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View Structure Prediction Details

Protein: csn1
Organism: Schizosaccharomyces pombe
Length: 422 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for csn1.

Description E-value Query
Range
Subject
Range
gi|5670324 - gi|5670324|gb|AAC50906.2| Gps1 [Homo sapiens]
297.0 [0..4] [422..49]
gi|55732991 - gi|55732991|emb|CAH93182.1| hypothetical protein [Pongo abelii]
gi|55732991|emb|... - hypothetical protein [Pongo pygmaeus]
297.0 [0..4] [422..41]
gi|67970136 - gi|67970136|dbj|BAE01412.1| unnamed protein product [Macaca fascicularis]
296.0 [0..4] [422..36]
tr|A0A0G2JW80|A0... - Isoform of P97834, COP9 signalosome complex subunit 1 OS=Rattus norvegicus GN=Gps1 PE=1 SV=1
gi|75517042 - gi|75517042|gb|AAI03783.1| G protein pathway suppressor 1 [Mus musculus]
294.0 [0..4] [422..36]
gi|76645477, gi|... - gi|76645477|ref|XP_603925.2| PREDICTED: similar to G protein pathway suppressor 1 isoform 1 [Bos tau...
292.0 [0..4] [422..20]

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Predicted Domain #1
Region A:
Residues: [1-88]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLNLLVNQE ELKRYLDEYG VWSKIFRALF VARNSKPLRS FCVHYAIKEL KEKTYNLELY  60
   61 QSLFEEFQDC FENEQLDVEW VESVTFHR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [89-239]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQNLEQLRRE LKAYKNNLIR ESIRAAQLDL ASFFADVGQF DSALRSYAKV REYCTNAGQI  60
   61 AHLSLELMRI SIWIGNYSHV LAFGSRAKST VSAAMELTSP IYAYCGLANF CLGDYEEALA 120
  121 HFLKVETDTS DGIITKTDIS VYISLCALAC W

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.522879
Match: 1na0A
Description: Designed protein cTPR3
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [240-422]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DHKRLIQELE RNEEFNALSD LDPSLRRCLQ AKCNRKYSLL LDTLQQNAQD YSLDMYLAPQ  60
   61 LTNLFSLIRE RSLLDYLIPY SALPFSKIAV DFHIDENFIE KNLLEIIEAK KLNGKVDSLQ 120
  121 KRVYIEPSSE PENFEDIKNI AQTSLLYSKA LYLQTLAAMN TENTDDEAPV IAQTNITAED 180
  181 SQN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.69897
Match: 1ufmA
Description: Solution structure of the PCI domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.29569167054278 bayes_pls_golite062009
DNA binding 4.90756541371868 bayes_pls_golite062009
nucleic acid binding 4.69183445184264 bayes_pls_golite062009
transcription factor activity 4.14166958134441 bayes_pls_golite062009
binding 3.52874320222492 bayes_pls_golite062009
sequence-specific DNA binding 2.48053910222825 bayes_pls_golite062009
hydrolase activity 2.30467124306022 bayes_pls_golite062009
transcription activator activity 2.29614125067822 bayes_pls_golite062009
transcription repressor activity 2.19033875364989 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.48055533524841 bayes_pls_golite062009
structure-specific DNA binding 1.33374581364046 bayes_pls_golite062009
small conjugating protein ligase activity 1.27763700765562 bayes_pls_golite062009
ubiquitin-protein ligase activity 1.12147035668008 bayes_pls_golite062009
transcription factor binding 0.83705247708153 bayes_pls_golite062009
acid-amino acid ligase activity 0.754042916649094 bayes_pls_golite062009
protein binding 0.753698599635855 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 0.486434906547244 bayes_pls_golite062009
double-stranded DNA binding 0.286130392009263 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.249771970501337 bayes_pls_golite062009
transferase activity 0.064832527337659 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle