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View Structure Prediction Details

Protein: snk-PB, snk-PA
Organism: Drosophila melanogaster
Length: 435 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for snk-PB, snk-PA.

Description E-value Query
Range
Subject
Range
gi|225309, gi|85... - gi|8632|emb|CAA28197.1| unnamed protein product [Drosophila melanogaster], pir||A24702 serine protei...
306.0 [0..1] [430..1]

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Predicted Domain #1
Region A:
Residues: [1-435]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIILWSLIVH LQLTCLHLIL QTPNLEALDA LEIINYQTTK YTIPEVWKEQ PVATIGEDVD  60
   61 DQDTEDEESY LKFGDDAEVR TSVSEGLHEG AFCRRSFDGR SGYCILAYQC LHVIREYRVH 120
  121 GTRIDICTHR NNVPVICCPL ADKHVLAQRI SATKCQEYNA AARRLHLTDT GRTFSGKQCV 180
  181 PSVPLIVGGT PTRHGLFPHM AALGWTQGSG SKDQDIKWGC GGALVSELYV LTAAHCATSG 240
  241 SKPPDMVRLG ARQLNETSAT QQDIKILIIV LHPKYRSSAY YHDIALLKLT RRVKFSEQVR 300
  301 PACLWQLPEL QIPTVVAAGW GRTEFLGAKS NALRQVDLDV VPQMTCKQIY RKERRLPRGI 360
  361 IEGQFCAGYL PGGRDTCQGD SGGPIHALLP EYNCVAFVVG ITSFGKFCAA PNAPGVYTRL 420
  421 YSYLDWIEKI AFKQH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.39794
Match: 1zjkA
Description: Crystal structure of the zymogen catalytic region of human MASP-2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
lipoprotein lipase activator activity 4.85421845425021 bayes_pls_golite062009
complement component C3b binding 4.5906847434156 bayes_pls_golite062009
transmembrane receptor activity 4.30730942151523 bayes_pls_golite062009
complement binding 4.20610055582645 bayes_pls_golite062009
receptor activity 4.1674160063682 bayes_pls_golite062009
cell surface binding 3.9106077177681 bayes_pls_golite062009
glycosaminoglycan binding 3.49243532917035 bayes_pls_golite062009
eukaryotic cell surface binding 3.28622521020223 bayes_pls_golite062009
G-protein coupled receptor activity 3.28438900479019 bayes_pls_golite062009
molecular transducer activity 3.22847008653352 bayes_pls_golite062009
signal transducer activity 3.22847008653352 bayes_pls_golite062009
heparin binding 3.18889412817519 bayes_pls_golite062009
glutamate receptor activity 3.10631263111076 bayes_pls_golite062009
protein binding 3.02592228806142 bayes_pls_golite062009
binding 2.97929690141955 bayes_pls_golite062009
polysaccharide binding 2.79319890241656 bayes_pls_golite062009
antigen binding 2.62020046296629 bayes_pls_golite062009
olfactory receptor activity 2.44203908212185 bayes_pls_golite062009
hydrolase activity 1.7928458193906 bayes_pls_golite062009
peptidase activity 1.58735485738801 bayes_pls_golite062009
enzyme regulator activity 1.44434463893416 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 1.31433180816931 bayes_pls_golite062009
pattern binding 1.26957983931218 bayes_pls_golite062009
peptide binding 1.24546307947399 bayes_pls_golite062009
glycoprotein binding 1.09315037798215 bayes_pls_golite062009
cytokine binding 1.07787494101375 bayes_pls_golite062009
opsonin binding 1.0527649340829 bayes_pls_golite062009
endopeptidase activity 0.989017219131167 bayes_pls_golite062009
growth factor binding 0.86247435895783 bayes_pls_golite062009
cytokine receptor activity 0.78721893411676 bayes_pls_golite062009
peptide antigen binding 0.7841033460559 bayes_pls_golite062009
interleukin-2 binding 0.57419954221693 bayes_pls_golite062009
interleukin-2 receptor activity 0.527346341599 bayes_pls_golite062009
carbohydrate binding 0.37481112933019 bayes_pls_golite062009
phospholipid binding 0.36876716174996 bayes_pls_golite062009
lipase activator activity 0.28126686684249 bayes_pls_golite062009
catalytic activity 0.252597265474331 bayes_pls_golite062009
enzyme inhibitor activity 0.02393250297214 bayes_pls_golite062009
enzyme activator activity 0.0100970089846147 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle