General Information: |
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Name(s) found: |
MLH1_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 757 amino acids |
Gene Ontology: |
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Cellular Component: |
condensed chromosome
[UNKNOWN]
chiasma [UNKNOWN] nucleus [IDA][IEA] MutLalpha complex [UNKNOWN] chromosome [UNKNOWN] synaptonemal complex [UNKNOWN][IDA] condensed nuclear chromosome [UNKNOWN] male germ cell nucleus [UNKNOWN] |
Biological Process: |
somatic recombination of immunoglobulin gene segments
[UNKNOWN]
DNA repair [UNKNOWN] reciprocal meiotic recombination [UNKNOWN] pachytene [UNKNOWN] resolution of meiotic recombination intermediates [UNKNOWN] double-strand break repair via nonhomologous end joining [UNKNOWN] response to toxin [IEP] response to hypoxia [IEP] meiotic chromosome segregation [UNKNOWN] isotype switching [UNKNOWN] male meiosis chromosome segregation [UNKNOWN] male meiosis [UNKNOWN] spermatogenesis [UNKNOWN][IEP] DNA damage response, signal transduction resulting in induction of apoptosis [UNKNOWN] mismatch repair [UNKNOWN][IEA] negative regulation of mitotic recombination [UNKNOWN] response to DNA damage stimulus [UNKNOWN] nuclear-transcribed mRNA poly(A) tail shortening [UNKNOWN] cell cycle [IEA] meiosis [UNKNOWN] meiotic metaphase I plate congression [UNKNOWN] spindle midzone assembly involved in meiosis [UNKNOWN] somatic recombination of immunoglobulin genes during immune response [UNKNOWN] oogenesis [UNKNOWN] response to drug [IEP] cellular response to organic cyclic substance [IEP] somatic hypermutation of immunoglobulin genes [UNKNOWN] |
Molecular Function: |
MutSalpha complex binding
[UNKNOWN]
ATP binding [IEA] protein binding [UNKNOWN] mismatched DNA binding [IEA] structure-specific DNA binding [UNKNOWN] molecular_function [ND] guanine/thymine mispair binding [UNKNOWN] single-stranded DNA binding [UNKNOWN] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MSFVAGVIRR LDETVVNRIA AGEVIQRPAN AIKEMTENCL DAKSTNIQVI VREGGLKLIQ 60 61 IQDNGTGIRK EDLDIVCERF TTSKLQTFED LAMISTYGFR GEALASISHV AHVTITTKTA 120 121 DGKCAYRASY SDGKLQAPPK PCAGNQGTLI TVEDLFYNII TRKKALKNPS EEYGKILEVV 180 181 GRYSIHNSGI SFSVKKQGET VSDVRTLPNA TTVDNIRSIF GNAVSRELIE VGCEDKTLAF 240 241 KMNGYISNAN YSVKKCIFLL FINHRLVESA ALKKAIEAVY AAYLPKNTHP FLYLILEISP 300 301 QNVDVNVHPT KHEVHFLHEE SILERVQQHI ESKLLGSNSS RMYFTQTLLP GLAGPSGEAV 360 361 KSTTGIASSS TSGSGDKVHA YQMVRTDSRD QKLDAFMQPV SRRLPSQPQD PVPGNRTEGS 420 421 PEKAMQKDQE ISELPAPMEA AADSASLERE SVIGASEVVA PQRHPSSPGS SRKRHPEDSD 480 481 VEMMENDSRK EMTAACYPRR RIINLTSVLS LQEEINDRGH ETLREMLRNH TFVGCVNPQW 540 541 ALAQHQTKLY LLNTTKLSEE LFYQILIYDF ANFGVLRLPE PAPLFDFAML ALDSPESGWT 600 601 EEDGPKEGLA EYIVEFLKKK AKMLADYFSV EIDEEGNLIG LPLLIDSYVP PLEGLPIFIL 660 661 RLATEVNWDE EECFESLSKE CAVFYSIRKQ YILEESALSG QQSDMPGSPS KPWKWTVEHI 720 721 IYKAFRSHLL PPKHFTEDGN VLQLANLPDL CKVFERC |
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.99 |
Source: Reynolds et al. (2008)