| Protein: | elk-PA |
| Organism: | Drosophila melanogaster |
| Length: | 1284 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for elk-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
691.0 | [0..1] | [1284..1] |
|
Region A: Residues: [1-72] |
1 11 21 31 41 51
| | | | | |
1 MPARKGLLAP QNTFLDTIAT RFDGTHSNFV LGNAQANGNP IVYCSDGFVD LTGYSRAQIM 60
61 QKGCSCHFLY GP
|
| Detection Method: |  |
| Confidence: | 26.69897 |
| Match: | 1bywA |
| Description: | Erg potassium channel, N-terminal domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [73-588] |
1 11 21 31 41 51
| | | | | |
1 DTKEEHKQQI EKSLSNKMEL KLEVIFYKKE GAPFWCLFDI VPIKNEKRDV VLFLASHKDI 60
61 THTKMLEMNV NEECDSVFAL TAALLGARFR AGSNAGMLGL GGLPGLGGPA ASDGDTEAGE 120
121 GNNLDVPAGC NMGRRRSRAV LYQLSGHYKP EKGGVKTKLK LGNNFMHSTE APFPEYKTQS 180
181 IKKSRLILPH YGVFKGIWDW VILVATFYVA LMVPYNAAFA KADRQTKVSD VIVEALFIVD 240
241 ILLNFRTTFV SRKGEVVSNS KQIAINYLRG WFALDLLAAL PFDHLYASDL YDGEDSHIHL 300
301 VKLTRLLRLA RLLQKIDRYS QHTAMILTLL MFSFTLAAHW LACIWYVIAV KEYEWFPESN 360
361 IGWLQLLAER KNASVAILTT AETYSTALYF TFTSLTSVGF GNVSANTTAE KVFTIIMMLI 420
421 GALMHAVVFG NVTAIIQRMY SRRSLYESKW RDLKDFVALH NMPKELKQRI EDYFQTSWSL 480
481 SHGIDIYETL REFPEELRGD VSMHLHREIL QLPIFE
|
| Detection Method: | |
| Confidence: | 3.154902 |
| Match: | 1epwA |
| Description: | Botulinum neurotoxin |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| substrate-specific transmembrane transporter activity | 2.4673993239115 | bayes_pls_golite062009 |
| amine binding | 1.56690065078434 | bayes_pls_golite062009 |
| binding | 1.31086473286665 | bayes_pls_golite062009 |
| transporter activity | 1.29150662073327 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.07075219961504 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.801327928563072 | bayes_pls_golite062009 |
| carbohydrate binding | 0.703854404841118 | bayes_pls_golite062009 |
| protein binding | 0.505130802921086 | bayes_pls_golite062009 |
| sugar binding | 0.466177845826757 | bayes_pls_golite062009 |
| 0.394278984078131 | bayes_pls_golite062009 | |
| channel regulator activity | 0.37785202181286 | bayes_pls_golite062009 |
| receptor activity | 0.256839032951381 | bayes_pls_golite062009 |
| signal transducer activity | 0.149715597443623 | bayes_pls_golite062009 |
| molecular transducer activity | 0.149715597443623 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.0106003018506309 | bayes_pls_golite062009 |
|
Region A: Residues: [589-739] |
1 11 21 31 41 51
| | | | | |
1 AASQGCLKLL SLHIKTNFCA PGEYLIHKGD ALNYIYYLCN GSMEVIKDDM VVAILGKGDL 60
61 VGSDINVHLV ATSNGQMTAT TNSAGQDVVV RSSSDIKALT YCDLKCIHMG GLVEVLRLYP 120
121 EYQQQFANDI QHDLTCNLRE GYENQDSDIG P
|
| Detection Method: | |
| Confidence: | 42.0 |
| Match: | 1q3eA |
| Description: | HCN2J 443-645 in the presence of cGMP |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| cyclic nucleotide-gated ion channel activity | 11.4016635726548 | bayes_pls_golite062009 |
| intracellular cyclic nucleotide activated cation channel activity | 11.4016635726548 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 10.0964834385956 | bayes_pls_golite062009 |
| cation channel activity | 9.88287212109635 | bayes_pls_golite062009 |
| ion channel activity | 9.4846197809463 | bayes_pls_golite062009 |
| channel activity | 9.25176207085973 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 9.25176207085973 | bayes_pls_golite062009 |
| substrate-specific channel activity | 9.2472549851376 | bayes_pls_golite062009 |
| intracellular cGMP activated cation channel activity | 9.19973076787954 | bayes_pls_golite062009 |
| gated channel activity | 9.19042473454294 | bayes_pls_golite062009 |
| voltage-gated ion channel activity | 8.67936023319976 | bayes_pls_golite062009 |
| voltage-gated channel activity | 8.65591260847522 | bayes_pls_golite062009 |
| potassium channel activity | 8.63993986153386 | bayes_pls_golite062009 |
| cGMP binding | 7.7575871125398 | bayes_pls_golite062009 |
| voltage-gated potassium channel activity | 7.73925918789438 | bayes_pls_golite062009 |
| intracellular ligand-gated ion channel activity | 7.67206802696522 | bayes_pls_golite062009 |
| ligand-gated channel activity | 7.63607783812958 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 7.63607783812958 | bayes_pls_golite062009 |
| cyclic nucleotide binding | 7.37322432929433 | bayes_pls_golite062009 |
| voltage-gated cation channel activity | 6.98507387897677 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 5.54400173845933 | bayes_pls_golite062009 |
| GMP binding | 5.49455172024846 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 5.34760703274696 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 5.1138025954757 | bayes_pls_golite062009 |
| transporter activity | 3.30740141256752 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 3.24402760485462 | bayes_pls_golite062009 |
| transmembrane transporter activity | 3.22443361822344 | bayes_pls_golite062009 |
| intracellular cAMP activated cation channel activity | 3.18381716104784 | bayes_pls_golite062009 |
| binding | 1.14074551098763 | bayes_pls_golite062009 |
| protein binding | 0.560659365968498 | bayes_pls_golite062009 |
| signal transducer activity | 0.202809682876964 | bayes_pls_golite062009 |
| molecular transducer activity | 0.202809682876964 | bayes_pls_golite062009 |
|
Region A: Residues: [740-981] |
1 11 21 31 41 51
| | | | | |
1 SFPLPSISED DENREEAEEG GKGEKENGGG PPSGASPLHN ISNSPLHATR SPLLGMGSPR 60
61 NQRLHQRGRS LITLRETNKR HRTLNAACSL DRGSFEEPEP LEEEQSSGGK RPSLERLDSQ 120
121 VSTLHQDVAQ LSAEVRNAIS ALQEMTFTSN AMTSHSSLKF PPARSIPNIS GVAGTRSGVA 180
181 VEHGLMGGVL AAAELAAMQR SSSHPPEVWG RDVQLPTSNT ASSKAPSPVE PKKTMTSRSS 240
241 QT
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [982-1188] |
1 11 21 31 41 51
| | | | | |
1 DFYRIDFPTF ERFVLANPRL VLGLLGIEPA IKNEMDLLQQ KQTLQISPLN TIDECVSPSD 60
61 HNLASSKERL ITSSAVPTPG RIYPPLDDEN SNDFRWTMKH SASHHSCCKS TDALLSPEEQ 120
121 PPISILPVDA TPAPSVQEVR SSKRSLRKST SGSNSSLSSS SSSSNSCLVS QSTGNLTTTN 180
181 ASVHCSNSSQ SVASVATTRR ASWKLQH
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1189-1284] |
1 11 21 31 41 51
| | | | | |
1 SRSGEYRRLS EATAEYSPPA KTPLPVAGVS YGGDEEESVE LLGPRRNSRP ILLGVSQNQG 60
61 QGQAMNFRFS AGDADKLEKG LRGLPSTRSL RDPSSK
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
