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Protein Overview: snk-PB, snk-PA

General Information:
Name(s) found: snk-PB / FBpp0111746 [FlyBase]
snk-PA / FBpp0082184 [FlyBase]
Description(s) found:
Found 35 descriptions.
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  • The gene snake is referred to in FlyBase by the symbol Dmel\snk (CG7996, FBgn0003450). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:8865887..8868492. It has the cytological map location 87D9. Based on sequence similarity, it is predicted to have molecular function</span>: serine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: Toll signaling pathway; protein processing. 56 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene snake is referred to in FlyBase by the symbol Dmel\snk (CG7996, FBgn0003450). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:8865887..8868492. It has the cytological map location 87D9. Based on sequence similarity, it is predicted to have molecular function</span>: serine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: Toll signaling pathway; protein processing. 56 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 435 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [TAS]
    Biological Process: Toll signaling pathway [IGI][NAS][TAS]
    proteolysis [IEA][NAS][TAS]
    maternal specification of dorsal/ventral axis, oocyte, germ-line encoded [TAS]
    dorsal/ventral axis specification [NAS][TAS]
    protein processing [IGI]
    Molecular Function: serine-type endopeptidase activity [ISS][NAS]
    serine-type peptidase activity [NAS]
    peptidase activity [TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIILWSLIVH LQLTCLHLIL QTPNLEALDA LEIINYQTTK YTIPEVWKEQ PVATIGEDVD  60
   61 DQDTEDEESY LKFGDDAEVR TSVSEGLHEG AFCRRSFDGR SGYCILAYQC LHVIREYRVH 120
  121 GTRIDICTHR NNVPVICCPL ADKHVLAQRI SATKCQEYNA AARRLHLTDT GRTFSGKQCV 180
  181 PSVPLIVGGT PTRHGLFPHM AALGWTQGSG SKDQDIKWGC GGALVSELYV LTAAHCATSG 240
  241 SKPPDMVRLG ARQLNETSAT QQDIKILIIV LHPKYRSSAY YHDIALLKLT RRVKFSEQVR 300
  301 PACLWQLPEL QIPTVVAAGW GRTEFLGAKS NALRQVDLDV VPQMTCKQIY RKERRLPRGI 360
  361 IEGQFCAGYL PGGRDTCQGD SGGPIHALLP EYNCVAFVVG ITSFGKFCAA PNAPGVYTRL 420
  421 YSYLDWIEKI AFKQH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..435] PSI-BLAST 64.39794 Crystal structure of the zymogen catalytic region of human MASP-2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • lipoprotein lipase activator activity
    		•  4.85421845425021 bayes_pls_golite062009
  • complement component C3b binding
    		•  4.5906847434156 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  4.30730942151523 bayes_pls_golite062009
  • complement binding
    		•  4.20610055582645 bayes_pls_golite062009
  • receptor activity
    		•  4.1674160063682 bayes_pls_golite062009
  • cell surface binding
    		•  3.9106077177681 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  3.49243532917035 bayes_pls_golite062009
  • eukaryotic cell surface binding
    		•  3.28622521020223 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  3.28438900479019 bayes_pls_golite062009
  • molecular transducer activity
    		•  3.22847008653352 bayes_pls_golite062009
  • signal transducer activity
    		•  3.22847008653352 bayes_pls_golite062009
  • heparin binding
    		•  3.18889412817519 bayes_pls_golite062009
  • glutamate receptor activity
    		•  3.10631263111076 bayes_pls_golite062009
  • protein binding
    		•  3.02592228806142 bayes_pls_golite062009
  • binding
    		•  2.97929690141955 bayes_pls_golite062009
  • polysaccharide binding
    		•  2.79319890241656 bayes_pls_golite062009
  • antigen binding
    		•  2.62020046296629 bayes_pls_golite062009
  • olfactory receptor activity
    		•  2.44203908212185 bayes_pls_golite062009
  • hydrolase activity
    		•  1.7928458193906 bayes_pls_golite062009
  • peptidase activity
    		•  1.58735485738801 bayes_pls_golite062009
  • enzyme regulator activity
    		•  1.44434463893416 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  1.31433180816931 bayes_pls_golite062009
  • pattern binding
    		•  1.26957983931218 bayes_pls_golite062009
  • peptide binding
    		•  1.24546307947399 bayes_pls_golite062009
  • glycoprotein binding
    		•  1.09315037798215 bayes_pls_golite062009
  • cytokine binding
    		•  1.07787494101375 bayes_pls_golite062009
  • opsonin binding
    		•  1.0527649340829 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.989017219131167 bayes_pls_golite062009
  • growth factor binding
    		•  0.86247435895783 bayes_pls_golite062009
  • cytokine receptor activity
    		•  0.78721893411676 bayes_pls_golite062009
  • peptide antigen binding
    		•  0.7841033460559 bayes_pls_golite062009
  • interleukin-2 binding
    		•  0.57419954221693 bayes_pls_golite062009
  • interleukin-2 receptor activity
    		•  0.527346341599 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.37481112933019 bayes_pls_golite062009
  • phospholipid binding
    		•  0.36876716174996 bayes_pls_golite062009
  • lipase activator activity
    		•  0.28126686684249 bayes_pls_golite062009
  • catalytic activity
    		•  0.252597265474331 bayes_pls_golite062009
  • enzyme inhibitor activity
    		•  0.02393250297214 bayes_pls_golite062009
  • enzyme activator activity
    		•  0.0100970089846147 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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