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Stops, prevents or reduces the activity of an enzyme. Stops, prevents or reduces the activity of dUTP pyrophosphatase. Stops, prevents or reduces the activity of alpha-amylase. Stops, prevents or reduces the activity of guanylate cyclase. Stops, prevents or reduces the activity of a telomerase. Telomerase catalyzes the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence. Stops, prevents or reduces the activity of any pectinesterase enzyme. Stops, prevents or reduces the activity of a ribonuclease, any enzyme that catalyzes the hydrolysis of phosphodiester bonds in chains of RNA. Stops, prevents or reduces the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule. Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of ATP to ADP and orthophosphate. Stops, prevents or reduces the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule. Stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds. Stops, prevents or reduces the activity of a lysozyme, an enzyme that hydrolyses the beta- (1,4) glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan. Stops, prevents or reduces the activity of ATP-hydrolyzing DNA topoisomerase. ATP-hydrolyzing DNA topoisomerase catalyzes the DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2. The stopping, prevention or reduction of the activity of the enzyme ornithine decarboxylase. Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. Stops, prevents or reduces the activity of a metalloenzyme. A metalloenzyme is any enzyme that contains metal. Stops, prevents or reduces the activity of deoxyribonuclease. Modulates the activity of an enzyme. Stops, prevents or reduces the activity of a ligase. Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of GTP to GDP and orthophosphate. Stops, prevents or reduces the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid. Stops, prevents or reduces the activity of histone deacetylase, which catalyzes of the removal of acetyl groups from histones, proteins complexed to DNA in chromatin and chromosomes.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: enzyme inhibitor activity
Acc: GO:0004857
Aspect: Molecular Function
Desc: Stops, prevents or reduces the activity of an enzyme.
Proteins in PDR annotated with:
   This term: 191 [Search]
   Term or descendants: 1067 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004857 - enzyme inhibitor activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle