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Protein Overview: Elongin-C-PA, El...

General Information:
Name(s) found: Elongin-C-PB / FBpp0085725 [FlyBase]
Elongin-C-PA / FBpp0085724 [FlyBase]
Description(s) found:
Found 38 descriptions.
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  • The gene Elongin C is referred to in FlyBase by the symbol Dmel\Elongin-C (CG9291, FBgn0023211). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:15332590..15333797. It has the cytological map location 56D7. Based on sequence similarity, it is predicted to have molecular function</span>: transcription elongation regulator activity. There is experimental evidence that it is involved in the biological process</span>: dendrite morphogenesis. 6 alleles are reported. The phenotype of these alleles is annotated with: dendrite. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene Elongin C is referred to in FlyBase by the symbol Dmel\Elongin-C (CG9291, FBgn0023211). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:15332590..15333797. It has the cytological map location 56D7. Based on sequence similarity, it is predicted to have molecular function</span>: transcription elongation regulator activity. There is experimental evidence that it is involved in the biological process</span>: dendrite morphogenesis. 6 alleles are reported. The phenotype of these alleles is annotated with: dendrite. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 117 amino acids

    Gene Ontology:
    Cellular Component: transcription elongation factor complex [ISS]
    Biological Process: ubiquitin-dependent protein catabolic process [IEA]
    dendrite morphogenesis [IMP]
    Molecular Function: transcription elongation regulator activity [ISS]
    protein binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIAMDEQRGD KIYGGCEGPD AMYVKLISSD GHEFVVKREH ALTSGTIRAM LSGPGQFAEN  60
   61 EANEVHFREI PSHVLQKVCM YFTYKVRYTN SSTEIPEFPI APEIALELLM AANFLDC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..117] PSI-BLAST 38.154902 Elongin C

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription elongation regulator activity
    		•  7.53002625989446 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  6.78934422958647 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  6.52079977531395 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  5.78412146341235 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  4.95822114853319 bayes_pls_golite062009
  • transcription regulator activity
    		•  4.03732153795237 bayes_pls_golite062009
  • DNA binding
    		•  3.50992893425527 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.39650042677839 bayes_pls_golite062009
  • transcription factor activity
    		•  2.77967244868934 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  2.75167015020269 bayes_pls_golite062009
  • binding
    		•  2.73171412378045 bayes_pls_golite062009
  • cation channel activity
    		•  2.69496177380647 bayes_pls_golite062009
  • transporter activity
    		•  2.69283272202719 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  2.6326729238119 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  2.62698068681382 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  2.62598337348177 bayes_pls_golite062009
  • potassium channel activity
    		•  2.60418200634863 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.57638436739741 bayes_pls_golite062009
  • gated channel activity
    		•  2.55327516550249 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.55217077864016 bayes_pls_golite062009
  • ion channel activity
    		•  2.55187860471911 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.52366517282235 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  2.49612586394403 bayes_pls_golite062009
  • channel activity
    		•  2.47974023065334 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  2.47974023065334 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.47370185025265 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.46166567746833 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  2.36236066628439 bayes_pls_golite062009
  • ligase activity
    		•  1.75579073151181 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.71028791830657 bayes_pls_golite062009
  • protein binding
    		•  1.38558174459188 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.933012980583336 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.784594789263781 bayes_pls_golite062009
  • delayed rectifier potassium channel activity
    		•  0.72427436100801 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.278232864316812 bayes_pls_golite062009
  • catalytic activity
    		•  0.112500532859479 bayes_pls_golite062009
  • chromatin binding
    		•  0.0908724449159477 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.033499769837058 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle