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Protein Overview: Ance-5-PA

General Information:
Name(s) found: Ance-5-PA / FBpp0072325 [FlyBase]
Description(s) found:
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  • gi|7291869|gb|AAF47288.1| Ance-5 [Drosophila melanogaster] [NCBI NR]
  • gi|24762773|ref|NP_573392.2| Ance-5 [Drosophila melanogaster] [NCBI NR]
  • gi|201066167|gb|ACH92493.1| FI09601p [Drosophila melanogaster] [NCBI NR]
  • The gene Ance-5 is referred to in FlyBase by the symbol Dmel\Ance-5 (CG10142, FBgn0035076). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:20776151..20778545. It has the cytological map location 60E5. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: metallopeptidase activity; peptidyl-dipeptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: proteolysis. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG10142-PA translation from_gene[CG10142 Ance-5 FBgn0035076] seq_release:3 mol_weight=72922 cds_boundaries:(2R:19,932,318..19,934,481[-]) aa_length:628 transcript_info:[CG10142-RA seq_release:3] gene_info:[gene symbol:Ance-5 FBgn0035076 gene_boundarie [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9W0Z1) CG10142 protein [DrosMelano7227.FASTAC.txt]
  • (AE003465) CG10142 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG10142-PA [Drosophila melanogaster]gi|24762773|ref|NP_573392.2| CG10142-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:complement(20776268..20776284,20776345..20776658,20776718..20777284,20777446..20778434); ID=FBpp0072325; name=Ance-5-PA; parent=FBgn0035076,FBtr0072420; dbxref=FlyBase:FBpp0072325,FlyBase_Annotation_IDs:CG10142-PA,GB_protein:AAF47288. [fly-100309-contam.fasta]
  • CG10142-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Ance-5 CG10142-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:complement(20776268..20776284,20776345..20776658,20776718..20777284,20777446..20778434); ID=FBpp0072325; name=Ance-5-PA; parent=FBgn0035076,FBtr0072420; dbxref=FlyBase:FBpp0072325,FlyBase_Annotation_IDs:CG10142-PA,GB_protein:AAF47288.1,REFSEQ:NP_573392,GB_protein:AAF47288; MD5=1df8b9ecf34680f3d9c80a1427bc8740; length=628; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:complement(20776268..20776284,20776345..20776658,20776718..20777284,20777446..20778434); ID=FBpp0072325; name=Ance-5-PA; parent=FBgn0035076,FBtr0072420; dbxref=FlyBase:FBpp0072325,FlyBase_Annotation_IDs:CG10142-PA,GB_protein:AAF47288.1,REFSEQ:NP_573392,GB_protein:AAF47288; MD5=1df8b9ecf34680f3d9c80a1427bc8740; length=628; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Ance-5 OS=Drosophila melanogaster GN=Ance-5 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:complement(20776268..20776284,20776345..20776658,20776718..20777284,20777446..20778434); ID=FBpp0072325; name=Ance-5-PA; parent=FBgn0035076,FBtr0072420; dbxref=FlyBase:FBpp0072325,FlyBase_Annotation_IDs:CG10142-PA,GB_protein:AAF47288.1,REFSEQ:NP_573392,GB_protein:AAF47288,FlyMine:FBpp0072325,modMine:FBpp0072325; MD5=1df8b9ecf34680f3d9c80a1427bc8740; length=628; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:complement(join(24889923..24890911,24889195..24889761,24888822..24889135,24888745..24888761)); ID=FBpp0072325; name=Ance-5-PA; parent=FBgn0035076,FBtr0072420; dbxref=FlyBase:FBpp0072325,FlyBase_Annotation_IDs:CG10142-PA,GB_protein:AAF47288.1,REFSEQ:NP_573392,GB_protein:AAF47288,FlyMine:FBpp0072325,modMine:FBpp0072325; MD5=1df8b9ecf34680f3d9c80a1427bc8740; length=628; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:complement(join(24889923..24890911,24889195..24889761,24888822..24889135,24888745..24888761)); ID=FBpp0072325; name=Ance-5-PA; parent=FBgn0035076,FBtr0072420; dbxref=FlyBase:FBpp0072325,FlyBase_Annotation_IDs:CG10142-PA,GB_protein:AAF47288.1,REFSEQ:NP_573392,GB_protein:AAF47288,FlyMine:FBpp0072325,modMine:FBpp0072325; MD5=1df8b9ecf34680f3d9c80a1427bc8740; length=628; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0072325 type=protein; loc=2R:complement(join(24889923..24890911,24889195..24889761,24888822..24889135,24888745..24888761)); ID=FBpp0072325; name=Ance-5-PA; parent=FBgn0035076,FBtr0072420; dbxref=FlyBase:FBpp0072325,FlyBase_Annotation_IDs:CG10142-PA,GB_protein:AAF47288.1,REFSEQ:NP_573392,GB_protein:AAF47288,FlyMine:FBpp0072325,modMine:FBpp0072325; MD5=1df8b9ecf34680f3d9c80a1427bc8740; length=628; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:complement(join(24889923..24890911,24889195..24889761,24888822..24889135,24888745..24888761)); ID=FBpp0072325; name=Ance-5-PA; parent=FBgn0035076,FBtr0072420; dbxref=FlyBase:FBpp0072325,FlyBase_Annotation_IDs:CG10142-PA,GB_protein:AAF47288.1,REFSEQ:NP_573392,GB_protein:AAF47288,UniProt/TrEMBL:Q9W0Z1,FlyMine:FBpp0072325,modMine:FBpp0072325; MD5=1df8b9ecf34680f3d9c80a1427bc8740; length=628; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 628 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    Biological Process: proteolysis [IEA]
    Molecular Function: [NOT]peptidyl-dipeptidase activity [IEA][NAS]
    [NOT]peptidase activity [ISS]
    metallopeptidase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLPFLGVSL ILLLSVTFGI GQSSYELATK QILDRAKDRM RHVWSLNRRI FVQLTAKGKS  60
   61 PLGGQVLNSK LEVEAETYRL FYDLAGNLSV VSVAELNDPL LRRRVQRMAK LQLQGLRPKD 120
  121 YEQAKDLLRQ IHNFVNGPLV CPYEDCSARG SLAMYPQIMN KNMHTKLYED LVINWKAWRR 180
  181 AINEKDVAKN TFIGYVRLLR IAATYNGHVT PSRTWYLNYD TENFQAEMEA VVWEIMPLYR 240
  241 ELHAYLRREV QAAYPKADTK SDGAISAPIM DQILSQDWYP HQFFRTPHQG RQHQLPSVHR 300
  301 RLEEVLVTPV KINRKAAEFF ESLGLMVMPN IFYDRFSRRM NDEEGGAECK SQVYYFPPDV 360
  361 ALRYCPKLDY KKMMQIHGTM AELQYHLYKM QLPFGLDTEP CPGFGAAIAE TVILASGTPR 420
  421 HLHRLHILLN DSLTEEQSLN RLFRMGVHTL IAVPQYFIND KFLVDVMDGR IGVKDYNCAY 480
  481 WGLQDKFAGV QPPLQRLNKD FDVDFKFYRG LNPETSNTKK FLAEILGFQF YRSFCLASGQ 540
  541 YKPGDPNFPL HNCDFYDSKE AGKKIRDMMQ LGATRHWRDV MEIATGERKL SGRGILEYFA 600
  601 PLFTWLKERN KQLDIEPGWD ADELCRRD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..628] PSI-BLAST 176.0 Angiotensin convering enzyme

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  5.33358263548929 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  4.99457783001146 bayes_pls_golite062009
  • bradykinin receptor binding
    		•  4.68498310889748 bayes_pls_golite062009
  • endopeptidase activity
    		•  4.16532996235931 bayes_pls_golite062009
  • metallopeptidase activity
    		•  3.94798058866011 bayes_pls_golite062009
  • metalloendopeptidase activity
    		•  3.43236442601127 bayes_pls_golite062009
  • peptidyl-dipeptidase activity
    		•  3.15882456934259 bayes_pls_golite062009
  • hydrolase activity
    		•  2.61181165622708 bayes_pls_golite062009
  • exopeptidase activity
    		•  2.07461908743946 bayes_pls_golite062009
  • integrin binding
    		•  1.58328929324965 bayes_pls_golite062009
  • binding
    		•  1.55761777216628 bayes_pls_golite062009
  • protein complex binding
    		•  1.52308144668596 bayes_pls_golite062009
  • epoxide hydrolase activity
    		•  1.37998417474643 bayes_pls_golite062009
  • transporter activity
    		•  1.28982382930122 bayes_pls_golite062009
  • receptor binding
    		•  1.20826493144754 bayes_pls_golite062009
  • ether hydrolase activity
    		•  1.18753073809881 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.0688261398267 bayes_pls_golite062009
  • catalytic activity
    		•  0.891187593353827 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.798767221679673 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.543737159152136 bayes_pls_golite062009
  • protein binding
    		•  0.530727556830171 bayes_pls_golite062009
  • zinc ion binding
    		•  0.49304764842799 bayes_pls_golite062009
  • hydrolase activity, acting on ether bonds
    		•  0.457157426475929 bayes_pls_golite062009
  • serine hydrolase activity
    		•  0.393080846858665 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  0.374597710524442 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  0.369102282817767 bayes_pls_golite062009
  • serine-type endopeptidase activity
    		•  0.252655558968584 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.241890854867053 bayes_pls_golite062009
  • aminopeptidase activity
    		•  0.21808506596674 bayes_pls_golite062009
  • transition metal ion binding
    		•  0.21514043665594 bayes_pls_golite062009
  • signal transducer activity
    		•  0.120905338073793 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.120905338073793 bayes_pls_golite062009
  • angiotensin receptor activity
    		•  0.0133022345809808 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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