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Protein Overview: csn1

General Information:
Name(s) found: csn1 / SPBC215.03c [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • COP9/signalosome complex subunit Csn1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 422 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    signalosome [TASLink to PubMed article]
    Biological Process: regulation of meiotic cell cycle [IMPLink to PubMed article]
    protein catabolic process [IGILink to PubMed article]
    regulation of meiosis [IMPLink to PubMed article]
    regulation of protein deneddylation [IMPLink to PubMed article]
    regulation of DNA replication [IMPLink to PubMed article]
    response to DNA damage stimulus [IMPLink to PubMed article]
    regulation of ubiquitin-protein ligase activity [NASLink to PubMed article]
    regulation of proteasomal ubiquitin-dependent protein catabolic process [NAS]
    cullin deneddylation [NAS]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLNLLVNQE ELKRYLDEYG VWSKIFRALF VARNSKPLRS FCVHYAIKEL KEKTYNLELY  60
   61 QSLFEEFQDC FENEQLDVEW VESVTFHRKQ NLEQLRRELK AYKNNLIRES IRAAQLDLAS 120
  121 FFADVGQFDS ALRSYAKVRE YCTNAGQIAH LSLELMRISI WIGNYSHVLA FGSRAKSTVS 180
  181 AAMELTSPIY AYCGLANFCL GDYEEALAHF LKVETDTSDG IITKTDISVY ISLCALACWD 240
  241 HKRLIQELER NEEFNALSDL DPSLRRCLQA KCNRKYSLLL DTLQQNAQDY SLDMYLAPQL 300
  301 TNLFSLIRER SLLDYLIPYS ALPFSKIAVD FHIDENFIEK NLLEIIEAKK LNGKVDSLQK 360
  361 RVYIEPSSEP ENFEDIKNIA QTSLLYSKAL YLQTLAAMNT ENTDDEAPVI AQTNITAEDS 420
  421 QN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..88] MSA 6.315996 View MSA. No confident structure predictions are available.
    2 View Details [89..239] PSI-BLAST 6.522879 Designed protein cTPR3
    3 View Details [240..422] PSI-BLAST 11.69897 Solution structure of the PCI domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • transcription regulator activity
    		•  5.29569167054278 bayes_pls_golite062009
  • DNA binding
    		•  4.90756541371868 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.69183445184264 bayes_pls_golite062009
  • transcription factor activity
    		•  4.14166958134441 bayes_pls_golite062009
  • binding
    		•  3.52874320222492 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.48053910222825 bayes_pls_golite062009
  • hydrolase activity
    		•  2.30467124306022 bayes_pls_golite062009
  • transcription activator activity
    		•  2.29614125067822 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.19033875364989 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.48055533524841 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.33374581364046 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  1.27763700765562 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.12147035668008 bayes_pls_golite062009
  • transcription factor binding
    		•  0.83705247708153 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.754042916649094 bayes_pls_golite062009
  • protein binding
    		•  0.753698599635855 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.486434906547244 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.286130392009263 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.249771970501337 bayes_pls_golite062009
  • transferase activity
    		•  0.064832527337659 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle