepressor activity
    		•  3.71696410617503 bayes_pls_golite062009
  • transcription factor binding
    		•  3.06004981994503 bayes_pls_golite062009
  • transcription cofactor activity
    		•  2.96293930027313 bayes_pls_golite062009
  • DNA binding
    		•  2.90699688513784 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.89854237920034 bayes_pls_golite062009
  • binding
    		•  2.65480555250736 bayes_pls_golite062009
  • transcription factor activity
    		•  2.07660852403223 bayes_pls_golite062009
  • protein binding
    		•  1.46569798429756 bayes_pls_golite062009
  • transcription coactivator activity
    		•  1.06494495723884 bayes_pls_golite062009
  • transcription activator activity
    		•  0.63586266373929 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.599183685811182 bayes_pls_golite062009
  • catalytic activity
    		•  0.289349813503192 bayes_pls_golite062009
    4
    Term Confidence Notes
  • protein deacetylase activity
    		•  8.92489148049718 bayes_pls_golite062009
  • histone deacetylase activity
    		•  8.77562367748348 bayes_pls_golite062009
  • deacetylase activity
    		•  7.74805102638387 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
    		•  5.99241841178307 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  4.85992273034906 bayes_pls_golite062009
  • transcription repressor activity
    		•  4.25514230798992 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.82193713323077 bayes_pls_golite062009
  • transcription corepressor activity
    		•  3.30769773581294 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.83214064778422 bayes_pls_golite062009
  • DNA binding
    		•  2.82083682611814 bayes_pls_golite062009
  • transcription factor binding
    		•  2.73494763175272 bayes_pls_golite062009
  • transcription cofactor activity
    		•  2.59356984380124 bayes_pls_golite062009
  • binding
    		•  2.59005615358803 bayes_pls_golite062009
  • transcription factor activity
    		•  1.99794029160509 bayes_pls_golite062009
  • protein binding
    		•  1.36724461365736 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.918453145717461 bayes_pls_golite062009
  • transcription activator activity
    		•  0.570282420961288 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.512364998565023 bayes_pls_golite062009
  • catalytic activity
    		•  0.30211814650972 bayes_pls_golite062009
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle