Protein Overview: elk-PA

General Information:
Name(s) found:	elk-PA / FBpp0085981 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|21627052\|gb\|AAF57772.2\| eag-like K[+] channel [Drosophila melanogaster] [NCBI NR] gi\|17136946\|ref\|NP_477009.1\| eag-like K[+] channel [Drosophila melanogaster] [NCBI NR] The gene eag-like K<sup>+</sup> channel is referred to in FlyBase by the symbol Dmel\elk (CG5076, FBgn0011589). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:13761452..13813097. It has the cytological map location 54F4-55A2. It is reported to have molecular function</span>: voltage-gated potassium channel activity; potassium channel activity. It is reported to be involved in the biological process</span>: potassium ion transport. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG5076-PA translation from_gene[CG5076 elk FBgn0011589] seq_release:3 mol_weight=141380 cds_boundaries:(2R:12,962,029..12,989,142[+]) aa_length:1284 transcript_info:[CG5076-RA seq_release:3] gene_info:[gene symbol:elk FBgn0011589 gene_boundaries:(2R:1 [hmr_yeast5_DM3-1_pombe.fasta] (Q9V899) CG5076 protein [DrosMelano7227.FASTAC.txt] CG5076-PA [Drosophila melanogaster]gi\|17136946\|ref\|NP_477009.1\| CG5076-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=2R:join(13785809..13785884,13789213..13789323,13789465..13789584,13791047..13791184,13795152..13795411,13795871..13796099,13796585..13796748,13800183..13800384,13801606..13801785,13802292..13802410,13802919..13802999,13806253..13806348,1 [fly-100309-contam.fasta] eag-like K[+] channel CG5076-PA [Drosophila melanogaster] [nr-271106-contam.fasta] CG5076-PA [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2R:join(13785809..13785884,13789213..13789323,13789465..13789584,13791047..13791184,13795152..13795411,13795871..13796099,13796585..13796748,13800183..13800384,13801606..13801785,13802292..13802410,13802919..13802999,13806253..13806348,13808647..13808800,13809404..13809528,13811126..13812925); ID=FBpp0085981; name=elk-PA; parent=FBgn0011589,FBtr0086802; dbxref=FlyBase:FBpp0085981,FlyBase_Annotation_IDs:CG5076-PA,GB_protein:AAF57772.2,REFSEQ:NP_477009,GB_protein:AAF57772; MD5=2eb52afd44670aa22862cbef6bab612a; length=1284; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2R:join(13785809..13785884,13789213..13789323,13789465..13789584,13791047..13791184,13795152..13795411,13795871..13796099,13796585..13796748,13800183..13800384,13801606..13801785,13802292..13802410,13802919..13802999,13806253..13806348,13808647..13808800,13809404..13809528,13811126..13812925); ID=FBpp0085981; name=elk-PA; parent=FBgn0011589,FBtr0086802; dbxref=FlyBase:FBpp0085981,FlyBase_Annotation_IDs:CG5076-PA,GB_protein:AAF57772.2,REFSEQ:NP_477009,GB_protein:AAF57772; MD5=2eb52afd44670aa22862cbef6bab612a; length=1284; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Eag-like K[+] channel OS=Drosophila melanogaster GN=elk PE=4 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2R:join(13785809..13785884,13789213..13789323,13789465..13789584,13791047..13791184,13795152..13795411,13795871..13796099,13796585..13796748,13800183..13800384,13801606..13801785,13802292..13802410,13802919..13802999,13806253..13806348,13808647..13808800,13809404..13809528,13811126..13812925); ID=FBpp0085981; name=elk-PA; parent=FBgn0011589,FBtr0086802; dbxref=FlyBase:FBpp0085981,FlyBase_Annotation_IDs:CG5076-PA,GB_protein:AAF57772.2,REFSEQ:NP_477009,GB_protein:AAF57772,FlyMine:FBpp0085981,modMine:FBpp0085981; MD5=2eb52afd44670aa22862cbef6bab612a; length=1284; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2R:join(17898304..17898379,17901708..17901818,17901960..17902079,17903542..17903679,17907647..17907906,17908366..17908594,17909080..17909243,17912678..17912879,17914101..17914280,17914787..17914905,17915414..17915494,17918748..17918843,17921142..17921295,17921899..17922023,17923621..17925420); ID=FBpp0085981; name=Elk-PA; parent=FBgn0011589,FBtr0086802; dbxref=FlyBase:FBpp0085981,FlyBase_Annotation_IDs:CG5076-PA,GB_protein:AAF57772.2,REFSEQ:NP_477009,GB_protein:AAF57772,FlyMine:FBpp0085981,modMine:FBpp0085981; MD5=2eb52afd44670aa22862cbef6bab612a; length=1284; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2R:join(17898304..17898379,17901708..17901818,17901960..17902079,17903542..17903679,17907647..17907906,17908366..17908594,17909080..17909243,17912678..17912879,17914101..17914280,17914787..17914905,17915414..17915494,17918748..17918843,17921142..17921295,17921899..17922023,17923621..17925420); ID=FBpp0085981; name=Elk-PA; parent=FBgn0011589,FBtr0086802; dbxref=FlyBase:FBpp0085981,FlyBase_Annotation_IDs:CG5076-PA,GB_protein:AAF57772.2,REFSEQ:NP_477009,GB_protein:AAF57772,FlyMine:FBpp0085981,modMine:FBpp0085981; MD5=2eb52afd44670aa22862cbef6bab612a; length=1284; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Eag-like K[+] channel, isoform A OS=Drosophila melanogaster GN=Elk PE=1 SV=1 [DROME.fasta.20160308] FBpp0085981 type=protein; loc=2R:join(17898304..17898379,17901708..17901818,17901960..17902079,17903542..17903679,17907647..17907906,17908366..17908594,17909080..17909243,17912678..17912879,17914101..17914280,17914787..17914905,17915414..17915494,17918748..17918843,17921142..17921295,17921899..17922023,17923621..17925420); ID=FBpp0085981; name=Elk-PA; parent=FBgn0011589,FBtr0086802; dbxref=FlyBase:FBpp0085981,FlyBase_Annotation_IDs:CG5076-PA,GB_protein:AAF57772.2,REFSEQ:NP_477009,GB_protein:AAF57772,FlyMine:FBpp0085981,modMine:FBpp0085981; MD5=2eb52afd44670aa22862cbef6bab612a; length=1284; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2R:join(17898304..17898379,17901708..17901818,17901960..17902079,17903542..17903679,17907647..17907906,17908366..17908594,17909080..17909243,17912678..17912879,17914101..17914280,17914787..17914905,17915414..17915494,17918748..17918843,17921142..17921295,17921899..17922023,17923621..17925420); ID=FBpp0085981; name=Elk-PA; parent=FBgn0011589,FBtr0086802; dbxref=FlyBase:FBpp0085981,FlyBase_Annotation_IDs:CG5076-PA,GB_protein:AAF57772.2,REFSEQ:NP_477009,GB_protein:AAF57772,UniProt/TrEMBL:A1ZB14,FlyMine:FBpp0085981,modMine:FBpp0085981; MD5=2eb52afd44670aa22862cbef6bab612a; length=1284; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1284 amino acids
Gene Ontology:
Cellular Component:	voltage-gated potassium channel complex [NAS] membrane [IEA]
Biological Process:	potassium ion transport [IEA][NAS] transmembrane transport [IEA] two-component signal transduction system (phosphorelay) [IEA] regulation of transcription, DNA-dependent [IEA]
Molecular Function:	two-component sensor activity [IEA] voltage-gated potassium channel activity [IEA][NAS] potassium channel activity [NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPARKGLLAP QNTFLDTIAT RFDGTHSNFV LGNAQANGNP IVYCSDGFVD LTGYSRAQIM  60
   61 QKGCSCHFLY GPDTKEEHKQ QIEKSLSNKM ELKLEVIFYK KEGAPFWCLF DIVPIKNEKR 120
  121 DVVLFLASHK DITHTKMLEM NVNEECDSVF ALTAALLGAR FRAGSNAGML GLGGLPGLGG 180
  181 PAASDGDTEA GEGNNLDVPA GCNMGRRRSR AVLYQLSGHY KPEKGGVKTK LKLGNNFMHS 240
  241 TEAPFPEYKT QSIKKSRLIL PHYGVFKGIW DWVILVATFY VALMVPYNAA FAKADRQTKV 300
  301 SDVIVEALFI VDILLNFRTT FVSRKGEVVS NSKQIAINYL RGWFALDLLA ALPFDHLYAS 360
  361 DLYDGEDSHI HLVKLTRLLR LARLLQKIDR YSQHTAMILT LLMFSFTLAA HWLACIWYVI 420
  421 AVKEYEWFPE SNIGWLQLLA ERKNASVAIL TTAETYSTAL YFTFTSLTSV GFGNVSANTT 480
  481 AEKVFTIIMM LIGALMHAVV FGNVTAIIQR MYSRRSLYES KWRDLKDFVA LHNMPKELKQ 540
  541 RIEDYFQTSW SLSHGIDIYE TLREFPEELR GDVSMHLHRE ILQLPIFEAA SQGCLKLLSL 600
  601 HIKTNFCAPG EYLIHKGDAL NYIYYLCNGS MEVIKDDMVV AILGKGDLVG SDINVHLVAT 660
  661 SNGQMTATTN SAGQDVVVRS SSDIKALTYC DLKCIHMGGL VEVLRLYPEY QQQFANDIQH 720
  721 DLTCNLREGY ENQDSDIGPS FPLPSISEDD ENREEAEEGG KGEKENGGGP PSGASPLHNI 780
  781 SNSPLHATRS PLLGMGSPRN QRLHQRGRSL ITLRETNKRH RTLNAACSLD RGSFEEPEPL 840
  841 EEEQSSGGKR PSLERLDSQV STLHQDVAQL SAEVRNAISA LQEMTFTSNA MTSHSSLKFP 900
  901 PARSIPNISG VAGTRSGVAV EHGLMGGVLA AAELAAMQRS SSHPPEVWGR DVQLPTSNTA 960
  961 SSKAPSPVEP KKTMTSRSSQ TDFYRIDFPT FERFVLANPR LVLGLLGIEP AIKNEMDLLQ1020
 1021 QKQTLQISPL NTIDECVSPS DHNLASSKER LITSSAVPTP GRIYPPLDDE NSNDFRWTMK1080
 1081 HSASHHSCCK STDALLSPEE QPPISILPVD ATPAPSVQEV RSSKRSLRKS TSGSNSSLSS1140
 1141 SSSSSNSCLV SQSTGNLTTT NASVHCSNSS QSVASVATTR RASWKLQHSR SGEYRRLSEA1200
 1201 TAEYSPPAKT PLPVAGVSYG GDEEESVELL GPRRNSRPIL LGVSQNQGQG QAMNFRFSAG1260
 1261 DADKLEKGLR GLPSTRSLRD PSSK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..72]	PSI-BLAST	26.69897	Erg potassium channel, N-terminal domain
2	View Details	[73..588]	PSI-BLAST	3.154902	Botulinum neurotoxin
3	View Details	[589..739]	PSI-BLAST	42.0	HCN2J 443-645 in the presence of cGMP
4	View Details	[740..981]	deduced	N/A	No confident structure predictions are available.
5	View Details	[982..1188]	MSA	3.375995	View MSA. No confident structure predictions are available.
6	View Details	[1189..1284]	MSA	4.339995	View MSA. No confident structure predictions are available.

Protein Overview: elk-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: