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View Structure Prediction Details

Protein: rad17
Organism: Schizosaccharomyces pombe
Length: 606 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rad17.

Description E-value Query
Range
Subject
Range
gi|1586087 - gi|1586087|prf||2203263A rad17 gene
299.0 [0..1] [595..1]
gi|74317255, gi|... - gi|74317255|ref|YP_314995.1| ATP-dependent Clp protease ATP-binding subunit ClpA [Thiobacillus denit...
249.0 [0..36] [605..143]
gi|34499124, gi|... - gi|34499124|ref|NP_903339.1| ATP-dependent Clp protease, ATP-binding subunit [Chromobacterium violac...
247.0 [0..66] [605..175]
gi|71848329, gi|... - gi|71908708|ref|YP_286295.1| AAA ATPase, central region:Clp, N terminal [Dechloromonas aromatica RCB...
245.0 [0..80] [605..183]
gi|46580013, gi|... - gi|46580013|ref|YP_010821.1| ATP-dependent Clp protease, ATP-binding subunit ClpA [Desulfovibrio vul...
gi|241881283, gi... - gi|241906690|ref|ZP_04791272.1| ATP-dependent Clp protease, ATP-binding subunit clpA [Desulfovibrio ...
245.0 [0..72] [605..173]
gi|76809374, gi|... - gi|76809374|ref|YP_332525.1| ATP-dependent Clp protease ATP-binding subunit clpA [Burkholderia pseud...
245.0 [0..69] [605..294]
gi|120602576, gi... - gi|120602576|ref|YP_966976.1| ATP-dependent Clp protease, ATP-binding subunit clpA [Desulfovibrio vu...
245.0 [0..72] [605..173]
gi|47574776 - gi|47574776|ref|ZP_00244811.1| COG0542: ATPases with chaperone activity, ATP-binding subunit [Rubriv...
245.0 [0..69] [605..179]
gi|77459812, gi|... - gi|77459812|ref|YP_349319.1| ATP-dependent Clp protease ATP-binding subunit ClpA [Pseudomonas fluore...
244.0 [0..72] [605..180]
gi|116058774 - gi|116058774|emb|CAL54481.1| AAA ATPase, central region:Clp, N terminal:C (ISS) [Ostreococcus tauri]
243.0 [0..36] [601..176]

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Predicted Domain #1
Region A:
Residues: [1-606]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRQLSFHES TKRSLKKKKI RKIEKPSLVS KTSRDKNASI TDIHEEDIEA FSDEENKIVH  60
   61 LNNLKEDRFQ LWFEKYIPQK AADLAVHKSK ISAIKQWMLT DSLESRLLLI CGPSGCGKST 120
  121 AVQVLAKELG YSLIEWLNPM NLKEPSNQES DTLSLTEKFS RFMSLCETYP ELELMDSNNI 180
  181 QKRGKNAQGK KKFIFLDEIP HLSKFNGSLD AFRNVIRTAL TSRGAFSIIM VLTEIQLNNL 240
  241 EGINSQDRNS FNSVQIMGND LLQDPRVTVL QFNPIAPTYM KKCLGSILRK EGVPKSPKLL 300
  301 SLVENICSAS EGDLRSAINS LQLSISQSFE KKGTKNIREV KEGKGKGNDF SLEAAQVLER 360
  361 LSKSDSEAYA RFKNYKSAYI PKSDKNENSF FKKDVGLGMM HAIGKVVWNK REGDDEVLKA 420
  421 SSQQTGNSER IKGVKVSKSQ ENKNCISLKS DQRERMLNVD QCFTSKRRSL VDIESTINQS 480
  481 GLSGSVFRYG LFENYVDSCV TTDEAFNVCD LLSISDCLSH DFPYSYTGDE ISTWFSVQGT 540
  541 LFYLPSPVPR KWRQLRFQQW NNEGIVRGIF DDYMVIYGKR SVSDPVIEAH EDQVLEDIDD 600
  601 PIEDED

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.522879
Match: 1ksfX
Description: N-terminal, ClpS-binding domain of ClpA, an Hsp100 chaperone; ClpA, an Hsp100 chaperone, AAA+ modules
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA clamp loader activity 7.24220238701961 bayes_pls_golite062009
protein-DNA loading ATPase activity 7.13475422349101 bayes_pls_golite062009
DNA-dependent ATPase activity 2.72462789867829 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
DNA helicase activity 2.2817164193758 bayes_pls_golite062009
nucleic acid binding 2.21184938313192 bayes_pls_golite062009
pyrophosphatase activity 2.13284212711072 bayes_pls_golite062009
DNA binding 1.94055378599526 bayes_pls_golite062009
ATP-dependent DNA helicase activity 1.88455339138556 bayes_pls_golite062009
transcription regulator activity 1.83584389083042 bayes_pls_golite062009
helicase activity 1.70242731830224 bayes_pls_golite062009
DNA replication origin binding 1.62491387774159 bayes_pls_golite062009
structure-specific DNA binding 1.2539059700735 bayes_pls_golite062009
purine ribonucleotide binding 1.21658213854831 bayes_pls_golite062009
ribonucleotide binding 1.21652144153182 bayes_pls_golite062009
purine nucleotide binding 1.21571071905795 bayes_pls_golite062009
nucleotide binding 1.20347573865566 bayes_pls_golite062009
purine NTP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
ATP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
double-stranded DNA binding 1.117585097627 bayes_pls_golite062009
motor activity 1.03253378953548 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
DNA-directed DNA polymerase activity 0.971476020912368 bayes_pls_golite062009
DNA polymerase activity 0.928091843881235 bayes_pls_golite062009
microtubule motor activity 0.83915812897953 bayes_pls_golite062009
transcription factor activity 0.697256579145077 bayes_pls_golite062009
transcription repressor activity 0.677612020025357 bayes_pls_golite062009
single-stranded DNA binding 0.469700751396708 bayes_pls_golite062009
guanyl nucleotide binding 0.388587892299301 bayes_pls_golite062009
guanyl ribonucleotide binding 0.372638007722845 bayes_pls_golite062009
GTP binding 0.364508542344128 bayes_pls_golite062009
mismatched DNA binding 0.19287888096404 bayes_pls_golite062009
protein binding 0.170837278876362 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.147579541298736 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.113504049290503 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.111293884322157 bayes_pls_golite062009
structural constituent of ribosome 0.089234257580272 bayes_pls_golite062009
3'-5' DNA helicase activity 0.0769112340058804 bayes_pls_golite062009
GTPase activity 0.0742799394423282 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle