Protein Overview: gi|109510034

General Information:
Name(s) found:	gi\|109510034 [NCBI NR]
Description(s) found: Found 2 descriptions. SHOW ALL	gi\|109510034\|ref\|XP_001080493.1\| PREDICTED: similar to NAD-dependent deacetylase sirtuin-1 (SIR2alpha) (mSIR2a) (Sir2) (SIR2-like protein 1) [Rattus norvegicus] [NCBI NR]
Organism:	Rattus norvegicus
Length:	799 amino acids
Gene Ontology:
Cellular Component:	nuclear envelope [UNKNOWN] nucleus [UNKNOWN][IDA] PML body [UNKNOWN] [NOT]cytoplasm [UNKNOWN] rDNA heterochromatin [UNKNOWN] nucleolus [UNKNOWN] cellular_component [ND] chromatin silencing complex [UNKNOWN] nucleoplasm [UNKNOWN]
Biological Process:	biological_process [ND] negative regulation of DNA damage response, signal transduction by p53 class mediator [UNKNOWN] spermatogenesis [UNKNOWN] establishment of chromatin silencing [UNKNOWN] maintenance of chromatin silencing [UNKNOWN] protein amino acid deacetylation [UNKNOWN][IDA][IEA] negative regulation of transcription factor activity [UNKNOWN] chromatin silencing [IEA] response to DNA damage stimulus [UNKNOWN] regulation of transcription [IEA] regulation of cell proliferation [UNKNOWN] ovulation from ovarian follicle [UNKNOWN] chromatin silencing at rDNA [UNKNOWN] negative regulation of transcription [UNKNOWN] negative regulation of helicase activity [UNKNOWN] positive regulation of chromatin silencing [UNKNOWN] regulation of protein import into nucleus, translocation [UNKNOWN] peptidyl-lysine deacetylation [UNKNOWN] histone deacetylation [UNKNOWN] response to nutrient levels [IEP] histone H3 deacetylation [IDA]
Molecular Function:	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [IEA] zinc ion binding [IEA] identical protein binding [UNKNOWN] protein C-terminus binding [UNKNOWN] molecular_function [ND] p53 binding [UNKNOWN] protein binding [UNKNOWN] NAD-dependent protein deacetylase activity [UNKNOWN] histone binding [UNKNOWN] deacetylase activity [UNKNOWN] transcription repressor activity [UNKNOWN] NAD-dependent histone deacetylase activity [UNKNOWN][IDA] NAD binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEVSPLRRQ GHSELAGNRK AFFISAGLSK PVNTQTSTQP FANTSSHWLF AQHRACRAGL  60
   61 LGSEGRRRPA WAPFCLSGLG KARGKSRLEA KAGRQGARVR PRWELAAPFA NLGHRGDPPR 120
  121 AGGAERPPRR ARPPWAARGP DSCEGSAAAA QLGPGSAARR RARQPYCGAA RGLAARLGRL 180
  181 ALLRAVAGAA GSRSCHNLLL ADEIITNGFH SCESDDDDRA SHASSSDWTP RPRIGPYTFV 240
  241 QQHLMIGTDP RTILKDLLPE TIPPPELDDM TLWQIVINIL SEPPKRKKRK DINTIEDAVK 300
  301 LLQECKKIIV LTGAGVSVSC GIPDFRSRDG IYARLAVDFP DLPDPQAMFD IEYFRKDPRP 360
  361 FFKFAKEIYP GQFQPSLCHK FIALSDKEGK LLRNYTQNID TLEQVAGIQR IIQCHGSFAT 420
  421 ASCLICKYKV DCEAVRGDIF NQVVPRCPRC PADEPLAIMK PEIVFFGENL PEQFHRAMKY 480
  481 DKDEVDLLIV IGSSLKVRPV ALIPSSIPHE VPQILINREP LPHLHFDVEL LGDCDVIINE 540
  541 LCHRLGGEYA KLCCNPVKLS EITEKPPRTQ KELVHLSELP PTPLHISEDS SSPERTVPQD 600
  601 SSVIATLVDQ TIKNKVDDLE VSEPKSCVEE KSQEVQTYRN VESINVENPD FKAVGSSTGD 660
  661 KNERTSVAET VRKCWPNRLA KEQISKRLDG NQYLFVPPNR YIFHGAEVYS DSEDDALSSS 720
  721 SCGSNSDSGT CQSPSLEEPL EDESEIEEFY NGLEDDADRP ECAGGSGADG GDQEAVNEAI 780
  781 AMKQELTDVN CTPDKSEHY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.91

Protein Overview: gi|109510034

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: