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Protein Overview: PpD3-PB, PpD3-PA...

General Information:
Name(s) found: FBpp0304082 [FlyBase]
PpD3-PB / FBpp0081607 [FlyBase]
PpD3-PA / FBpp0081606 [FlyBase]
Description(s) found:
Found 43 descriptions.
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  • type=protein; loc=3R:join(5573940..5574123,5574334..5574575,5574632..5574782,5574848..5574969,5575028..5575298,5575363..5575813,5575870..5575951,5576007..5576066); ID=FBpp0304082; name=PpD3-PC; parent=FBgn0005777,FBtr0331693; dbxref=FlyBase:FBpp0304082,FlyBase_Annotation_IDs:CG8402-PC,REFSEQ:NP_001262433,GB_protein:AGB95815; MD5=a415ef60ecb6f8620b8171cb70e22182; length=520; release=r5.56; species=Dmel; [FlyBase]
  • The gene Protein phosphatase D3 is referred to in FlyBase by the symbol Dmel\PpD3 (CG8402, FBgn0005777). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5573597..5576822. It has the cytological map location 85E6. Based on sequence similarity, it is predicted to have molecular function</span>: protein serine/threonine phosphatase activity. There is experimental evidence that it is involved in the biological process</span>: mitotic cell cycle. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene Protein phosphatase D3 is referred to in FlyBase by the symbol Dmel\PpD3 (CG8402, FBgn0005777). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5573597..5576822. It has the cytological map location 85E6. Based on sequence similarity, it is predicted to have molecular function</span>: protein serine/threonine phosphatase activity. There is experimental evidence that it is involved in the biological process</span>: mitotic cell cycle. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 520 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    cytoplasm [IEA]
    Biological Process: protein amino acid dephosphorylation [IEA][ISS][NAS]
    mitotic cell cycle [IMP]
    Molecular Function: protein serine/threonine phosphatase activity [ISS][NAS]
    metal ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSELEVQK AADCQQEAKV PASVEITGSK QPEEDTNART KAELDFAAAE QYKNQGNEML  60
   61 KTKEFSKAID MYTKAIELHP NSAIYYANRS LAHLRQESFG FALQDGVSAV KADPAYLKGY 120
  121 YRRAAAHMSL GKFKQALCDF EFVAKCRPND KDAKLKFTEC NKIVKMRAFE RAIAVDKPEK 180
  181 TLSEMYSDME NITIEDDYKG PQLEDGKVTL KFMKELMEHY KAQKRLHRKF AYKILCEIDT 240
  241 YMRAQPSLVD ITVPDEEKFT ICGDIHGQFY DLMNIFEING LPSEKNPYLF NGDFVDRGSF 300
  301 SVECIFTLFG FKLLYPNHFF LARGNHESIN MNQMYGFTGE VTAKYTSAMA DIFTQVFNWL 360
  361 PLCHCINQKI LVMHGGLFST EDVTLDHIRR IERNCQPPEE GLMCELLWSD PQQWMGLGQS 420
  421 KRGVGIQFGP DVTEKFCKDN NLDYIIRSHE VKDMGYEVAH NGKCITVFSA PNYCDTMGNM 480
  481 GAFITITGNN LKPNYKSFEA VPHPDVKPMA YANSLMNWLA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..520] PSI-BLAST 100.0 PP5 structure

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphoprotein phosphatase activity
    		•  11.6417995308386 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  10.6440947462013 bayes_pls_golite062009
  • phosphatase activity
    		•  10.5525832502704 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  10.3702645338723 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  9.02791306892273 bayes_pls_golite062009
  • calcium-dependent protein serine/threonine phosphatase activity
    		•  6.04386346716682 bayes_pls_golite062009
  • myosin phosphatase activity
    		•  4.20017318089013 bayes_pls_golite062009
  • hydrolase activity
    		•  3.13006743434485 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.36571535004008 bayes_pls_golite062009
  • DNA binding
    		•  1.95874073664777 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.72745783719415 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.68552051869632 bayes_pls_golite062009
  • kinase activity
    		•  1.67788383575784 bayes_pls_golite062009
  • structural molecule activity
    		•  1.5850868178597 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.57807175808088 bayes_pls_golite062009
  • protein kinase activity
    		•  1.4514460578232 bayes_pls_golite062009
  • binding
    		•  1.44538582463569 bayes_pls_golite062009
  • catalytic activity
    		•  1.39852585255405 bayes_pls_golite062009
  • transferase activity
    		•  1.3407391509244 bayes_pls_golite062009
  • protein binding
    		•  1.33435965029646 bayes_pls_golite062009
  • transcription factor activity
    		•  1.21805666483342 bayes_pls_golite062009
  • receptor activity
    		•  1.19949789380979 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.08090214431427 bayes_pls_golite062009
  • signal transducer activity
    		•  1.08090214431427 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.841959344808827 bayes_pls_golite062009
  • ligase activity
    		•  0.825764637499128 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.66803085638835 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.532407342912695 bayes_pls_golite062009
  • transcription factor binding
    		•  0.518146612491969 bayes_pls_golite062009
  • RNA binding
    		•  0.497066934302855 bayes_pls_golite062009
  • procollagen-proline dioxygenase activity
    		•  0.482467028485988 bayes_pls_golite062009
  • procollagen-proline 4-dioxygenase activity
    		•  0.482467028485988 bayes_pls_golite062009
  • peptidyl-proline dioxygenase activity
    		•  0.482467028485988 bayes_pls_golite062009
  • peptidyl-proline 4-dioxygenase activity
    		•  0.482467028485988 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.30464889749774 bayes_pls_golite062009
  • peptide binding
    		•  0.280393897104229 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.192538429095884 bayes_pls_golite062009
  • transcription activator activity
    		•  0.0593768116971065 bayes_pls_golite062009
  • small GTPase binding
    		•  0.0394561704024805 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.0274922636265745 bayes_pls_golite062009
  • GTPase binding
    		•  0.0230090675760397 bayes_pls_golite062009
  • GTPase regulator activity
    		•  0.0182110291463968 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle