YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Catalysis of the hydrolysis of peptide bonds formed between L-amino acids. Catalysis of the hydrolysis of N-terminal amino acid residues from in a polypeptide chain. Catalysis of the hydrolysis of N-terminal amino acid residues from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. Catalysis of the hydrolysis of N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. Catalysis of the hydrolysis of a peptide bond not more than three residues from the C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). Catalysis of the release of the N-terminal residue from a tripeptide. Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain, in a reaction that requires a free N-terminal amino group, C-terminal carboxyl group or both.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: aminopeptidase activity
Acc: GO:0004177
Aspect: Molecular Function
Desc: Catalysis of the hydrolysis of N-terminal amino acid residues from in a polypeptide chain.
Proteins in PDR annotated with:
   This term: 194 [Search]
   Term or descendants: 205 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004177 - aminopeptidase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle