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Protein Overview: psm3

General Information:
Name(s) found: psm3 / SPAC10F6.09c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • mitotic cohesin complex subunit Psm3 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1194 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    nuclear chromatin [ICLink to PubMed article]
    cytosol [IDALink to PubMed article]
    mitotic cohesin complex [TASLink to PubMed article]
    condensed nuclear chromosome [ICLink to PubMed article]
    Biological Process: mitotic sister chromatid cohesion [IMPLink to PubMed article]
    protein ubiquitination [ISSLink to PubMed article]
    Molecular Function: ATPase activity [ISSLink to PubMed article]
    ATP binding [IEA]
    protein binding [IPILink to PubMed article]
    protein heterodimerization activity [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYITKIVIQG FKSYKDYTVI EPLSPHHNVI VGRNGSGKSN FFAAIRFVLS DAYTHLSREE  60
   61 RQALLHEGPG ATVMSAYVEV TFANADNRFP TGKSEVVLRR TIGLKKDEYS LDKKTVSKTE 120
  121 VINLLESAGF SRSNPYYIVP QGRVTSLTNA KDSERLELLK EVAGTQIYEN RRAESNKIMD 180
  181 ETIQKSEKID ELLQYIEERL RELEEEKNDL AVYHKKDNER RCLEYAIYSR EHDEINSVLD 240
  241 ALEQDRIAAL ERNDDDSGAF IQREERIERI KAEITELNHS LELLRVEKQQ NDEDYTNIMK 300
  301 SKVALELQSS QLSRQIEFSK KDESSKLNIL SELESKISEK ENELSEILPK YNAIVSEADD 360
  361 LNKRIMLLKN QKQSLLDKQS RTSQFTTKKE RDEWIRNQLL QINRNINSTK ENSDYLKTEY 420
  421 DEMENELKAK LSRKKEIEIS LESQGDRMSQ LLANITSINE RKENLTDKRK SLWREEAKLK 480
  481 SSIENVKDDL SRSEKALGTT MDRNTSNGIR AVKDIAERLK LEGYYGPLCE LFKVDNRFKV 540
  541 AVEATAGNSL FHIVVDNDET ATQILDVIYK ENAGRVTFMP LNKLRPKAVT YPDASDALPL 600
  601 IQYLEFDPKF DAAIKQVFSK TIVCPSIETA SQYARSHQLN GITLSGDRSD KKGALTAGYR 660
  661 DYRNSRLDAI KNVKTYQIKF SDLQESLEKC RSEIESFDQK ITACLDDLQK AQLSLKQFER 720
  721 DHIPLKDELV TITGETTDLQ ESMHHKSRML ELVVLELHTL EQQANDLKSE LSSEMDELDP 780
  781 KDVEALKSLS GQIENLSHEF DAIIKERAHI EARKTALEYE LNTNLYLRRN PLKAEIGSDN 840
  841 RIDESELNSV KRSLLKYENK LQIIKSSSSG LEEQMQRINS EISDKRNELE SLEELQHEVA 900
  901 TRIEQDAKIN ERNAAKRSLL LARKKECNEK IKSLGVLPEE AFIKYVSTSS NAIVKKLHKI 960
  961 NEALKDYGSV NKKAYEQFNN FTKQRDSLLA RREELRRSQE SISELTTVLD QRKDEAIERT1020
 1021 FKQVAKSFSE IFVKLVPAGR GELVMNRRSE LSQSIEQDIS MDIDTPSQKS SIDNYTGISI1080
 1081 RVSFNSKDDE QLNINQLSGG QKSLCALTLI FAIQRCDPAP FNILDECDAN LDAQYRSAIA1140
 1141 AMVKEMSKTS QFICTTFRPE MVKVADNFYG VMFNHKVSTV ESISKEEAMA FVEG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..186] PSI-BLAST 37.154902 Structural biochemistry of ATP-driven dimerization and DNA stimulated activation of SMC ATPases.
    2 View Details [187..499] FFAS03 2.9 Tropomyosin
    3 View Details [500..649] FFAS03 5.13 Smc hinge domain
    4 View Details [650..1037] FFAS03 2.07 The modeled structure of fibritin (gpwac) of bacteriophage T4 based on cryo-EM reconstruction of the extended tail of bacteriophage T4
    5 View Details [1038..1194] PSI-BLAST 18.522879 Structural biochemistry of ATP-driven dimerization and DNA stimulated activation of SMC ATPases.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • microtubule motor activity
    		•  4.51968578934603 bayes_pls_golite062009
  • motor activity
    		•  4.04927796049806 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  2.72462789867829 bayes_pls_golite062009
  • tubulin binding
    		•  2.67743463093593 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • microtubule binding
    		•  2.59155206524122 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.4101693596493 bayes_pls_golite062009
  • DNA helicase activity
    		•  2.2817164193758 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.16381244011837 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.13284212711072 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.11265775498161 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.11046854230259 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  1.88455339138556 bayes_pls_golite062009
  • actin binding
    		•  1.75397031486306 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.71108735370276 bayes_pls_golite062009
  • helicase activity
    		•  1.70242731830224 bayes_pls_golite062009
  • hydrolase activity
    		•  1.66122526893602 bayes_pls_golite062009
  • ATPase activity
    		•  1.53315090215319 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  1.48507469226102 bayes_pls_golite062009
  • plus-end-directed microtubule motor activity
    		•  1.38366133153678 bayes_pls_golite062009
  • protein-DNA loading ATPase activity
    		•  1.29640539057136 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.2935968641033 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.2935353851804 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.29138695385133 bayes_pls_golite062009
  • nucleotide binding
    		•  1.28669586915546 bayes_pls_golite062009
  • microfilament motor activity
    		•  1.20923670094205 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  1.14622346285179 bayes_pls_golite062009
  • DNA clamp loader activity
    		•  1.12431517057397 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.08697924060619 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • ATP binding
    		•  0.98146619596929 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.949788783884952 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.931486373329219 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.899234598488971 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.782430219754236 bayes_pls_golite062009
  • actin filament binding
    		•  0.728264616959762 bayes_pls_golite062009
  • DNA binding
    		•  0.702147676354075 bayes_pls_golite062009
  • kinase activity
    		•  0.691112783105676 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.6071273686445 bayes_pls_golite062009
  • bubble DNA binding
    		•  0.572969182910824 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.499834566483656 bayes_pls_golite062009
  • recombinase activity
    		•  0.45851158693664 bayes_pls_golite062009
  • RNA helicase activity
    		•  0.34746349346164 bayes_pls_golite062009
  • centromeric DNA binding
    		•  0.322818640526369 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.312171320541728 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  0.30832907234141 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  0.29532978396745 bayes_pls_golite062009
  • four-way junction helicase activity
    		•  0.26252931460003 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.208665086324262 bayes_pls_golite062009
  • exodeoxyribonuclease V activity
    		•  0.185603938981231 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • 3'-5' DNA helicase activity
    		•  0.0769112340058804 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.0430764033739892 bayes_pls_golite062009
  • protein kinase activity
    		•  0.0364322017534667 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.0111338193708552 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.91859588671053 bayes_pls_golite062009
  • protein heterodimerization activity
    		•  1.04211475755928 bayes_pls_golite062009
  • protein binding
    		•  1.02696508439754 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.832846345187777 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.76561882762468 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.734314999998814 bayes_pls_golite062009
  • DNA binding
    		•  0.693468729072494 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.489361130553895 bayes_pls_golite062009
  • DNA secondary structure binding
    		•  0.370893450957454 bayes_pls_golite062009
  • catalytic activity
    		•  0.265320175609019 bayes_pls_golite062009
  • ATP binding
    		•  0.161090462621035 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.132019153736693 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.123699115804833 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.00495036379814584 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle