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Protein Overview: CG3108-PA

General Information:
Name(s) found: CG3108-PA / FBpp0070798 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG3108 (CG3108, FBgn0029807). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:5671228..5675649. It has the cytological map location 5C2. Based on sequence similarity, it is predicted to have molecular function</span>: metallocarboxypeptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: proteolysis. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1132 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: proteolysis [IEA]
    Molecular Function: zinc ion binding [IEA]
    metallocarboxypeptidase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYNARSRGSA ANEGISPKRI VTIGSLLLVL GLNQVASMSL DRLALERNEL PADQQQQQQQ  60
   61 DVLVDNMKLT SIPSADSSDM YMLVPDTVAS QLEDTEHVNR NSIEADPESD PSGSSSSDML 120
  121 MLESDSSPAM QLVELPSDIT VAESQPETEH DTENDQQQPE SIEEHVVLMK PASQEAQLEQ 180
  181 TVDLATEAAP VPLNDELPED EESPAATESA VEELEKESEA AMDDQVPEES EIQPEQVQPG 240
  241 EYQSESDGEQ AETKPEIEAQ PEVEAQPEAE AQPEAEPQLE VEPQPEVESQ PEVESQPEVE 300
  301 AQPEVEPQSE VESQPEAESH SEPETQAEVE AQPEVESLPE AESQPEAESQ PEREPEVEAE 360
  361 KISDNEVDTT EASLMETLVE GIEDGLTAAM DNLVPEELAE ASDKQETELE SEDQQSPVTE 420
  421 AIEEQAVPEI EQEKEKEPEQ ITLADETEQD SAQPSNEEPV EIAPEQHTEA EIAPAKIPEE 480
  481 GKPEEEVQVE EESKPVEESK PEEEIKQQED AKPEEDDQNY AETQPAVTEV KPEETPADIP 540
  541 VEIPAEVPAE IPAEIPAEVP AEIPAESPAE IAAEVPAEIP AEIPAEIPAE TPAETHAEIP 600
  601 ADVPAQVVAE APAETPAETP AEVPAEIPSK VQDEIQSDST QAEPQVEKEA QQPEKETKPL 660
  661 ESSLLTTIIP MVMPQPQVPS QPLQVQDSVL NYVNASFMQQ QPSETDLPKT EEESPFNAHL 720
  721 RRYDGAQVWR IVVQTDKDKR MADELQSKYD GQLWKEVKQE VDYLLKPQVL AAAERHIRAA 780
  781 NLSRIVLIDN LQRVIEKENP PAEKIAELQN RKGHRLTWQA YHRLEDIHGF IDYMAKTYPD 840
  841 ICSTEIIGYS VEKRPLKILK ISNGNARNPG IWIDGGMHAR EWISPATVTY IANQLVEGWE 900
  901 DLPEHMRSIN WYIHPVANPD GYEYSHTTDR LWRKNMRAHG RQCPGVDLNR NFGYKWGGKG 960
  961 TSASPCSQTY RGSKAFSEPE TFYISKFISG FPRETFQAYL SFHSYGQYIL YPWGYDYQLT1020
 1021 QDRADLDRVA RQAGTSITKS TGVKYTVGSS ATTLYPAAGG SDDWAKGIAG IKYAYTIEMG1080
 1081 DTGRYGFVLP ARFIQYNGKD GVTFADTVAR AIAQGRGKSV ARNSSGSRRR GH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..227] MSA 3.259995 View MSA. No confident structure predictions are available.
    2 View Details [228..442] deduced N/A No confident structure predictions are available.
    3 View Details [443..564] deduced N/A No confident structure predictions are available.
    4 View Details [565..719] FFAS03 1.21 THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA
    5 View Details [720..1132] PSI-BLAST 137.0 HUMAN PROCARBOXYPEPTIDASE A2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • peptidase activity
    		•  4.786910294594 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  4.40766568731738 bayes_pls_golite062009
  • hydrolase activity
    		•  4.23257784904124 bayes_pls_golite062009
  • exopeptidase activity
    		•  3.28577934113028 bayes_pls_golite062009
  • metallopeptidase activity
    		•  2.76103081380105 bayes_pls_golite062009
  • carboxypeptidase activity
    		•  2.63658263814587 bayes_pls_golite062009
  • metalloexopeptidase activity
    		•  1.76058821499096 bayes_pls_golite062009
  • metallocarboxypeptidase activity
    		•  1.56827526553175 bayes_pls_golite062009
  • catalytic activity
    		•  1.3989281287879 bayes_pls_golite062009
  • binding
    		•  1.13031326446259 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.910234727191613 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
    		•  0.723243947871592 bayes_pls_golite062009
  • serine hydrolase activity
    		•  0.596149133958797 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  0.578572340123331 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.454707207494165 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.273337363793137 bayes_pls_golite062009
  • DNA binding
    		•  0.115087846898245 bayes_pls_golite062009
  • aminopeptidase activity
    		•  0.0966237570696103 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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