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Any process that modulates the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound. Any process that increases the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound. Any process that activates or increases the frequency, rate or extent of a signaling pathway. A cascade of at least three protein kinase activities culminating in the phosphorylation and activation of a MAP kinase. MAPKKK cascades lie downstream of numerous signaling pathways. Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the BMK cascade. Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade. Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade. Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade. Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade. Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade. The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands resulting in an increase in the rate or frequency of a MAPKKK cascade. A series of reactions that occur within the cell, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: positive regulation of MAPKKK cascade
Acc: GO:0043410
Aspect: Biological Process
Desc: Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
Synonyms:
  • positive regulation of mitogen-activated protein kinase kinase kinase cascade
  • upregulation of MAPKKK cascade
  • stimulation of MAPKKK cascade
  • activation of MAPKKK cascade
  • positive regulation of MAP kinase kinase kinase cascade
  • up-regulation of MAPKKK cascade
  • positive regulation of mitogen activated protein kinase kinase kinase cascade
  • up regulation of MAPKKK cascade
Proteins in PDR annotated with:
   This term: 110 [Search]
   Term or descendants: 241 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043410 - positive regulation of MAPKKK cascade (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle