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Protein Overview: gi|21627646, gi|...

General Information:
Name(s) found: gi|28573945 [NCBI NR]
gi|21627646 [NCBI NR]
Description(s) found:
Found 7 descriptions.
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  • gi|28573945|ref|NP_788293.1| Protein kinase related to protein kinase N CG2049-PD, isoform D [Drosophila melanogaster] [NCBI NR]
  • gi|21627646|gb|AAM68825.1| CG2049-PD, isoform D [Drosophila melanogaster] [NCBI NR]
    • Organism: Drosophila melanogaster
    Length: 1386 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALTMNMVFL KDLRSRLKGY LHGEYIKHPV LYELSHKYGF TENLPESCMS IRLEEIKEAI  60
   61 RREIRKELKI KEGAEKLREV AKDRRSLSDV AVLVKKSKSK LAELKSELQE LESQILLTSA 120
  121 NTAVNSNGQE SITACIDPNG GFLVSGAVGG LGGGNTALEG GAPATANDKV LASLEKQLQI 180
  181 EMKVKTGAEN MIQSLGIGCD KKLLAEAHQM LADSKAKIEF LRLRIIKVKQ NREQADRLKA 240
  241 SRQMIDEHGQ TIGGNNSSQP QSLETTLEER IEELRHRLRI EAAVVDGAKN VIRTLQTANR 300
  301 APDKKALQEA HGRLSESSRK LDLLRYSLDL RRQELPADSP AAQQLKTELQ IVQLSTSPAP 360
  361 VTYTSLQSGQ AGILGGKPYQ SVSSLGRCAS VTGKLEVRLL GCQDLLEDVP GRSRRDKDNN 420
  421 SSPGDLRSFV KGVTSRSSSK SYSVKDETSI EIMAVIKLDN ITVGQTSWKQ CSQQAWDQRF 480
  481 SIDLDRSREL EIGVYWRDWR SLCAVKVLRL EEFIDDVRHG MALQLEPQGL LFAEVKFLNP 540
  541 MISQKPKLRR QRMIFNRQQA KNISRAKQMN INVATWGRLL KRNAPNHVHM GSAGSGSSLT 600
  601 GSSPMVVGGS RDSESPISRT PSSDALVEPE PYTPGEQAQN LEFDPDAGIN EHVETPGEYP 660
  661 DPAASGLSGM RPLSMHMQGI SVLPPESPPV ATGAAGRPNT LSLQMPGASK GQVIQGGRTA 720
  721 APTTAPPPPP VLKATSTTPI LDQELQDALH EFDFLSDLDS RPTTLRRLLK EQKMALDAGA 780
  781 LENLLLQQQQ TEQQALQQRQ RQEQLRLQQF QEAQRQAILD LCVKQREPAE QTSPTLANQT 840
  841 PTFPPLASNQ IMPSLNARPC QSQSPNHNEF QLQPQPPHPA QKPTNPEPPS AVEQQLHRPV 900
  901 LILPPVVLLG GREEDRSVPP SPLVEYPEDD DEYLYRGSNE NLGTRLHSSH SSSAGDRFCV 960
  961 EVIPQLGKLY VGSSQQQYAQ QSSPIIQEPA TPTIYGNSAA AGAPQFPQPA QRQEKQPPQQ1020
 1021 QPIYANQYEL NVAKAAAAAS VYSPSSSTTS NSNQQQQQQR RNVARGLQYR ESGGLETGRA1080
 1081 GKQPPNAGML SMDNFRLLSV LGRGHFGKVI LSQLRSNNQY YAIKALKKGD IIARDEVESL1140
 1141 LSEKRIFEVA NAMRHPFLVN LYSCFQTEQH VCFVMEYAAG GDLMMHIHTD VFLEPRAVFY1200
 1201 AACVVLGLQY LHENKIIYRD LKLDNLLLDT EGYVKIADFG LCKEGMGFGD RTGTFCGTPE1260
 1261 FLAPEVLTET SYTRAVDWWG LGVLIFEMLV GELLRKNPER RLGSSERDAE DVKKQAFFRS1320
 1321 IVWDDLLLRK VKPPFVPTIN HLEDVSNFDE EFTSEKAQLT PPKEPRHLTE EEQLLFQDFS1380
 1381 YTAEWC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..155] PSI-BLAST 18.39794 Effector domain of the protein kinase pkn/prk1
    2 View Details [156..248] PSI-BLAST 25.30103 HR1b domain from PRK1
    3 View Details [249..353] FFAS03 2.1 HR1b domain from PRK1
    4 View Details [354..554] FFAS03 2.52 Human protein kinase C, eta
    5 View Details [555..699] deduced N/A No confident structure predictions are available.
    6 View Details [700..835] deduced N/A No confident structure predictions are available.
    7 View Details [836..1088] deduced N/A No confident structure predictions are available.
    8 View Details [1089..1386] PSI-BLAST 72.69897 No description for 2jdoA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8
    Term Confidence Notes
  • phosphotransferase activity, alcohol group as acceptor
    		•  5.49988294224815 bayes_pls_golite062009
  • protein kinase activity
    		•  5.4586557943719 bayes_pls_golite062009
  • kinase activity
    		•  5.3287080791198 bayes_pls_golite062009
  • cyclic nucleotide-dependent protein kinase activity
    		•  4.97855712164511 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.96052051118534 bayes_pls_golite062009
  • cAMP-dependent protein kinase activity
    		•  4.66277812893755 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  4.46381887831481 bayes_pls_golite062009
  • transferase activity
    		•  3.97138602499442 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  2.8153155526437 bayes_pls_golite062009
  • binding
    		•  2.74863538127007 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  2.59526003830791 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  2.54265774272269 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.40586892801446 bayes_pls_golite062009
  • signal transducer activity
    		•  2.40586892801446 bayes_pls_golite062009
  • receptor activity
    		•  2.39311927684508 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
    		•  2.16831387024372 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  2.10379226653669 bayes_pls_golite062009
  • ATP binding
    		•  1.97600611746091 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.93596671856664 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.90928021591891 bayes_pls_golite062009
  • acetylcholine receptor activator activity
    		•  1.83545227594542 bayes_pls_golite062009
  • phosphoinositide 3-kinase binding
    		•  1.82515074380651 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
    		•  1.81249386965144 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.65732943334212 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.65726906484847 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.63763394711025 bayes_pls_golite062009
  • nucleotide binding
    		•  1.63195828048121 bayes_pls_golite062009
  • insulin receptor substrate binding
    		•  1.62657794525303 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.56748951434625 bayes_pls_golite062009
  • DNA binding
    		•  1.35333135345112 bayes_pls_golite062009
  • kinase binding
    		•  1.26086833316556 bayes_pls_golite062009
  • ErbB-3 class receptor binding
    		•  1.25765701903393 bayes_pls_golite062009
  • protein binding
    		•  1.22565748038754 bayes_pls_golite062009
  • catalytic activity
    		•  1.21655087018101 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.16049201286103 bayes_pls_golite062009
  • transporter activity
    		•  1.11833481501707 bayes_pls_golite062009
  • transcription factor activity
    		•  1.10928254946881 bayes_pls_golite062009
  • protein kinase binding
    		•  1.06030596516506 bayes_pls_golite062009
  • ErbB-2 class receptor binding
    		•  1.02996109010965 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.97575992765505 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  0.959360414036299 bayes_pls_golite062009
  • growth factor binding
    		•  0.86076618871384 bayes_pls_golite062009
  • MAP kinase activity
    		•  0.81943579965027 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.705905455086486 bayes_pls_golite062009
  • protein serine/threonine/tyrosine kinase activity
    		•  0.48345772948903 bayes_pls_golite062009
  • enzyme binding
    		•  0.46284745266176 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.450699332958421 bayes_pls_golite062009
  • protein kinase C activity
    		•  0.41587987561486 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.393328812780268 bayes_pls_golite062009
  • MAP kinase kinase kinase activity
    		•  0.37115026509016 bayes_pls_golite062009
  • MAP kinase kinase activity
    		•  0.35402045013148 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.284465446035567 bayes_pls_golite062009
  • insulin receptor binding
    		•  0.266450215230107 bayes_pls_golite062009
  • protein complex binding
    		•  0.239339759110451 bayes_pls_golite062009
  • insulin receptor activity
    		•  0.237134032032089 bayes_pls_golite062009
  • SH2 domain binding
    		•  0.226760162354251 bayes_pls_golite062009
  • transforming growth factor beta receptor activity
    		•  0.20643152368029 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase activity
    		•  0.20643152368029 bayes_pls_golite062009
  • receptor binding
    		•  0.197402253061255 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.148194101970458 bayes_pls_golite062009
  • actin binding
    		•  0.144822861207099 bayes_pls_golite062009
  • peptide binding
    		•  0.118578378753757 bayes_pls_golite062009
  • transforming growth factor beta receptor activity, type I
    		•  0.0506751594607393 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.0405961152540697 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.0040394359628233 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.85

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle