| General Information: |
|
| Name(s) found: |
INSR_RAT
[Swiss-Prot]
|
| Description(s) found:
SHOW ONLY BEST |
|
| Organism: | Rattus norvegicus |
| Length: | 1383 amino acids |
Gene Ontology: |
|
| Cellular Component: |
microsome
[UNKNOWN][IDA]
synapse [IDA] plasma membrane [UNKNOWN][IDA] insulin receptor complex [UNKNOWN][IEA] nucleus [IDA] integral to plasma membrane [UNKNOWN] caveola [UNKNOWN][IEA] soluble fraction [IDA] endosome [IDA] membrane [UNKNOWN][IEA] integral to membrane [IEA] cytosol [IDA] endosome membrane [UNKNOWN] |
| Biological Process: |
peptidyl-tyrosine phosphorylation
[UNKNOWN][IMP]
protein amino acid autophosphorylation [UNKNOWN][IDA][IEA][IMP] fat cell differentiation [IEP] positive regulation of mitosis [UNKNOWN][IEA] positive regulation of glycogen biosynthetic process [UNKNOWN][IEA] positive regulation of developmental growth [UNKNOWN][IEA] protein heterotetramerization [UNKNOWN][IDA] activation of MAPK activity [UNKNOWN][IEA] heart morphogenesis [UNKNOWN][IEA] response to glucose stimulus [IEP] transformation of host cell by virus [UNKNOWN][IEA] response to testosterone stimulus [IEP] G-protein coupled receptor protein signaling pathway [UNKNOWN][IEA] response to hormone stimulus [IEP] response to peptide hormone stimulus [IEA] organ morphogenesis [UNKNOWN] negative regulation of gene expression [IMP] glucose homeostasis [UNKNOWN][IDA] response to estradiol stimulus [IEP] response to activity [IEP] response to nutrient levels [IEP] positive regulation of protein kinase B signaling cascade [UNKNOWN][IEA] positive regulation of cell migration [UNKNOWN][IEA] response to tumor necrosis factor [IMP] response to manganese ion [IEP] positive regulation of nitric oxide biosynthetic process [UNKNOWN][IEA] positive regulation of glycoprotein biosynthetic process [IMP] response to vitamin D [IEP] positive regulation of respiratory burst [UNKNOWN][IEA] insulin receptor signaling pathway [UNKNOWN][IDA][IMP] positive regulation of cell proliferation [UNKNOWN][IEA] positive regulation of DNA replication [UNKNOWN][IEA] protein amino acid phosphorylation [IDA] positive regulation of glycolysis [UNKNOWN][IEA] cellular response to insulin stimulus [UNKNOWN] response to ethanol [IEP] response to insulin stimulus [IEP] response to glucocorticoid stimulus [IEP] activation of protein kinase activity [UNKNOWN] regulation of hydrogen peroxide metabolic process [IDA] exocrine pancreas development [UNKNOWN][IEA] response to protein stimulus [IEP] activation of protein kinase B activity [UNKNOWN][IEA] positive regulation of phosphorylation [IDA] regulation of gene-specific transcription [UNKNOWN][IEA] regulation of embryonic development [UNKNOWN][IEA] transmembrane receptor protein tyrosine kinase signaling pathway [IEA] positive regulation of glucose import [UNKNOWN] positive regulation of MAPKKK cascade [UNKNOWN][IEA] male sex determination [UNKNOWN][IEA] negative regulation of protein amino acid phosphorylation [IMP] positive regulation of protein amino acid phosphorylation [UNKNOWN][IEA] negative regulation of transporter activity [IMP] |
| Molecular Function: |
phosphoinositide 3-kinase binding
[UNKNOWN][IEA]
3-phosphoinositide-dependent protein kinase binding [IDA] insulin-like growth factor receptor binding [UNKNOWN][IEA] nucleotide binding [IEA] GTP binding [UNKNOWN][IEA] ATP binding [UNKNOWN][IEA] protein tyrosine kinase activity [UNKNOWN][IDA] insulin receptor activity [UNKNOWN][IDA][IMP] transmembrane receptor protein tyrosine kinase activity [IEA] receptor signaling protein tyrosine kinase activity [UNKNOWN][IEA] protein complex binding [IDA] insulin-like growth factor I binding [UNKNOWN][IEA] insulin-like growth factor II binding [UNKNOWN][IEA] PTB domain binding [UNKNOWN][IEA] protein kinase binding [IPI] insulin binding [UNKNOWN][IDA][IMP] protein domain specific binding [IPI] protein phosphatase binding [IMP] protein kinase activity [IDA] receptor activity [IEA] SH2 domain binding [UNKNOWN][IEA] protein binding [UNKNOWN][IEA][IPI] lipoic acid binding [IPI] metal ion binding [IEA] insulin receptor substrate binding [UNKNOWN][IMP] transferase activity [IEA] |
| Sequence: |
|
| Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51
| | | | | |
1 MGSGRGCETT AVPLLMAVAV AGGTAGHLYP GEVCPGMDIR NNLTRLHELE NCSVIEGHLQ 60
61 ILLMFKTRPE DFRDLSFPKL IMITDYLLLF RVYGLESLKD LFPNLTVIRG SRLFFNYALV 120
121 IFEMVHLKEL GLYNLMNITR GSVRIEKNNE LCYLATIDWS RILDYVEDNY IVLNKDDNEE 180
181 CGDVCPGTAK GKTNCPATVI NGQFVERCWT HSHCQKVCPT ICKSHGCTAE GLCCHKECLG 240
241 NCSEPDDPTK CVACRNFYLD GQCVETCPPP YYHFQDWRCV NFSFCQDLHY KCRNSRKPGC 300
301 HQYVIHNNKC IPECPSGYTM NSSNLMCTPC LGPCPKVCQI LEGEKTIDSV TSAQELRGCT 360
361 VINGSLIINI RGGNNLAAEL EANLGLIEEI SGFLKIRRSY ALVSLSFFRK LHLIRGETLE 420
421 IGNYSFYALD NQNLRQLWDW NKHNLTITQG KLFFHYNPKL CLSEIHKMEE VSGTKGRQER 480
481 NDIALKTNGD QASCENELLK FSFIRTSFDK ILLRWEPYWP PDFRDLLGFM LFYKEAPYQN 540
541 VTEFDGQDAC GSNSWTVVDI DPPQRSNDPK SQTPSHPGWL MRGLKPWTQY AIFVKTLVTF 600
601 SDERRTYGAK SDIIYVQTDA TNPSVPLDPI SVSNSSSQII LKWKPPSDPN GNITHYLVYW 660
661 ERQAEDSELF ELDYCLKGLK LPSRTWSPPF ESDDSQKHNQ SEYDDSASEC CSCPKTDSQI 720
721 LKELEESSFR KTFEDYLHNV VFVPRKTSSG NGAEDTRPSR KRRSLEEVGN VTATTPTLPD 780
781 FPNISSTIAP TSHEEHRPFE KVVNKESLVI SGLRHFTGYR IELQACNQDS PEERSGVAAY 840
841 VSARTMPEAK ADDIVGPVTH EIFENNVVHL MWQEPKEPNG LIVLYEVSYR RYGDEELHLC 900
901 VSRKHFALER GCRLRGLSPG NYSVRVRATS LAGNGSWTEP TYFYVTDYLD VPSNIAKIII 960
961 GPLIFVFLFS VVIGSIYLFL RKRQPDGPMG PLYASSNPEY LSASDVFPSS VYVPDEWEVP1020
1021 REKITLLREL GQGSFGMVYE GNAKDIIKGE VETRVAVKTV NESASLRERI EFLNEASVMK1080
1081 GFTCHHVVRL LGVVSKGQPT LVVMELMAHG DLKSHLRSLR PDAENNPGRP PPTLQEMIQM1140
1141 TAEIADGMAY LNAKKFVHRD LAARNCMVAH DFTVKIGDFG MTRDIYETDY YRKGGKGLLP1200
1201 VRWMSPESLK DGVFTASSDM WSFGVVLWEI TSLAEQPYQG LSNEQVLKFV MDGGYLDPPD1260
1261 NCPERLTDLM RMCWQFNPKM RPTFLEIVNL LKDDLHPSFP EVSFFYSEEN KAPESEELEM1320
1321 EFEDMENVPL DRSSHCQREE AGCREGGSSL SIKRTYDEHI PYTHMNGGKK NGRVLTLPRS1380
1381 NPS |
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