YRC Public Data Repository - Protein Structure Prediction

Protein:	Elongin-C-PA, El...
Organism:	Drosophila melanogaster
Length:	117 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Elongin-C-PA, El....

Description	E-value	Query Range	Subject Range
gi\|114620737 - gi\|114620737\|ref\|XP_519811.2\| PREDICTED: similar to elongation factor SIII p15 subunit [Pan troglody...	155.0	[0..10]	[117..113]
gi\|109086753 - gi\|109086753\|ref\|XP_001087401.1\| PREDICTED: similar to transcription elongation factor B (SIII), pol...	155.0	[0..4]	[117..45]
gi\|54695684, gi\|... - gi\|61368803\|gb\|AAX43239.1\| transcription elongation factor B polypeptide 1 [synthetic construct], gi...	154.0	[0..10]	[117..5]
gi\|109503634 - gi\|109503634\|ref\|XP_001053854.1\| PREDICTED: similar to transcription elongation factor B (SIII), pol...	154.0	[0..10]	[117..29]
gi\|53133354, gi\|... - gi\|56119006\|ref\|NP_001007889.1\| transcription elongation factor B (SIII), polypeptide 1 (15kDa, elon... gi\|55630822, gi\|... - gi\|55630822\|ref\|XP_519811.1\| PREDICTED: similar to elongation factor SIII p15 subunit [Pan troglodyt... gi\|147899211, gi... - gi\|32766703\|gb\|AAH55268.1\| Tceb1-prov protein [Xenopus laevis], gi\|147899211\|ref\|NP_001080128.1\| elo... gi\|57107789 - gi\|57107789\|ref\|XP_535104.1\| PREDICTED: similar to transcription elongation factor B (SIII), polypep... ENSMMUG000000051... - null, null ENSCJAT00000001073 - null tr\|G3H9C9\|G3H9C9... - Transcription elongation factor B polypeptide 1 OS=Cricetulus griseus GN=I79_006997 PE=4 SV=1 ELOC_BOVIN - Transcription elongation factor B polypeptide 1 OS=Bos taurus GN=TCEB1 PE=3 SV=1 gi\|134026008, gi... - gi\|89273855\|emb\|CAJ81641.1\| transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin ... gi\|542140578\|ref... - PREDICTED: transcription elongation factor B polypeptide 1 isoform X4 [Zonotrichia albicollis], PRED... gi\|224046386 - gi\|224046386\|ref\|XP_002199345.1\| PREDICTED: transcription elongation factor B (SIII), polypeptide 1 ... ELOC_MOUSE - Transcription elongation factor B polypeptide 1 OS=Mus musculus GN=Tceb1 PE=1 SV=1 gi\|221220584 - gi\|221220584\|gb\|ACM08953.1\| Transcription elongation factor B polypeptide 1 [Salmo salar] TCEB1 - transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) gi\|225706010 - gi\|225706010\|gb\|ACO08851.1\| Transcription elongation factor B polypeptide 1 [Osmerus mordax] gi\|225703494, gi... - gi\|225704260\|gb\|ACO07976.1\| Transcription elongation factor B polypeptide 1 [Oncorhynchus mykiss], g... gi\|157928825, gi... - gi\|208967949\|dbj\|BAG73813.1\| transcription elongation factor B (SIII), polypeptide 1 [synthetic cons... gi\|194036622 - gi\|194036622\|ref\|XP_001927356.1\| PREDICTED: similar to elongation factor SIII p15 subunit [Sus scrof... gi\|126321268 - gi\|126321268\|ref\|XP_001378182.1\| PREDICTED: similar to elongation factor SIII p15 subunit [Monodelph... gi\|194214831 - gi\|194214831\|ref\|XP_001493068.2\| PREDICTED: similar to elongation factor SIII p15 subunit [Equus cab... gi\|226372290 - gi\|226372290\|gb\|ACO51770.1\| Transcription elongation factor B polypeptide 1 [Rana catesbeiana] tr\|F8V3I9\|F8V3I9... - Transcription elongation factor B polypeptide 1 OS=Felis catus GN=TCEB1 PE=2 SV=1 ELOC_RAT - Transcription elongation factor B polypeptide 1 OS=Rattus norvegicus GN=Tceb1 PE=1 SV=1	154.0	[0..10]	[117..5]
gi\|182889662, gi... - gi\|73088652\|ref\|NP_001002440.2\| transcription elongation factor B (SIII), polypeptide 1 [Danio rerio...	153.0	[0..10]	[117..5]
gi\|91087169 - gi\|91087169\|ref\|XP_975384.1\| PREDICTED: similar to AGAP011535-PA [Tribolium castaneum]	152.0	[0..5]	[117..6]
AGAP011535-PA - transcription elongation factor B, polypeptide 1\|protein_coding\|3L:26900767:26902655:1\|gene:AGAP0115... gi\|55244288, gi\|... - gi\|58379541\|ref\|XP_309973.2\| AGAP011535-PA [Anopheles gambiae str. PEST], gi\|55244288\|gb\|EAA05684.3\|...	150.0	[0..10]	[117..10]

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Predicted Domain #1

Region A:
Residues: [1-117]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIAMDEQRGD KIYGGCEGPD AMYVKLISSD GHEFVVKREH ALTSGTIRAM LSGPGQFAEN  60
   61 EANEVHFREI PSHVLQKVCM YFTYKVRYTN SSTEIPEFPI APEIALELLM AANFLDC

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	38.154902
Match:	1vcbB
Description:	Elongin C
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription elongation regulator activity	7.53002625989446	bayes_pls_golite062009
ubiquitin-protein ligase activity	6.78934422958647	bayes_pls_golite062009
small conjugating protein ligase activity	6.52079977531395	bayes_pls_golite062009
acid-amino acid ligase activity	5.78412146341235	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	4.95822114853319	bayes_pls_golite062009
transcription regulator activity	4.03732153795237	bayes_pls_golite062009
DNA binding	3.50992893425527	bayes_pls_golite062009
nucleic acid binding	3.39650042677839	bayes_pls_golite062009
transcription factor activity	2.77967244868934	bayes_pls_golite062009
voltage-gated cation channel activity	2.75167015020269	bayes_pls_golite062009
binding	2.73171412378045	bayes_pls_golite062009
cation channel activity	2.69496177380647	bayes_pls_golite062009
transporter activity	2.69283272202719	bayes_pls_golite062009
voltage-gated potassium channel activity	2.6326729238119	bayes_pls_golite062009
voltage-gated ion channel activity	2.62698068681382	bayes_pls_golite062009
voltage-gated channel activity	2.62598337348177	bayes_pls_golite062009
potassium channel activity	2.60418200634863	bayes_pls_golite062009
transmembrane transporter activity	2.57638436739741	bayes_pls_golite062009
gated channel activity	2.55327516550249	bayes_pls_golite062009
substrate-specific transporter activity	2.55217077864016	bayes_pls_golite062009
ion channel activity	2.55187860471911	bayes_pls_golite062009
cation transmembrane transporter activity	2.52366517282235	bayes_pls_golite062009
substrate-specific channel activity	2.49612586394403	bayes_pls_golite062009
channel activity	2.47974023065334	bayes_pls_golite062009
passive transmembrane transporter activity	2.47974023065334	bayes_pls_golite062009
ion transmembrane transporter activity	2.47370185025265	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.46166567746833	bayes_pls_golite062009
metal ion transmembrane transporter activity	2.36236066628439	bayes_pls_golite062009
ligase activity	1.75579073151181	bayes_pls_golite062009
transcription repressor activity	1.71028791830657	bayes_pls_golite062009
protein binding	1.38558174459188	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.933012980583336	bayes_pls_golite062009
structure-specific DNA binding	0.784594789263781	bayes_pls_golite062009
delayed rectifier potassium channel activity	0.72427436100801	bayes_pls_golite062009
sequence-specific DNA binding	0.278232864316812	bayes_pls_golite062009
catalytic activity	0.112500532859479	bayes_pls_golite062009
chromatin binding	0.0908724449159477	bayes_pls_golite062009
double-stranded DNA binding	0.033499769837058	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: