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Protein Overview: cut7

General Information:
Name(s) found: cut7 / SPAC25G10.07c [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • kinesin-like protein Cut7 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1085 amino acids

    Gene Ontology:
    Cellular Component: spindle microtubule [IDALink to PubMed article]
    nucleus [IDALink to PubMed article]
    microtubule cytoskeleton [IDALink to PubMed article]
    spindle pole body [IDALink to PubMed articleLink to PubMed article]
    microtubule associated complex [ICLink to PubMed article]
    Biological Process: spindle organization [IMPLink to PubMed article]
    mitotic sister chromatid segregation [ISSLink to PubMed article]
    microtubule-based movement [ISSLink to PubMed article]
    Molecular Function: ATP binding [IEA]
    microtubule motor activity [ISSLink to PubMed article]
    protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPRVAPGGS QQFLGKQGLK AKNPVSTPNS HFRSASNPRK RREPPTIDTG YPDRSDTNSP  60
   61 TDHALHDENE TNINVVVRVR GRTDQEVRDN SSLAVSTSGA MGAELAIQSD PSSMLVTKTY 120
  121 AFDKVFGPEA DQLMLFENSV APMLEQVLNG YNCTIFAYGQ TGTGKTYTMS GDLSDSDGIL 180
  181 SEGAGLIPRA LYQLFSSLDN SNQEYAVKCS YYELYNEEIR DLLVSEELRK PARVFEDTSR 240
  241 RGNVVITGIE ESYIKNAGDG LRLLREGSHR RQVAATKCND LSSRSHSIFT ITLHRKVSSG 300
  301 MTDETNSLTI NNNSDDLLRA SKLHMVDLAG SENIGRSGAE NKRARETGMI NQSLLTLGRV 360
  361 INALVEKAHH IPYRESKLTR LLQDSLGGKT KTSMIVTVSS TNTNLEETIS TLEYAARAKS 420
  421 IRNKPQNNQL VFRKVLIKDL VLDIERLKND LNATRKKNGV YLAESTYKEL MDRVQNKDLL 480
  481 CQEQARKLEV LDLNVKSSRE QLQYVSKSNQ EHKKEVEALQ LQLVNSSTEL ESVKSENEKL 540
  541 KNELVLEIEK RKKYETNEAK ITTVATDLSQ YYRESKEYIA SLYEKLDRTE RNNKENENNF 600
  601 WNLKFNLLTM LRSFHGSFTD ETNGYFTLLN DFNASMEELL NTHSNQLLIS MTKITEHFQS 660
  661 LDEALQSARS SCAVPNSSLD LIVSELKDSK NSLLDALEHS LQDISMSSQK LGNGISSELI 720
  721 ELQKDMKESY RQLVQELRSL YNLQHTHEES QKELMYGVRN DIDALVKTCT TSLNDADIIL 780
  781 SDYISDQKSK FESKQQDLIA NIGKIVSNFL QEQNESLYTK ADILHSHLND TNSNIRKANE 840
  841 IMNNRSEEFL RNAASQAEIV GANKERIQKT VENGSQLLDS KSKAIHSNSR SMYDHCLALA 900
  901 ESQKQGVNLE VQTLDRLLQK VKEHSEDNTK EKHQQLLDLL ESLVGNNDNL IDSIKTPHTE 960
  961 LQKITDHVLK GTTSLANHTN ELLGLGDESL CNLETTIEDT SLVKLETTGD TPSKRELPAT1020
 1021 PSWTRDSSLI KETTNLNLDS DKKFVRETYT SSNQTNEPDV YDKPSNSSRT SLLRSSRSAY1080
 1081 SKMKR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..429] PSI-BLAST 61.30103 Crystal structure of the motor protein KSP in complex with ADP and monastrol
    2 View Details [430..698] FFAS03 2.17 Tropomyosin
    3 View Details [699..1085] PSI-BLAST 11.154902 Heavy meromyosin subfragment

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • microtubule motor activity
    		•  7.68336791348661 bayes_pls_golite062009
  • plus-end-directed microtubule motor activity
    		•  4.97507344344589 bayes_pls_golite062009
  • microfilament motor activity
    		•  4.176620576177 bayes_pls_golite062009
  • motor activity
    		•  4.04927796049806 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.95079405147356 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.87427509025394 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.85499564954033 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.85178667290149 bayes_pls_golite062009
  • actin-dependent ATPase activity
    		•  2.77140616759165 bayes_pls_golite062009
  • microtubule plus-end binding
    		•  2.71138928021716 bayes_pls_golite062009
  • tubulin binding
    		•  2.67743463093593 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • microtubule binding
    		•  2.59155206524122 bayes_pls_golite062009
  • transporter activity
    		•  2.58140740499725 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.4101693596493 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.39695871109024 bayes_pls_golite062009
  • ATPase activity
    		•  2.39535714892224 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.18396165590908 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  2.07967285635739 bayes_pls_golite062009
  • actin binding
    		•  1.75397031486306 bayes_pls_golite062009
  • hydrolase activity
    		•  1.57549510726226 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.40384549325664 bayes_pls_golite062009
  • helicase activity
    		•  1.33212695797068 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.29730375126024 bayes_pls_golite062009
  • protein binding
    		•  1.22129154759482 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  1.07479235523606 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.929901285538132 bayes_pls_golite062009
  • nucleotide binding
    		•  0.922442819194247 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.920987930180051 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.920926158369519 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.906554174337376 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.777787753097919 bayes_pls_golite062009
  • actin filament binding
    		•  0.728264616959762 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.579644950922817 bayes_pls_golite062009
  • kinetochore binding
    		•  0.505370954958131 bayes_pls_golite062009
  • DNA binding
    		•  0.479412476059825 bayes_pls_golite062009
  • GTPase activity
    		•  0.437665353870877 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.434775387083003 bayes_pls_golite062009
  • ATP binding
    		•  0.41092997612902 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  0.399434758448606 bayes_pls_golite062009
  • GTP binding
    		•  0.398333597279278 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  0.39332178627529 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.385813421701492 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.377870145186619 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.355466224802969 bayes_pls_golite062009
  • RNA helicase activity
    		•  0.34746349346164 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  0.328186246219424 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  0.328186246219424 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.312171320541728 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  0.30832907234141 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  0.29532978396745 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.294474570607914 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.282352478532746 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.25143870859482 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.25143870859482 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.220608508617331 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.219533217661421 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.219157471322311 bayes_pls_golite062009
  • protein transporter activity
    		•  0.178442534411253 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.17029946873911 bayes_pls_golite062009
  • mismatched DNA binding
    		•  0.13866566261611 bayes_pls_golite062009
  • minus-end-directed microtubule motor activity
    		•  0.068779631341469 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0254369227200564 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.0111338193708552 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle