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Protein Overview: rad17

General Information:
Name(s) found: rad17 / SPAC14C4.13 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • RFC related checkpoint protein Rad17 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 606 amino acids

    Gene Ontology:
    Cellular Component: nuclear chromatin [ICLink to PubMed article]
    Rad17 RFC-like complex [TASLink to PubMed article]
    Biological Process: DNA damage checkpoint [IMPLink to PubMed article]
    DNA repair [IEA]
    DNA replication checkpoint [IMPLink to PubMed article]
    intra-S DNA damage checkpoint [IMPLink to PubMed article]
    Molecular Function: ATP binding [ISSLink to PubMed article]
    DNA clamp loader activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRQLSFHES TKRSLKKKKI RKIEKPSLVS KTSRDKNASI TDIHEEDIEA FSDEENKIVH  60
   61 LNNLKEDRFQ LWFEKYIPQK AADLAVHKSK ISAIKQWMLT DSLESRLLLI CGPSGCGKST 120
  121 AVQVLAKELG YSLIEWLNPM NLKEPSNQES DTLSLTEKFS RFMSLCETYP ELELMDSNNI 180
  181 QKRGKNAQGK KKFIFLDEIP HLSKFNGSLD AFRNVIRTAL TSRGAFSIIM VLTEIQLNNL 240
  241 EGINSQDRNS FNSVQIMGND LLQDPRVTVL QFNPIAPTYM KKCLGSILRK EGVPKSPKLL 300
  301 SLVENICSAS EGDLRSAINS LQLSISQSFE KKGTKNIREV KEGKGKGNDF SLEAAQVLER 360
  361 LSKSDSEAYA RFKNYKSAYI PKSDKNENSF FKKDVGLGMM HAIGKVVWNK REGDDEVLKA 420
  421 SSQQTGNSER IKGVKVSKSQ ENKNCISLKS DQRERMLNVD QCFTSKRRSL VDIESTINQS 480
  481 GLSGSVFRYG LFENYVDSCV TTDEAFNVCD LLSISDCLSH DFPYSYTGDE ISTWFSVQGT 540
  541 LFYLPSPVPR KWRQLRFQQW NNEGIVRGIF DDYMVIYGKR SVSDPVIEAH EDQVLEDIDD 600
  601 PIEDED

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..606] PSI-BLAST 55.522879 N-terminal, ClpS-binding domain of ClpA, an Hsp100 chaperone; ClpA, an Hsp100 chaperone, AAA+ modules

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • DNA clamp loader activity
    		•  7.24220238701961 bayes_pls_golite062009
  • protein-DNA loading ATPase activity
    		•  7.13475422349101 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  2.72462789867829 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • DNA helicase activity
    		•  2.2817164193758 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.21184938313192 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.13284212711072 bayes_pls_golite062009
  • DNA binding
    		•  1.94055378599526 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  1.88455339138556 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.83584389083042 bayes_pls_golite062009
  • helicase activity
    		•  1.70242731830224 bayes_pls_golite062009
  • DNA replication origin binding
    		•  1.62491387774159 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.2539059700735 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.21658213854831 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.21652144153182 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.21571071905795 bayes_pls_golite062009
  • nucleotide binding
    		•  1.20347573865566 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  1.117585097627 bayes_pls_golite062009
  • motor activity
    		•  1.03253378953548 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  0.971476020912368 bayes_pls_golite062009
  • DNA polymerase activity
    		•  0.928091843881235 bayes_pls_golite062009
  • microtubule motor activity
    		•  0.83915812897953 bayes_pls_golite062009
  • transcription factor activity
    		•  0.697256579145077 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.677612020025357 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.469700751396708 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  0.388587892299301 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  0.372638007722845 bayes_pls_golite062009
  • GTP binding
    		•  0.364508542344128 bayes_pls_golite062009
  • mismatched DNA binding
    		•  0.19287888096404 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.147579541298736 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.113504049290503 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.111293884322157 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.089234257580272 bayes_pls_golite062009
  • 3'-5' DNA helicase activity
    		•  0.0769112340058804 bayes_pls_golite062009
  • GTPase activity
    		•  0.0742799394423282 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle